NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2098123071|ref|XP_043661559|]
View 

repressor of RNA polymerase III transcription MAF1 homolog isoform X1 [Drosophila teissieri]

Protein Classification

repressor of RNA polymerase III transcription MAF1( domain architecture ID 10557763)

repressor of RNA polymerase III transcription MAF1 plays a role in the repression of RNA polymerase III-mediated transcription in response to changing nutritional, environmental and cellular stress conditions

CATH:  3.40.1000.50
Gene Ontology:  GO:0016480|GO:0000994|GO:0000992

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Maf1 pfam09174
Maf1 regulator; Maf1 is a negative regulator of RNA polymerase III. It targets the initiation ...
25-204 3.78e-86

Maf1 regulator; Maf1 is a negative regulator of RNA polymerase III. It targets the initiation factor TFIIIB.


:

Pssm-ID: 462704  Cd Length: 174  Bit Score: 252.55  E-value: 3.78e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  25 IFGRIESYSCKMVAAEKVLYKRFTAD-------SHGHDLQALS-PPQTLTDFSPNFrrnnsqsgdegiTLCDTISRKTLF 96
Cdd:pfam09174   1 ITGRLELYSCKAAGSDKKLYKSIEKElesqyesLLPLSASLSSaPSLNLSSSSPFG------------PLSDTSSRKTLA 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  97 YLIATLNASFePDYDFSEAKSHEFSKEPSLQWVMNSIHANLSALAGDqYQVIRQPLWSAVDDEVILSECDIYSYNPDLSC 176
Cdd:pfam09174  69 YLIATLNASF-PDYDFSHLRPDDFSKEPSLRSVMNNIDSTLSNILGD-YSSLRPKLWAAIDEEISLKDCDIYSYNPDDDS 146
                         170       180
                  ....*....|....*....|....*...
gi 2098123071 177 DPFGEPGCLWSFNYFFYNKKLKRIVFFT 204
Cdd:pfam09174 147 DPFGEEGALWSFNYFFYNKKLKRVLFFY 174
 
Name Accession Description Interval E-value
Maf1 pfam09174
Maf1 regulator; Maf1 is a negative regulator of RNA polymerase III. It targets the initiation ...
25-204 3.78e-86

Maf1 regulator; Maf1 is a negative regulator of RNA polymerase III. It targets the initiation factor TFIIIB.


Pssm-ID: 462704  Cd Length: 174  Bit Score: 252.55  E-value: 3.78e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  25 IFGRIESYSCKMVAAEKVLYKRFTAD-------SHGHDLQALS-PPQTLTDFSPNFrrnnsqsgdegiTLCDTISRKTLF 96
Cdd:pfam09174   1 ITGRLELYSCKAAGSDKKLYKSIEKElesqyesLLPLSASLSSaPSLNLSSSSPFG------------PLSDTSSRKTLA 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  97 YLIATLNASFePDYDFSEAKSHEFSKEPSLQWVMNSIHANLSALAGDqYQVIRQPLWSAVDDEVILSECDIYSYNPDLSC 176
Cdd:pfam09174  69 YLIATLNASF-PDYDFSHLRPDDFSKEPSLRSVMNNIDSTLSNILGD-YSSLRPKLWAAIDEEISLKDCDIYSYNPDDDS 146
                         170       180
                  ....*....|....*....|....*...
gi 2098123071 177 DPFGEPGCLWSFNYFFYNKKLKRIVFFT 204
Cdd:pfam09174 147 DPFGEEGALWSFNYFFYNKKLKRVLFFY 174
MAF1 COG5046
Protein involved in Mod5 protein sorting [Posttranslational modification, protein turnover, ...
91-202 2.22e-18

Protein involved in Mod5 protein sorting [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227379  Cd Length: 282  Bit Score: 81.59  E-value: 2.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  91 SRKTLFYLIATLNASFePDYDFSEAKSHEFSKEPSLQWVMNSIHANLsalagdqYQVIRQPL-----WSAVDDEVILSEC 165
Cdd:COG5046   130 SRSKFNYLFAKLNASY-PDHDFSSEAPTDFSKRRSLGRFVEKPLGTL-------LSAGRLRFpydfcWESIGSHRRLSDC 201
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2098123071 166 DIYSYNPDLSCDPFGEPGCLWSFNYFFYNKKLKRIVF 202
Cdd:COG5046   202 EVLNYMPYSISTTHKNSDDVWEFVGFLENILHKRVSY 238
 
Name Accession Description Interval E-value
Maf1 pfam09174
Maf1 regulator; Maf1 is a negative regulator of RNA polymerase III. It targets the initiation ...
25-204 3.78e-86

Maf1 regulator; Maf1 is a negative regulator of RNA polymerase III. It targets the initiation factor TFIIIB.


Pssm-ID: 462704  Cd Length: 174  Bit Score: 252.55  E-value: 3.78e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  25 IFGRIESYSCKMVAAEKVLYKRFTAD-------SHGHDLQALS-PPQTLTDFSPNFrrnnsqsgdegiTLCDTISRKTLF 96
Cdd:pfam09174   1 ITGRLELYSCKAAGSDKKLYKSIEKElesqyesLLPLSASLSSaPSLNLSSSSPFG------------PLSDTSSRKTLA 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  97 YLIATLNASFePDYDFSEAKSHEFSKEPSLQWVMNSIHANLSALAGDqYQVIRQPLWSAVDDEVILSECDIYSYNPDLSC 176
Cdd:pfam09174  69 YLIATLNASF-PDYDFSHLRPDDFSKEPSLRSVMNNIDSTLSNILGD-YSSLRPKLWAAIDEEISLKDCDIYSYNPDDDS 146
                         170       180
                  ....*....|....*....|....*...
gi 2098123071 177 DPFGEPGCLWSFNYFFYNKKLKRIVFFT 204
Cdd:pfam09174 147 DPFGEEGALWSFNYFFYNKKLKRVLFFY 174
MAF1 COG5046
Protein involved in Mod5 protein sorting [Posttranslational modification, protein turnover, ...
91-202 2.22e-18

Protein involved in Mod5 protein sorting [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227379  Cd Length: 282  Bit Score: 81.59  E-value: 2.22e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2098123071  91 SRKTLFYLIATLNASFePDYDFSEAKSHEFSKEPSLQWVMNSIHANLsalagdqYQVIRQPL-----WSAVDDEVILSEC 165
Cdd:COG5046   130 SRSKFNYLFAKLNASY-PDHDFSSEAPTDFSKRRSLGRFVEKPLGTL-------LSAGRLRFpydfcWESIGSHRRLSDC 201
                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2098123071 166 DIYSYNPDLSCDPFGEPGCLWSFNYFFYNKKLKRIVF 202
Cdd:COG5046   202 EVLNYMPYSISTTHKNSDDVWEFVGFLENILHKRVSY 238
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH