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Conserved domains on  [gi|299825766|ref|YP_003734694|]
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ATP synthase F0 subunit 6 (mitochondrion) [Coilia lindmani]

Protein Classification

ATP synthase F0 subunit 6( domain architecture ID 10009577)

ATP synthase F0 subunit 6 is part of the mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V), which produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-227 3.27e-148

ATP synthase F0 subunit 6; Provisional


:

Pssm-ID: 177190  Cd Length: 227  Bit Score: 411.57  E-value: 3.27e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-227 3.27e-148

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 411.57  E-value: 3.27e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-227 5.62e-52

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 167.38  E-value: 5.62e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766    4 SFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSR-WINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFLIT 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRwLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   83 LNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 299825766  163 ANLTAGHLLIQLIATAAFVLlpLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLLFSL--MSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYLNDAL 226
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-224 3.80e-41

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 137.53  E-value: 3.80e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  66 GHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 299825766 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILtatVLFLLTLLEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLL---LPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP-synt_A pfam00119
ATP synthase A chain;
19-224 2.25e-36

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 127.22  E-value: 2.25e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   19 LIAVAIILPWILYPTP-TSRWINNRLLTLQGWFINRLSQQIFLPI-NQGGHKWAVLLTSLMIFLITLNMLGLL---PYTF 93
Cdd:pfam00119   5 LIVALILLLFLLLATRkTKKLVPGRLQNFVEMLVEFVDNIVKDNIgKKKGRKFFPLLLTLFFFILVSNLLGLIpksPGGF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   94 TPTTQLSLNMAFAVPLWLATVIIGMRNQPTAA-LGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLI 172
Cdd:pfam00119  85 TVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 299825766  173 QLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:pfam00119 165 LLLAGLIFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 49-225 9.39e-26

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 99.38  E-value: 9.39e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  49 WFINRLSQQIFLPINQGGHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAA-LG 127
Cdd:COG0356   37 MLVEFVRNQVKDTIGKKGRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLK 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 128 HLLPEGTPtPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLplmptVAILTATVLFLLTLLEVAV 207
Cdd:COG0356  117 HLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAGHIILLLLAGLAPFLL-----LGVLSLLLPVAWTAFELLV 190

                        170
                 ....*....|....*...
gi 299825766 208 AMIQAYVFVLLLSLYLQE 225
Cdd:COG0356  191 GFLQAYIFTMLTAVYISL 208
 
Name Accession Description Interval E-value
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 1-227 3.27e-148

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 411.57  E-value: 3.27e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00132   1 MTLSFFDQFMSPTYLGIPLIALALTLPWILFPTPTSRWLNNRLLTLQGWFINRFTQQLLLPLNVGGHKWALLLTSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00132  81 ITLNMLGLLPYTFTPTTQLSLNMGLAVPLWLATVIIGMRNQPTHALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00132 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATLLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
ATP6 MTH00073
ATP synthase F0 subunit 6; Provisional
 1-227 9.83e-124

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177144  Cd Length: 227  Bit Score: 349.65  E-value: 9.83e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00073   1 MNLSFFDQFLSPTLLGIPLIMLAMLLPWLLFPTPTNKWLNNRLSTLQIWFLQNFTKQLMLPLNTPGHKWALILTSLMVFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00073  81 ITMNLLGLLPYTFTPTTQLSLNLGLAVPLWLATVLIGLRNQPTASLGHLLPEGTPTLLIPILIIIETISLFIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00073 161 LTANLTAGHLLIQLISTATLVLLPLMPTVSILTMIVLFLLTLLEIAVAMIQAYVFVLLLSLYLQENV 227
ATP6 MTH00120
ATP synthase F0 subunit 6; Provisional
 1-227 4.55e-112

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177181  Cd Length: 227  Bit Score: 320.23  E-value: 4.55e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00120   1 MNLNFFDQFSSPELLGIPLILLAMLIPALLIPSPKNRLLTNRLTTLQLWLIKLITKQLMLPLNKKGHKWALILTSLMLLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00120  81 LLINLLGLLPYTFTPTTQLSMNMALAIPLWLATVLTGLRNQPTTSLAHLLPEGTPTPLIPALILIETISLLIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00120 161 LTANLTAGHLLIQLISTATLNLLPTMPTLSLLTLIILLLLTILELAVAMIQAYVFVLLLSLYLQENT 227
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 1-227 4.61e-100

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 289.93  E-value: 4.61e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00179   1 MMLSMFDQFESPSLLGIPLLALALLLPWLLFPSLTNRWLNNRLSTLQSWFFGSFTFQLMQPINKKGHKWAVLFLSLMLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00179  81 LTLNLLGLLPYTFTPTTQLSLNLGLALPLWLGTVLYGLFNQPTIALAHLLPEGTPTPLIPMLVWIETISLLIRPLALGVR 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00179 161 LTANITAGHLLMHLISSAVFVLMNFMGMVALLTLLVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENL 227
ATP6 MTH00101
ATP synthase F0 subunit 6; Validated
 1-226 2.60e-83

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177163  Cd Length: 226  Bit Score: 247.17  E-value: 2.60e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTPTsRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFL 80
Cdd:MTH00101   1 MNENLFASFITPTILGLPIVTLIIMFPSLLFPTPN-RLINNRLISIQQWLIQLTSKQMMTIHNTKGQTWSLMLMSLILFI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  81 ITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVR 160
Cdd:MTH00101  80 GSTNLLGLLPHSFTPTTQLSMNLGMAIPLWAGTVITGFRNKTKASLAHFLPQGTPTPLIPMLVIIETISLFIQPMALAVR 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 299825766 161 LTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
Cdd:MTH00101 160 LTANITAGHLLIHLIGGATLALMSISTTTALITFIILILLTILEFAVALIQAYVFTLLVSLYLHDN 225
ATP6 MTH00035
ATP synthase F0 subunit 6; Validated
 4-227 2.07e-54

ATP synthase F0 subunit 6; Validated


Pssm-ID: 177110  Cd Length: 229  Bit Score: 174.01  E-value: 2.07e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   4 SFFDQFMSPTYMGIPL--IAVAIILPWILYPTPTSrWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFLI 81
Cdd:MTH00035   6 SIFGQFSPDTILFIPLtlLSSVIALSWLFFINPTN-WLPSRSQSIWLTFRQEILKLIFQNTNPNTAPWAGLLTTVFILIL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  82 TLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVRL 161
Cdd:MTH00035  85 SINVLGLFPYAFTSTSHISLTYSLGIPLWMSVNILGFYLAFNSRLSHLVPQGTPSFLIPLMVWIETLSLFAQPIALGLRL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 299825766 162 TANLTAGHLLIQLIATAAFVLLPLmPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:MTH00035 165 AANLTAGHLLIFLLSTAIWELSNS-PLISIITLIIFFLLFILEIGVACIQAYVFTALVHFYLEQNI 229
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 4-227 5.62e-52

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 167.38  E-value: 5.62e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766    4 SFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSR-WINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFLIT 82
Cdd:TIGR01131   4 QFDISPITLFSLTLLSLILLLSLLIFLISSSLSRwLIPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   83 LNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVRLT 162
Cdd:TIGR01131  84 SNLLGLIPYSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLAHLVPSGTPLPLIPFLVIIETISYLARPISLSVRLF 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 299825766  163 ANLTAGHLLIQLIATAAFVLlpLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQENV 227
Cdd:TIGR01131 164 ANISAGHLLLTLLSGLLFSL--MSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYLNDAL 226
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 1-225 1.29e-45

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 151.09  E-value: 1.29e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWILYPTptSRW-INNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIF 79
Cdd:MTH00157   1 MMTNLFSIFDPSTSFNLSLNWLSTFLGLLFIPS--SFWlIPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  80 LITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGV 159
Cdd:MTH00157  79 ILFNNFLGLFPYIFTSTSHLSLTLSLALPLWLSFMLFGWINNTNHMFAHLVPQGTPPILMPFMVLIETISNLIRPGTLAV 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 299825766 160 RLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTatvLFLLTLLEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:MTH00157 159 RLAANMIAGHLLLTLLGNTGPSLSSMILSILILI---QILLLILESAVAIIQSYVFSVLSTLYSSE 221
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 1-226 9.38e-44

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 146.72  E-value: 9.38e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPWI-LYPTPTSRWI-NNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMI 78
Cdd:MTH00176   1 MLVDLFSSFDPPNKNIFSMISLSWITLLLfLLLMPSSVWFcPSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISLFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  79 FLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALG 158
Cdd:MTH00176  81 LVMSLNLSGLIPYVFTSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQGTPPLLNPFLVLIELVSLLIRPLTLA 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 299825766 159 VRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQEN 226
Cdd:MTH00176 161 VRLAANLSAGHLLLGLLGAAMWGLLPVSPLIGFLLLIVQILYFMFEIAVCMIQAYVFTLLLSLYLDEH 228
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 1-225 3.95e-42

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 142.31  E-value: 3.95e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILP-WILYPTPTSRWIN-NRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMI 78
Cdd:MTH00173   1 MMVDLFSSFDDHNSSFSSLSFLMWLLSlMSLFFFSSSVWVSsSNLSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  79 FLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALG 158
Cdd:MTH00173  81 FLISLNLSGLLPFVFSVTSHLAFTFSLALPLWLSLILSGLFYNPSKSLAGLVPAGAPAGLNPFLVLIETVSILIRPLTLT 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 299825766 159 VRLTANLTAGHLLIQLIA-TAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:MTH00173 161 VRLLANISAGHIVLTLIGnYLSSSLFSSSVVSLLLVLLIQVGYFIFEVAVMLIQAYIFTLLIKLYSDE 228
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 66-224 3.80e-41

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 137.53  E-value: 3.80e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  66 GHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIII 145
Cdd:cd00310    1 GKKYLPLLGTLFLFILFSNLLGLIPYSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFLPPGTPLPLAPLMVPI 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 299825766 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILtatVLFLLTLLEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:cd00310   81 ELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSVGLLPLL---LPVALTLLELFVAFIQAYVFTLLTAVYIS 156
ATP-synt_A pfam00119
ATP synthase A chain;
19-224 2.25e-36

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 127.22  E-value: 2.25e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   19 LIAVAIILPWILYPTP-TSRWINNRLLTLQGWFINRLSQQIFLPI-NQGGHKWAVLLTSLMIFLITLNMLGLL---PYTF 93
Cdd:pfam00119   5 LIVALILLLFLLLATRkTKKLVPGRLQNFVEMLVEFVDNIVKDNIgKKKGRKFFPLLLTLFFFILVSNLLGLIpksPGGF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   94 TPTTQLSLNMAFAVPLWLATVIIGMRNQPTAA-LGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLI 172
Cdd:pfam00119  85 TVTADINVTLALALIVFLLVHYYGIKKHGLGGyFKKLFVPPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLLL 164

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 299825766  173 QLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:pfam00119 165 LLLAGLIFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 4-222 3.96e-34

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 121.76  E-value: 3.96e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   4 SFFDQFMSPTYMGIPLIAVAIILPWILYPTPTSRWI-NNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFLIT 82
Cdd:MTH00005   7 SSFDPATNSLFNNLSSTAFWAFNFSIILLLSSSFWItPNRLSSIMSPPKSTMHTQLSRTFGKHLKGFSSLISALFTMIIL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  83 LNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALGVRLT 162
Cdd:MTH00005  87 MNLSGLLPYVFSTSSHLIFTLTLGLPLWLSLIMSSVTFSPKKFAAHLLPGGAPDWLNPFLVLIETISILVRPITLSFRLA 166

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 163 ANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLY 222
Cdd:MTH00005 167 ANMSAGHIVLSLIGIYAASALFSSISSTILLILTQMGYILFEVGICLIQAYIFCLLLSLY 226
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 1-223 9.80e-32

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 115.52  E-value: 9.80e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766   1 MMLSFFDQFMSPTYMGIPLIAVAIILPW--ILYPTPTSRWINNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMI 78
Cdd:MTH00172   1 MSSSYFDQFNIVWLIGLTNSSIMMILVIivVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  79 FLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETISLFIRPLALG 158
Cdd:MTH00172  81 FIVFLNLLGLFPYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRFKWDFFSILMPSGAPLGLAPLLVLIETVSYISRAISLG 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 299825766 159 VRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYL 223
Cdd:MTH00172 161 VRLAANLSAGHLLFAILAGFGFNMLCASGFLSLFPLLIMVFITLLEIAVAVIQAYVFCLLTTIYL 225
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 66-227 7.90e-28

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 105.86  E-value: 7.90e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  66 GHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIII 145
Cdd:MTH00175  79 GQKYFPFILSLFLFIAILNILGLFPYVFTPTAHIIITFGLSLSIIIAVTLLGFLTFKWNFLSILMPGGAPLVLAPFLVLI 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 146 ETISLFIRPLALGVRLTANLTAGHLLIQLIATAAF-VLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYLQ 224
Cdd:MTH00175 159 ETLSYLIRAISLGVRLAANISAGHLLFAILSGFAFnMLSNGLIILSLFPMLIMIFITLLEMAVAVIQAYVFCLLTTIYLG 238


                 ...
gi 299825766 225 ENV 227
Cdd:MTH00175 239 DTI 241
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 49-225 9.39e-26

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 99.38  E-value: 9.39e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  49 WFINRLSQQIFLPINQGGHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAA-LG 127
Cdd:COG0356   37 MLVEFVRNQVKDTIGKKGRKFAPLLLTLFLFILVSNLLGLIPGLFPPTADINVTLALALIVFVLVHYYGIKKKGLGGyLK 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 128 HLLPEGTPtPLIPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLplmptVAILTATVLFLLTLLEVAV 207
Cdd:COG0356  117 HLFFPPFP-WLAPLMLPIEIISELARPLSLSLRLFGNMFAGHIILLLLAGLAPFLL-----LGVLSLLLPVAWTAFELLV 190

                        170
                 ....*....|....*...
gi 299825766 208 AMIQAYVFVLLLSLYLQE 225
Cdd:COG0356  191 GFLQAYIFTMLTAVYISL 208
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 62-225 5.95e-23

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 92.55  E-value: 5.95e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  62 INQGGHKWAVLLTSLMIFLITLNMLGLLP-YTFTPTTQLSLNMAFAVPLWLATVIIGMRNQptaALGHLLPEGTPTPlIP 140
Cdd:PRK05815  65 IGGKGKKFAPLAFTLFLFILLMNLLGLIPyLLFPPTADINVTLALALIVFVLVIYYGIKKK---GLGGYLKEFYLQP-HP 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 141 VLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTatvlFLLTLLEVAVAMIQAYVFVLLLS 220
Cdd:PRK05815 141 LLLPIEIISEFSRPISLSLRLFGNMLAGELILALIALLGGAGLLLALAPLILP----VAWTIFEIFVGTLQAYIFMMLTI 216


                 ....*
gi 299825766 221 LYLQE 225
Cdd:PRK05815 217 VYISM 221
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 63-227 1.73e-19

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 83.84  E-value: 1.73e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  63 NQGGHKWAVLLtSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVL 142
Cdd:MTH00174  85 NKGGNYLAFVL-SLFILILFGNGLGLFPYVFTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFSILMPQGAPLALAPLL 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 143 IIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTV-AILTATVLFLLTLLEVAVAMIQAYVFVLLLSL 221
Cdd:MTH00174 164 TIIETLSYISRAISLGVRLAANISSGHLLFSIIASFAWKMINTGILIgSFVPFAILIFVTILEMAVAIIQAYVFTLLTIV 243


                 ....*.
gi 299825766 222 YLQENV 227
Cdd:MTH00174 244 YLRDTV 249
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 62-223 2.12e-18

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 82.10  E-value: 2.12e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  62 INQGGHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPV 141
Cdd:PRK13419 163 IGHGYEKFLPYLLTVFFFILVCNLLGLVPYGATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLWII 242

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766 142 LIIIETISLFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMPTVAILTATVLFLLtLLEVAVAMIQAYVFVLLLSL 221
Cdd:PRK13419 243 MIPIEFIGLFTKPFALTVRLFANMTAGHIVILSLIFISFILKSYIVAVAVSVPFAIFIY-LLELFVAFLQAYIFTMLSAL 321


                 ..
gi 299825766 222 YL 223
Cdd:PRK13419 322 FI 323
ATP6 MTH00087
ATP synthase F0 subunit 6; Provisional
 71-225 4.09e-14

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177152  Cd Length: 195  Bit Score: 68.08  E-value: 4.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  71 VLLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQptAALGHLLPEGTPTPLIP-VLIIIETIS 149
Cdd:MTH00087  53 VISFFTFIVLLLFCFGGLFPYSFSPCGMVEFTFLYALVAWLSTFLSFLSKS--EKFSVYLSKGSDSFLKTfSMLFVEIVS 130

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 299825766 150 LFIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPLMptvailtatvlFLLTLLEVAVAMIQAYVFVLLLSLYLQE 225
Cdd:MTH00087 131 ELSRPLALTLRLTVNLMVGHLISSLLNFLGEKYVWLS-----------ILAIMMECFVAFIQSYIFSRLIYLYLNE 195
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 94-223 3.30e-10

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 58.75  E-value: 3.30e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  94 TPTTQLSLNMAFAVPLWLATVIIGMRNQPTAALGHLLPEGTPTPLIPVLIIIETI-SLFIRPLALGVRLTANLTAGHLLI 172
Cdd:PRK13417 217 TVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGVPLLLYPIMWPLEFIvSPMAKTFALTVRLLANMTAGHVII 296

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 299825766 173 qlIATAAFVLLPLMPTVAILTATVLFLLTLLEVAVAMIQAYVFVLLLSLYL 223
Cdd:PRK13417 297 --LALMGFIFQFQSWGIVPVSVIGSGLIYVLEIFVAFLQAYIFVLLTSLFV 345
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 19-218 5.50e-06

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 45.84  E-value: 5.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  19 LIAVAIILPWILYPTPTSRwiNNRLLTLQGWFINRLSQQIFLPINQGGHKWAVLLTSLMIFLITLNMLGLLPYTFTPTTQ 98
Cdd:PRK13421  29 IMAVLAAGSALATRRLSLA--PGRLQSVLELVVTTIDAQIRDTMQTDPAPYRALIGTLFLFVLVANWSSLVPGVEPPTAH 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  99 LSLNMAFAVPLWLATVIIGMRNQptAALGHLLPEGTPTPLIPVLIIIETISlfiRPLALGVRLTANLTAGHLLIQLIATA 178
Cdd:PRK13421 107 LETDAALALIVFLATIYYGVRAR--GVRGYLATFAEPTWVMIPLNLVEQLT---RTFSLIVRLFGNVMSGVFVIGIVLSL 181

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 299825766 179 A--FVLLPLMPtvailtatvlflltlLEVAVAMIQAYVFVLL 218
Cdd:PRK13421 182 AglLVPIPLMA---------------LDLLTGAVQAYIFAVL 208
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 72-223 2.05e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 43.96  E-value: 2.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 299825766  72 LLTSLMIFLITLNMLGLLPYTFTPTTQLSLNMAFAVPLWLATVIIGMRNQP-TAALGHLLpegTPTpliPVLIIIETISL 150
Cdd:PRK13420  77 FVGTLWIFILVANLIGLIPGFHSPTADLSVTAALALLVFFSVHWFGIRAEGlREYLKHYL---SPS---PFLLPFHLISE 150

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 299825766 151 FIRPLALGVRLTANLTAGHLLIQLIATAAFVLLPlmptVAILtatvlflltLLEVAVAMIQAYVFVLLLSLYL 223
Cdd:PRK13420 151 ITRTLALAVRLFGNIMSLELAALLVLLVAGFLVP----VPIL---------MLHIIEALVQAYIFGMLALIYI 210
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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