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Conserved domains on  [gi|722491015|ref|YP_009107965|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Drepanis coccinea]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.47e-37

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 126.79  E-value: 1.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVSWGVVGYGFGMGFVVLVGLAVGGALGLLGGDG--TVNNGGLLSVRSDFSGVAVLYSEGVGLLLIGGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGvvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 722491015 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.47e-37

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 126.79  E-value: 1.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVSWGVVGYGFGMGFVVLVGLAVGGALGLLGGDG--TVNNGGLLSVRSDFSGVAVLYSEGVGLLLIGGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGvvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 722491015 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-96 5.90e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 38.25  E-value: 5.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   17 LAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSL-AADPYPESWVSWGVVGYGFGMG 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80


                  .
gi 722491015   96 F 96
Cdd:pfam00499  81 L 81
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.47e-37

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 126.79  E-value: 1.47e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVSWGVVGYGFGMGFVVLVGLAVGGALGLLGGDG--TVNNGGLLSVRSDFSGVAVLYSEGVGLLLIGGWGLLLTLFVVL 158
Cdd:MTH00115  81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWGMEGVGvvTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 722491015 159 ELVRGLSRGAIRAV 172
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 7.14e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 122.56  E-value: 7.14e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVSWGVVGYGFGMGFVVLVGLAVGGALGLLGGDGTVNNGGLLSV-RSDFSGVAVLYSEGVGLLLIGGWGLLLTLFVVLE 159
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVlRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                        170
                 ....*....|...
gi 722491015 160 LVRGLSRGAIRAV 172
Cdd:MTH00138 161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 1.72e-34

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 119.18  E-value: 1.72e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVSWGVVGYGFGMGFVVLVGLAVGGALGLLGGDGTVNNGGLLSVRSDFSGVAVLYSEGVGLLLIGGWGLLLTLFVVLEL 160
Cdd:MTH00065  81 AWGSWSVLVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEV 160

                        170
                 ....*....|..
gi 722491015 161 VRGLSRGAIRAV 172
Cdd:MTH00065 161 TRGLSRGSLRAV 172
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.21e-16

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 72.71  E-value: 1.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVSWGVVGYGFGMGFVVLVGLAVGGALGLLGGDGTVNNGGLLSVrsdfSGVAVLYSEGVGLLLIGGWGLLLTLFVVLEL 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLEL 156

                        170
                 ....*....|..
gi 722491015 161 VRGLSRGAIRAV 172
Cdd:MTH00214 157 VRGLSRGALRVV 168
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-163 2.35e-16

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 72.14  E-value: 2.35e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   1 MMEFVLFLGVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  81 SWVS----WGVVGYGFGMGFVVLVGLAVGGALGLLGGDGTVNN------GGLLSVRSDFSGVAVLYSEGVGLLLIGGWGL 150
Cdd:MTH00109  82 TWVSnkvvLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDwviydtGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|...
gi 722491015 151 LLTLFVVLELVRG 163
Cdd:MTH00109 162 FIGVFVIIEITRG 174
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 2-171 6.69e-10

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 54.91  E-value: 6.69e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   2 MEFVLFLgVCFALGGLAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSLAADPYPES 81
Cdd:MTH00045   1 MVFYLFL-ILMLFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPSV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015  82 wvswgvvgYGFGMGFVVLVGLAVGGALGLLGGDGTVNNGGLLSVRSDFSGVAVLYSEGVGLLLIGGWGLLLTLFVVLELV 161
Cdd:MTH00045  80 --------SNLGEVLVLSLLLSLWVFISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVIS 151

                        170
                 ....*....|
gi 722491015 162 RGLSRGAIRA 171
Cdd:MTH00045 152 FGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-96 5.90e-04

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 38.25  E-value: 5.90e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 722491015   17 LAVASNPSPYYGVLGLVIAAVAGCGWLVSLGVSFVSLVLVMV*LGGMLVVFVYSVSL-AADPYPESWVSWGVVGYGFGMG 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80


                  .
gi 722491015   96 F 96
Cdd:pfam00499  81 L 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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