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Conserved domains on  [gi|46358646|ref|YP_006421|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Eudromia elegans]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 6.30e-54

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 168.77  E-value: 6.30e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVQYGVGFM-MIVLVGVVLGGFVEEGVVVGGTVDSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVlVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 46358646  160 ELVRGVSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 6.30e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 168.77  E-value: 6.30e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVQYGVGFM-MIVLVGVVLGGFVEEGVVVGGTVDSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVlVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 46358646  160 ELVRGVSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 6.87e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.04  E-value: 6.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    17 LAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSL-AADPYPEAWGDWRVVQYGVGFM 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 46358646    96 MIVLVGVVLGGFVEEGVVVGGTVDSVGmmsvRMDFSGVAMFYfWGAGLFMVVGWGLLLSLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFT-DYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 6.30e-54

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 168.77  E-value: 6.30e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVQYGVGFM-MIVLVGVVLGGFVEEGVVVGGTVDSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVL 159
Cdd:MTH00115  81 AWGDWGVVGYVVGFVlVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 46358646  160 ELVRGVSRGAIRAV 173
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.30e-53

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 166.85  E-value: 3.30e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVQYGVGFMMIVLVGVVLGGFVEEGVVVGGTVDSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVLE 160
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 46358646  161 LVRGVSRGAIRAV 173
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 7.96e-49

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 155.78  E-value: 7.96e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVQYGVGFMMIVLVGVVLGGfVEEGVVVGGTVDSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVLE 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFG-CNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                        170
                 ....*....|...
gi 46358646  161 LVRGVSRGAIRAV 173
Cdd:MTH00065 160 VTRGLSRGSLRAV 172
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-164 2.03e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 101.03  E-value: 2.03e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVQYGVGFMMIVLVGVVLGGFVEEGVVVGGTV---------DSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGL 151
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 46358646  152 LLSLFVVLELVRG 164
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 2.31e-26

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 98.14  E-value: 2.31e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVvqygVGFMMIVLVGVVLGGFVEEGVVVGGTVDSVGMMSvRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVLE 160
Cdd:MTH00214  81 SWGGWSV----LLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEAN-NLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                        170
                 ....*....|...
gi 46358646  161 LVRGVSRGAIRAV 173
Cdd:MTH00214 156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-172 6.34e-16

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 70.70  E-value: 6.34e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    1 MTYFVFFLgvgLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00045   2 VFYLFLIL---MLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646   81 AWGDWRVVqyGVGFMMIVLVGVVLGGFVEEGVvvggtvdSVGMMSVRMDFSGVAMFYFWGAGLFMVVGWGLLLSLFVVLE 160
Cdd:MTH00045  79 VSNLGEVL--VLSLLLSLWVFISFDNFLELSN-------NNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALV 149

                        170
                 ....*....|..
gi 46358646  161 LVRGVSRGAIRA 172
Cdd:MTH00045 150 ISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-161 6.87e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.04  E-value: 6.87e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46358646    17 LAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSL-AADPYPEAWGDWRVVQYGVGFM 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 46358646    96 MIVLVGVVLGGFVEEGVVVGGTVDSVGmmsvRMDFSGVAMFYfWGAGLFMVVGWGLLLSLFVVLEL 161
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVG----NIEAIGELLFT-DYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 7-73 7.38e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 35.47  E-value: 7.38e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 46358646    7 FLGVGLVMGALAVACNPSPYYGVLGLVLGSVMGCGWLVSLGVSFVSLVLFLVYLGGMLVVFVYSVSL 73
Cdd:MTH00021   1 FFSLGIIGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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