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Conserved domains on  [gi|1197510567|ref|YP_009364621|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Hypophthalmichthys nobilis x Hypophthalmichthys molitrix]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.34e-77

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 227.72  E-value: 3.34e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  81 AWGSRSVAGYVLVYLLGVVLAAGLFWGGWYEGSWVVVDGLKEFSMLRGDVSGVAVMYSFGGAMLVICAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1197510567 161 LTRGLSRGTLRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.34e-77

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 227.72  E-value: 3.34e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  81 AWGSRSVAGYVLVYLLGVVLAAGLFWGGWYEGSWVVVDGLKEFSMLRGDVSGVAVMYSFGGAMLVICAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1197510567 161 LTRGLSRGTLRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-146 3.72e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.81  E-value: 3.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  17 IAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPEAWGSRSVAGYVLVYLL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1197510567  97 GVVLAAGLFWGGWYEGSWVVVDGLKEFSMlrgDVSGVAVMYSFGGAMLVI 146
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNI---EAIGELLFTDYLLPFELA 127
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-173 3.34e-77

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 227.72  E-value: 3.34e-77
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00138    1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  81 AWGSRSVAGYVLVYLLGVVLAAGLFWGGWYEGSWVVVDGLKEFSMLRGDVSGVAVMYSFGGAMLVICAWVLLLTLLVVLE 160
Cdd:MTH00138   81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVLRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLE 160

                         170
                  ....*....|...
gi 1197510567 161 LTRGLSRGTLRAV 173
Cdd:MTH00138  161 LTRGLSRGALRAV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-173 8.66e-48

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 153.08  E-value: 8.66e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00065    1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  81 AWGSRSVaGYVLVYLLGVVLAAGLFWGGWYEGSWVVVDGLKEFSMLRGDVSGVAVMYSFGGAMLVICAWVLLLTLLVVLE 160
Cdd:MTH00065   81 AWGSWSV-LVYVLFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLE 159

                         170
                  ....*....|...
gi 1197510567 161 LTRGLSRGTLRAV 173
Cdd:MTH00065  160 VTRGLSRGSLRAV 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-173 2.09e-38

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 129.10  E-value: 2.09e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00115    1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  81 AWGSRSVAGYVLVYLLGVVLAAGLFWGGW-YEGSWVVVDGLKEFSMLRGDVSGVAVMYSFGGAMLVICAWVLLLTLLVVL 159
Cdd:MTH00115   81 AWGDWGVVGYVVGFVLVVVVVGVVVGGLWgMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                         170
                  ....*....|....
gi 1197510567 160 ELTRGLSRGTLRAV 173
Cdd:MTH00115  161 ELVRGLSRGALRAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-149 8.97e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 107.20  E-value: 8.97e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00109    2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1197510567  81 AWGSRSVAGYVLVYLLGVVLAAGLFWGGWYE----------GSWVVVDGlKEFSMLRGDVSGVAVMYSFGGAMLVICAW 149
Cdd:MTH00109   82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEvevvfnfnglGDWVIYDT-GGSGFFSEDAMGVAALYSYGTWLVVVTGW 159
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-173 4.41e-27

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 100.06  E-value: 4.41e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPE 80
Cdd:MTH00214    1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  81 AWGSRSVAGYVLVYLLGVVLAAGLFWGGWYEGSWVVVDGLKEFSMlrgdvSGVAVMYSFGGAMLVICAWVLLLTLLVVLE 160
Cdd:MTH00214   81 SWGGWSVLLFFLFYLLGLGFVGFYFYGGWEMLSWMGVDEANNLDL-----SGVSDLYSRGFFLLLLGGVVLFLVLFVVLE 155

                         170
                  ....*....|...
gi 1197510567 161 LTRGLSRGTLRAV 173
Cdd:MTH00214  156 LVRGLSRGALRVV 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 25-79 7.15e-14

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 65.31  E-value: 7.15e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1197510567  25 PYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFP 79
Cdd:MTH00045   23 PYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP 77
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-146 3.72e-08

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 49.81  E-value: 3.72e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1197510567  17 IAVASNPTPYFAALGLVVAAGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPFPEAWGSRSVAGYVLVYLL 96
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1197510567  97 GVVLAAGLFWGGWYEGSWVVVDGLKEFSMlrgDVSGVAVMYSFGGAMLVI 146
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNI---EAIGELLFTDYLLPFELA 127
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-74 4.69e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 38.71  E-value: 4.69e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1197510567   1 MTYFMFLLLVALVVGLIAVASNPTPYFAALGLVVaaGVGCGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00152    1 MSLMILLSVCFSLFLLLPLSKQPLSLGLVLLLLS--LFVCVEIGLTLSSWYGYLLFLVYVGGLLVMFAYVVSLS 72
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 49-74 7.75e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.17  E-value: 7.75e-03
                          10        20
                  ....*....|....*....|....*.
gi 1197510567  49 SFLSLVLFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00166   46 FWFSYILFLIFLGGMLVLFIYITSLA 71
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 40-74 9.82e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 34.98  E-value: 9.82e-03
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1197510567  40 CGILVGYGGSFLSLVLFLIYLGGMLVVFAYSAALA 74
Cdd:MTH00212   38 CLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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