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Conserved domains on  [gi|312164873|ref|YP_003896058|]
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RNA-dependent RNA polymerase [Great Island virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Orbi_VP1 super family cl12314
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 40-1266 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


The actual alignment was detected with superfamily member pfam05788:

Pssm-ID: 461740  Cd Length: 1297  Bit Score: 812.79  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873    40 QHSENEKRGYLYTVPVVRENGWQEIPRCVGARPRdALDVYYRSIQPISRIQPEEEFLRNYALDDGMES----DLYRFMQH 115
Cdd:pfam05788   55 QAEEILRKISLRKERLYGIPVLDEVEWKYVFDGQ-TFQSYAFEVYVNSILPWSELDPEEEFLRNYRVSrektEVEKFIEF 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   116 RAREEMAVYGDMALRHWYALVQQLADDFGIVPLGLSCMERFIDENGDPFHQSTRDLSKISDEVRSSSVVLLFEMSICEAL 195
Cdd:pfam05788  134 RAKNEMQIYGDIPIKVWCCFINELSIELGMQPLGMQVMADFVNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESI 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   196 LEYNVTLRSRESNITpTVRVGRLEIDRIEIIRELYTLMLPHPKKICNMLRASYSWFVKNWGIAASEVTLLESTAGDDRNS 275
Cdd:pfam05788  214 LEFNIKMRMREEEIS-ALEFGDVKLDPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   276 KDVTYQRWRRIRNPYRDiilgtrFHRESLAANLKKVDEAVEYARSLANTPVSLSLFRTLMHDTYTQEFDPQNQGHVQLAS 355
Cdd:pfam05788  293 KDVFYDKFRTEPNRYKA------LFRSSFYNESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSN 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   356 LLLAVQTMAGYGRAWVVNASDDPERMLQPTKDNFVERVSRETERFFVNAYEEARVHGFDIIPPEDMYTSLLRLAKNTSSG 435
Cdd:pfam05788  367 MILASFLLSIQTITGYGRAWVKNVSTEFDKQLKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLAR 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   436 FSTEVEVRKSYGPKAaRREELVRVRSRQKALYLLREGHNIYSPHMMQMRYDSPECFQTRGTRDVPIKATRTIYAINVNVL 515
Cdd:pfam05788  447 NTSSGFSTEIYVKKR-FGPRLRDKDLRKINSRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSI 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   516 APQHILTLPLNEYFARAGGPTHPSVASIGGKVIIGDLEATGSRVMDAA-----DTFRNTADSAIWTLALDYSNYDTHMTQ 590
Cdd:pfam05788  526 NLSVLVPQLIVTLPLNEYFSRVGGITKPDYKKIGGKVIVGDLEATGSRvmdaaDCFRNSADRDIFTIAIDYSEYDTHLTR 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   591 HNFRRGMIAGIRSAIARHHALRYGQWDVFQLLEAGYGEGRVANTLWNGKRRVLRMDATAYEALPEAERTVppdapfrfrP 670
Cdd:pfam05788  606 HNFRTGMLQGIREAMAPYRGLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDK---------G 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   671 PGTHPIRTLSLAAPATGNNV-------VLVVPWDGSDLARVSTHLSGENSTLVANSLHNMAMGRVIQDEVQARAPGVFEV 743
Cdd:pfam05788  677 SFKVPKGVLPVSSVDVANRIavdkgfdTLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTF 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   744 LSEMYVGDDTLHYIRMLTLRPEHVDRAIDVIFKTIELCGHEASASKTTFAPFSAEKTQTHAKQGIYIPQDRMMIISSERR 823
Cdd:pfam05788  757 LSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERR 836

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   824 KEIENVAGYMRAQVTTFVTKVSRGFSEDLAHRILLFKSALVGYRRMKATIREGSVYRRRNFHSH-EDGYTLCRVYDPTIL 902
Cdd:pfam05788  837 KDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFDSNdEDGFTLIQIRNPLAL 916

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   903 YAPIDSGGYGVHPFALNVVQTRELHLDSQQLFPVYRDLVARRVIMDAFPPSWNESDVDTRLISTKTPMGLFSKIVRQTPR 982
Cdd:pfam05788  917 YVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQ 996

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   983 LALTDPELMALVDQLPLGEHSPTRLSSTMMRGALLKEPRARTLLSPAYEEQFSKTLSSWREPVEFSPIgqheVTSAYAKV 1062
Cdd:pfam05788  997 AALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKESSASGLLSSGYKLEYQKALNVWIRQVSMRLG----EESGVIST 1072

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873  1063 LDLRVEKR--EAPIPF----FPDQNLSPGFLAQKMYVGHRTTTRPLRSYVDQIDRILRGDTVMRGILTSSAIMSLLEKIG 1136
Cdd:pfam05788 1073 SYAKLFDVyfEGELDGapqmFPDQNLSPQFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLG 1152

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873  1137 FDHDPTDLATVFELLNLEPRVARRLAEFVTSDRLRFDVHLLNRRGIGGDEFSMSLDVCTEGSRDERIDCPPEFTPVERDA 1216
Cdd:pfam05788 1153 TNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDA 1232

                         1210      1220      1230      1240      1250
                   ....*....|....*....|....*....|....*....|....*....|
gi 312164873  1217 VSLHGEQIQMLYAShfgSSCRVVFQVRPEHRSALRRIRVKMRAPRQRIVR 1266
Cdd:pfam05788 1233 ISLYCTQMAMLRAA---LGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPK 1279
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 40-1266 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 812.79  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873    40 QHSENEKRGYLYTVPVVRENGWQEIPRCVGARPRdALDVYYRSIQPISRIQPEEEFLRNYALDDGMES----DLYRFMQH 115
Cdd:pfam05788   55 QAEEILRKISLRKERLYGIPVLDEVEWKYVFDGQ-TFQSYAFEVYVNSILPWSELDPEEEFLRNYRVSrektEVEKFIEF 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   116 RAREEMAVYGDMALRHWYALVQQLADDFGIVPLGLSCMERFIDENGDPFHQSTRDLSKISDEVRSSSVVLLFEMSICEAL 195
Cdd:pfam05788  134 RAKNEMQIYGDIPIKVWCCFINELSIELGMQPLGMQVMADFVNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESI 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   196 LEYNVTLRSRESNITpTVRVGRLEIDRIEIIRELYTLMLPHPKKICNMLRASYSWFVKNWGIAASEVTLLESTAGDDRNS 275
Cdd:pfam05788  214 LEFNIKMRMREEEIS-ALEFGDVKLDPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   276 KDVTYQRWRRIRNPYRDiilgtrFHRESLAANLKKVDEAVEYARSLANTPVSLSLFRTLMHDTYTQEFDPQNQGHVQLAS 355
Cdd:pfam05788  293 KDVFYDKFRTEPNRYKA------LFRSSFYNESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSN 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   356 LLLAVQTMAGYGRAWVVNASDDPERMLQPTKDNFVERVSRETERFFVNAYEEARVHGFDIIPPEDMYTSLLRLAKNTSSG 435
Cdd:pfam05788  367 MILASFLLSIQTITGYGRAWVKNVSTEFDKQLKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLAR 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   436 FSTEVEVRKSYGPKAaRREELVRVRSRQKALYLLREGHNIYSPHMMQMRYDSPECFQTRGTRDVPIKATRTIYAINVNVL 515
Cdd:pfam05788  447 NTSSGFSTEIYVKKR-FGPRLRDKDLRKINSRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSI 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   516 APQHILTLPLNEYFARAGGPTHPSVASIGGKVIIGDLEATGSRVMDAA-----DTFRNTADSAIWTLALDYSNYDTHMTQ 590
Cdd:pfam05788  526 NLSVLVPQLIVTLPLNEYFSRVGGITKPDYKKIGGKVIVGDLEATGSRvmdaaDCFRNSADRDIFTIAIDYSEYDTHLTR 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   591 HNFRRGMIAGIRSAIARHHALRYGQWDVFQLLEAGYGEGRVANTLWNGKRRVLRMDATAYEALPEAERTVppdapfrfrP 670
Cdd:pfam05788  606 HNFRTGMLQGIREAMAPYRGLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDK---------G 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   671 PGTHPIRTLSLAAPATGNNV-------VLVVPWDGSDLARVSTHLSGENSTLVANSLHNMAMGRVIQDEVQARAPGVFEV 743
Cdd:pfam05788  677 SFKVPKGVLPVSSVDVANRIavdkgfdTLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTF 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   744 LSEMYVGDDTLHYIRMLTLRPEHVDRAIDVIFKTIELCGHEASASKTTFAPFSAEKTQTHAKQGIYIPQDRMMIISSERR 823
Cdd:pfam05788  757 LSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERR 836

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   824 KEIENVAGYMRAQVTTFVTKVSRGFSEDLAHRILLFKSALVGYRRMKATIREGSVYRRRNFHSH-EDGYTLCRVYDPTIL 902
Cdd:pfam05788  837 KDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFDSNdEDGFTLIQIRNPLAL 916

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   903 YAPIDSGGYGVHPFALNVVQTRELHLDSQQLFPVYRDLVARRVIMDAFPPSWNESDVDTRLISTKTPMGLFSKIVRQTPR 982
Cdd:pfam05788  917 YVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQ 996

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   983 LALTDPELMALVDQLPLGEHSPTRLSSTMMRGALLKEPRARTLLSPAYEEQFSKTLSSWREPVEFSPIgqheVTSAYAKV 1062
Cdd:pfam05788  997 AALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKESSASGLLSSGYKLEYQKALNVWIRQVSMRLG----EESGVIST 1072

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873  1063 LDLRVEKR--EAPIPF----FPDQNLSPGFLAQKMYVGHRTTTRPLRSYVDQIDRILRGDTVMRGILTSSAIMSLLEKIG 1136
Cdd:pfam05788 1073 SYAKLFDVyfEGELDGapqmFPDQNLSPQFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLG 1152

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873  1137 FDHDPTDLATVFELLNLEPRVARRLAEFVTSDRLRFDVHLLNRRGIGGDEFSMSLDVCTEGSRDERIDCPPEFTPVERDA 1216
Cdd:pfam05788 1153 TNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDA 1232

                         1210      1220      1230      1240      1250
                   ....*....|....*....|....*....|....*....|....*....|
gi 312164873  1217 VSLHGEQIQMLYAShfgSSCRVVFQVRPEHRSALRRIRVKMRAPRQRIVR 1266
Cdd:pfam05788 1233 ISLYCTQMAMLRAA---LGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPK 1279
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 40-1266 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 812.79  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873    40 QHSENEKRGYLYTVPVVRENGWQEIPRCVGARPRdALDVYYRSIQPISRIQPEEEFLRNYALDDGMES----DLYRFMQH 115
Cdd:pfam05788   55 QAEEILRKISLRKERLYGIPVLDEVEWKYVFDGQ-TFQSYAFEVYVNSILPWSELDPEEEFLRNYRVSrektEVEKFIEF 133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   116 RAREEMAVYGDMALRHWYALVQQLADDFGIVPLGLSCMERFIDENGDPFHQSTRDLSKISDEVRSSSVVLLFEMSICEAL 195
Cdd:pfam05788  134 RAKNEMQIYGDIPIKVWCCFINELSIELGMQPLGMQVMADFVNRFQSPFHQGNRDLSNLEDFQVAYTTPLLFEMCCMESI 213

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   196 LEYNVTLRSRESNITpTVRVGRLEIDRIEIIRELYTLMLPHPKKICNMLRASYSWFVKNWGIAASEVTLLESTAGDDRNS 275
Cdd:pfam05788  214 LEFNIKMRMREEEIS-ALEFGDVKLDPVGLLREFFILCLPHPKKINNVLRAPYSWFVKMWGVGADPIVVLQSTAGDDRNS 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   276 KDVTYQRWRRIRNPYRDiilgtrFHRESLAANLKKVDEAVEYARSLANTPVSLSLFRTLMHDTYTQEFDPQNQGHVQLAS 355
Cdd:pfam05788  293 KDVFYDKFRTEPNRYKA------LFRSSFYNESRRMNEEKILEAVKYSQDLGSHDRRLPLFEKMLKPVYTTPFYPHKSSN 366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   356 LLLAVQTMAGYGRAWVVNASDDPERMLQPTKDNFVERVSRETERFFVNAYEEARVHGFDIIPPEDMYTSLLRLAKNTSSG 435
Cdd:pfam05788  367 MILASFLLSIQTITGYGRAWVKNVSTEFDKQLKPNPSNLVLDVSDLTREFFKQAYVEAKERREEDVKPEDLYTSMLRLAR 446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   436 FSTEVEVRKSYGPKAaRREELVRVRSRQKALYLLREGHNIYSPHMMQMRYDSPECFQTRGTRDVPIKATRTIYAINVNVL 515
Cdd:pfam05788  447 NTSSGFSTEIYVKKR-FGPRLRDKDLRKINSRIKALVIFTKGHTVFTDEELHKKYNSVELYQTKGSRDVPIKATRTIYSI 525

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   516 APQHILTLPLNEYFARAGGPTHPSVASIGGKVIIGDLEATGSRVMDAA-----DTFRNTADSAIWTLALDYSNYDTHMTQ 590
Cdd:pfam05788  526 NLSVLVPQLIVTLPLNEYFSRVGGITKPDYKKIGGKVIVGDLEATGSRvmdaaDCFRNSADRDIFTIAIDYSEYDTHLTR 605

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   591 HNFRRGMIAGIRSAIARHHALRYGQWDVFQLLEAGYGEGRVANTLWNGKRRVLRMDATAYEALPEAERTVppdapfrfrP 670
Cdd:pfam05788  606 HNFRTGMLQGIREAMAPYRGLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDAYIRLDESERDK---------G 676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   671 PGTHPIRTLSLAAPATGNNV-------VLVVPWDGSDLARVSTHLSGENSTLVANSLHNMAMGRVIQDEVQARAPGVFEV 743
Cdd:pfam05788  677 SFKVPKGVLPVSSVDVANRIavdkgfdTLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLGQRQVGREQPGSLTF 756

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   744 LSEMYVGDDTLHYIRMLTLRPEHVDRAIDVIFKTIELCGHEASASKTTFAPFSAEKTQTHAKQGIYIPQDRMMIISSERR 823
Cdd:pfam05788  757 LSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAKQGCYVPQDRMMIISSERR 836

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   824 KEIENVAGYMRAQVTTFVTKVSRGFSEDLAHRILLFKSALVGYRRMKATIREGSVYRRRNFHSH-EDGYTLCRVYDPTIL 902
Cdd:pfam05788  837 KDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFDSNdEDGFTLIQIRNPLAL 916

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   903 YAPIDSGGYGVHPFALNVVQTRELHLDSQQLFPVYRDLVARRVIMDAFPPSWNESDVDTRLISTKTPMGLFSKIVRQTPR 982
Cdd:pfam05788  917 YVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGLISATKKSFFSKMARPAVQ 996

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873   983 LALTDPELMALVDQLPLGEHSPTRLSSTMMRGALLKEPRARTLLSPAYEEQFSKTLSSWREPVEFSPIgqheVTSAYAKV 1062
Cdd:pfam05788  997 AALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKESSASGLLSSGYKLEYQKALNVWIRQVSMRLG----EESGVIST 1072

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873  1063 LDLRVEKR--EAPIPF----FPDQNLSPGFLAQKMYVGHRTTTRPLRSYVDQIDRILRGDTVMRGILTSSAIMSLLEKIG 1136
Cdd:pfam05788 1073 SYAKLFDVyfEGELDGapqmFPDQNLSPQFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRGFITANTILNVIEKLG 1152

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 312164873  1137 FDHDPTDLATVFELLNLEPRVARRLAEFVTSDRLRFDVHLLNRRGIGGDEFSMSLDVCTEGSRDERIDCPPEFTPVERDA 1216
Cdd:pfam05788 1153 TNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDTYLAYPYQLTKTEVDA 1232

                         1210      1220      1230      1240      1250
                   ....*....|....*....|....*....|....*....|....*....|
gi 312164873  1217 VSLHGEQIQMLYAShfgSSCRVVFQVRPEHRSALRRIRVKMRAPRQRIVR 1266
Cdd:pfam05788 1233 ISLYCTQMAMLRAA---LGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPK 1279
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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