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Conserved domains on  [gi|476409109|ref|YP_007626743|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Tragelaphus strepsiceros]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 1.08e-96

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 277.07  E-value: 1.08e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   1 MMTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  81 EVWVSNKVVLGAFVTGLLMELLMVFYVLKEKEVEIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....*
gi 476409109 161 LFIGVVVIMEITRGN 175
Cdd:MTH00109 161 LFIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 1.08e-96

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 277.07  E-value: 1.08e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   1 MMTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  81 EVWVSNKVVLGAFVTGLLMELLMVFYVLKEKEVEIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....*
gi 476409109 161 LFIGVVVIMEITRGN 175
Cdd:MTH00109 161 LFIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 6.33e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 62.52  E-value: 6.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   18 VGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPEVWVSNKVVLGAFVTGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 476409109   98 LMELLMVFYVLKEKEVEIVfefnglgdwviyDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLFIGVVVIMEI 171
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAA------------AAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-175 1.08e-96

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 277.07  E-value: 1.08e-96
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   1 MMTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00109   1 MMMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  81 EVWVSNKVVLGAFVTGLLMELLMVFYVLKEKEVEIVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00109  81 ETWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWS 160

                        170
                 ....*....|....*
gi 476409109 161 LFIGVVVIMEITRGN 175
Cdd:MTH00109 161 LFIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 2-174 8.12e-35

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 119.86  E-value: 8.12e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   2 MTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  82 VWVSNKVVlgafvtgllmeLLMVFYVLKEKEVEIVFefngLGDW------VIYDTGDSGFFSEEAMGIAALYSYGTWLVI 155
Cdd:MTH00138  81 SWGSWSVL-----------GYVVGYLVGVVLAAGLF----WGGWyegswvVVDELKEFSVLRGDVGGVALMYSSGGGMLV 145

                        170
                 ....*....|....*....
gi 476409109 156 VTGWSLFIGVVVIMEITRG 174
Cdd:MTH00138 146 ICAWVLLLTLFVVLELTRG 164
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 2-174 1.38e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 109.17  E-value: 1.38e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   2 MTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  82 VWVSNKVVLGAFVTGLLMELLMVFyvlkekeveiVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYIL----------FGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                        170
                 ....*....|...
gi 476409109 162 FIGVVVIMEITRG 174
Cdd:MTH00065 151 LLTLFVVLEVTRG 163
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 2-174 4.05e-25

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 95.20  E-value: 4.05e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   2 MTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  82 VWVSNKVVLGAFVTGLLMELLMVFYVlkekeveIVFEFNGLGDWVIyDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVG-------GLWGMEGVGVVTV-DSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                        170
                 ....*....|...
gi 476409109 162 FIGVVVIMEITRG 174
Cdd:MTH00115 153 LLTLFVVLELVRG 165
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 2-174 6.79e-17

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 73.48  E-value: 6.79e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   2 MTYIVFILSIIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPE 81
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  82 VWVSNKVVLGAFVTGLLMELLMVFYvlkekeveivfefnGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSL 161
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYF--------------YGGWEMLSWMGVDEANNLDLSGVSDLYSRGFFLLLLGGVVL 146

                        170
                 ....*....|...
gi 476409109 162 FIGVVVIMEITRG 174
Cdd:MTH00214 147 FLVLFVVLELVRG 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-175 3.64e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 66.47  E-value: 3.64e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   1 MMTYIVFILsIIFVMGFVGFSSkpSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYP 80
Cdd:MTH00045   1 MVFYLFLIL-MLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109  81 EVWVSNKVVLGAFVTGLLmellmvfyvlkekeveIVFEFNGLGDWVIYDTGDSGFFSEeaMGIAALYSYGTWLVIVTGWS 160
Cdd:MTH00045  78 SVSNLGEVLVLSLLLSLW----------------VFISFDNFLELSNNNWSLVSLSDL--VGSSELYNSGGLYLLLGGFI 139

                        170
                 ....*....|....*
gi 476409109 161 LFIGVVVIMEITRGN 175
Cdd:MTH00045 140 LLVALVVALVISFGH 154
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
18-171 6.33e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 62.52  E-value: 6.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   18 VGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPEVWVSNKVVLGAFVTGL 97
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 476409109   98 LMELLMVFYVLKEKEVEIVfefnglgdwviyDTGDSGFFSEEAMGIaALYSYGTWLVIVTGWSLFIGVVVIMEI 171
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAA------------AAAAPDVGNIEAIGE-LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-128 6.46e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 38.33  E-value: 6.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   1 MMTYIVFILSIIFVMGFVGFSSkpsPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATeQYP 80
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSKQ---PLSLGLVLLLLSLFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSP-NPL 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 476409109  81 EVWVSNKVVLGAFVTGLLMELLMVFYVLKEKEVEIVFEFNGLGDWVIY 128
Cdd:MTH00152  77 FGSNFKFVFFSLTLFGFLGLFFFFLYLYSSGGLSLSSLFDGSSGSLSF 124
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 8-120 6.15e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 35.37  E-value: 6.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 476409109   8 ILSIIFVMGFVgFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMAteqyPEVWVSNK 87
Cdd:MTH00212   6 LLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS----PNEHLFFK 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 476409109  88 VVLGAFVTGLLMeLLMVFYVLKEKEVEIVFEFN 120
Cdd:MTH00212  81 KYFKGFGMILIS-LNLYLLLMTLGSSNFSPMLN 112
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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