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Conserved domains on  [gi|168487818|ref|YP_514794|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Sepia officinalis]

Protein Classification

H(+)-translocating NADH:ubiquinone reductase subunit 2( domain architecture ID 11475920)

H(+)-translocating NADH:ubiquinone reductase subunit 2, a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-300 6.93e-71

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 222.07  E-value: 6.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   4 KFFPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNY 83
Cdd:MTH00144   1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  84 SLSWHSMfnsnlsILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSN---LNTIIVISLLS 160
Cdd:MTH00144  81 SFSWFSM------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLywlAYLLCVISVLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 161 AVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPLLNLLSTQTSNYLYSLTHKNK--INNL 238
Cdd:MTH00144 155 ALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPsyKTGL 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 168487818 239 IIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIKS 300
Cdd:MTH00144 235 SIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSS 296
 
Name Accession Description Interval E-value
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-300 6.93e-71

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 222.07  E-value: 6.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   4 KFFPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNY 83
Cdd:MTH00144   1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  84 SLSWHSMfnsnlsILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSN---LNTIIVISLLS 160
Cdd:MTH00144  81 SFSWFSM------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLywlAYLLCVISVLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 161 AVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPLLNLLSTQTSNYLYSLTHKNK--INNL 238
Cdd:MTH00144 155 ALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPsyKTGL 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 168487818 239 IIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIKS 300
Cdd:MTH00144 235 SIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSS 296
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-290 9.55e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 85.94  E-value: 9.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLELN------LMGFLplmniKGKMLEAEASMKYFIIQSLGSSVLI--ISSLIMY 81
Cdd:COG1007  105 YALLLFATLGMMLMASANDLLTLFLGLELLslslyvLVAFR-----RDDRRSSEAALKYFLLGALSSGFLLygISLLYGA 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  82 NYSLSWHSMFNSNLSILLILSLIL------------KLGGAPMHFWLPN---------------LTKQMTWLILFLILTw 134
Cdd:COG1007  180 TGSLNLAGIAAALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDvyegaptpvtaflatAPKIAAFAALLRLLV- 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 135 qklapLFMIMLINSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSL----TFLYFIVYIII 210
Cdd:COG1007  259 -----EAFPGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFM 333

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 211 SIP---LLNLLSTQTS-----NYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIAS 282
Cdd:COG1007  334 NLGafaVILLLSRKGGeaeeiEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNS 413


                 ....*...
gi 168487818 283 LISLYFYL 290
Cdd:COG1007  414 VISAYYYL 421
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 26-282 1.88e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 83.52  E-value: 1.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   26 SSHWLTMWMGLELNLMGFLPLMNIKGKMLEA-EASMKYFIIQSLGSSVLIISSLIMYNYSLSWH-------------SMF 91
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRSsEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSfdelskaltgglnSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   92 NSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLI-LFLILTWQKLAPLFMIMLI-------NSNLNTIIVISLLSAVF 163
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVsALLAATLVKAGGYGLIRRSllylpssPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  164 GSISMLNQTNMQLIITYSSISHLGWMLSMIMLNS----SLTFLYFIVYIIISIPL--------LNLLSTQTSNYLYSLTH 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTiygiQAAIFHLLTHGLFSAGLflcagsviYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 168487818  232 KNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIAS 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 10-290 4.18e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.98  E-value: 4.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   10 FLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNI-KGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSLSWH 88
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLkRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   89 --------------SMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLI-------- 146
Cdd:TIGR01770 185 fedlllflsngmlnISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLflyilfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  147 -NSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSL----TFLYFIVYIIISIPLLNLLS-- 219
Cdd:TIGR01770 265 sEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSll 344

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818  220 -------TQTSNYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL 290
Cdd:TIGR01770 345 rsykdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYL 422
 
Name Accession Description Interval E-value
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 4-300 6.93e-71

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 222.07  E-value: 6.93e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   4 KFFPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNY 83
Cdd:MTH00144   1 MSSPSNLLFLFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  84 SLSWHSMfnsnlsILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSN---LNTIIVISLLS 160
Cdd:MTH00144  81 SFSWFSM------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLywlAYLLCVISVLS 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 161 AVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPLLNLLSTQTSNYLYSLTHKNK--INNL 238
Cdd:MTH00144 155 ALVGSIGGLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSLKPsyKTGL 234

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 168487818 239 IIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIKS 300
Cdd:MTH00144 235 SIISLLLSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSS 296
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 5-300 3.02e-53

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 176.94  E-value: 3.02e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   5 FFPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYS 84
Cdd:MTH00160   3 MNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLNL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  85 lswhSMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNlNTIIVISLLSAVFG 164
Cdd:MTH00160  83 ----MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYLINN-NFIIIIIILSAIIG 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 165 SISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIIS---IPLLNLLSTQTSNYLYSLTHKNKINNLIIP 241
Cdd:MTH00160 158 AIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISlsiILLFNKFNIFFLNQLFNSNNKSKKIKFLLF 237

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 168487818 242 SLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIKS 300
Cdd:MTH00160 238 LNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLN 296
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 8-298 3.93e-48

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 163.84  E-value: 3.93e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   8 SNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSLSW 87
Cdd:MTH00112   5 AKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWNTGQW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  88 --HSMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNTII--VISLLSAVF 163
Cdd:MTH00112  85 diTQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLllTLAILSTLI 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 164 GSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIP---LLNLLSTQTSNYLYSLTHKNKINNLII 240
Cdd:MTH00112 165 GGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPmflTLNTTSTKTLKDMMTSWTKSPTLNTTL 244

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818 241 PSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTII 298
Cdd:MTH00112 245 MLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTI 302
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 7-293 7.36e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 158.09  E-value: 7.36e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   7 PSNFLFILI-MIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSL 85
Cdd:MTH00105   3 PLILIIIYLtLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMYSG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  86 SW--HSMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINS--NLNTIIVISLLSA 161
Cdd:MTH00105  83 QWtiTKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPsiNPNLLLTLAILSI 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 162 VFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIP---LLNLLSTQTSNYLYSLTHKNKINNL 238
Cdd:MTH00105 163 LIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTmfmLLMLNSSTTTLSLSHTWNKTPLMTS 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 168487818 239 IIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMT 293
Cdd:MTH00105 243 LILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLI 297
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 11-294 1.08e-42

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 149.57  E-value: 1.08e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  11 LFILIMIMGTLTTL--SSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSLSW- 87
Cdd:MTH00135   6 LTILLFSLGLGTTLtfASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWLTGQWd 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  88 -HSMFNSNLSILLILSLILKLGGAPMHFWLP------NLTkqmTWLILfliLTWQKLAPLFMIMLI-NSNLNTIIVISLL 159
Cdd:MTH00135  86 iQQMSHPLPTTMITLALALKIGLAPLHFWLPevlqglDLT---TGLIL---STWQKLAPFALILQIaPTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 160 SAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIP---LLNLLSTQTSNYLYSLTHKNKIN 236
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSaflTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 168487818 237 NLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL----SMTL 294
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLrlsyAMTL 301
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 10-290 2.50e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 146.23  E-value: 2.50e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLI--MYNYSLSW 87
Cdd:MTH00041   7 IFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIqaWLSGSWSI 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  88 HSMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNT--IIVISLLSAVFGS 165
Cdd:MTH00041  87 NGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSniLILCGILSVLVGG 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 166 ISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPL---LNLLSTQTSNYLYSLTHKNKINNLIIPS 242
Cdd:MTH00041 167 WGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIfliGNNFSLSTLSHLNKLSQLNPISAFLFIL 246

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 168487818 243 LILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL 290
Cdd:MTH00041 247 SILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYL 294
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 11-298 1.94e-40

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 143.96  E-value: 1.94e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  11 LFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSLSW--H 88
Cdd:MTH00200   8 LFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWTSGQWgiS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  89 SMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNT--IIVISLLSAVFGSI 166
Cdd:MTH00200  88 EMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSniLLLLGLLSVLVGGW 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 167 SMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIP---LLNLLSTQTSNYLYSLTHKNKINNLIIPSL 243
Cdd:MTH00200 168 GGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTvflLLNLLNSTKINSLSSSKTKNPILSMLLGLT 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 168487818 244 ILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTII 298
Cdd:MTH00200 248 LLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLL 302
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 6-300 2.97e-40

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 143.00  E-value: 2.97e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   6 FPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYnysl 85
Cdd:MTH00011   5 FPTMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMW---- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  86 SWHSMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINS--NLNTIIVISLLSAVF 163
Cdd:MTH00011  81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTShnILPMMTSMAAMSALA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 164 GSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPL---LNLLSTQTSNYLYSLTHKNKINNLII 240
Cdd:MTH00011 161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLmllFAYLNAFSTKFNSKISSMSQTTSMSL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 241 PSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIKS 300
Cdd:MTH00011 241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNFMYLS 300
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 18-297 3.39e-39

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 140.44  E-value: 3.39e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  18 MGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSLSWH--SMFNSNL 95
Cdd:MTH00070  15 LGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWFTGEWTimNMQTPLP 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  96 SILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNT--IIVISLLSAVFGSISMLNQTN 173
Cdd:MTH00070  95 TIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSnlLIIMGLLSTLIGGWGGLNQTQ 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 174 MQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPL---LNLLSTQTSNYLYSLTHKNKINNLIIPSLILSLAGM 250
Cdd:MTH00070 175 LRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMflmLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGL 254

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 168487818 251 PPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTI 297
Cdd:MTH00070 255 PPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMS 301
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 10-300 5.78e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 134.03  E-value: 5.78e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNyslswHS 89
Cdd:MTH00197   1 FLFLFIIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFS-----NL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  90 MFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNTIIVISLLSAVFGSISML 169
Cdd:MTH00197  76 YLSLLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMGLLICSVLSSLIGGIGGM 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 170 NQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYIIISIPLLNLLS---TQTSNYLYSLTHKNKINNLIIPSLILS 246
Cdd:MTH00197 156 NQSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSknnLSSLNQQYSNPESMSSNLVFLGLSFLS 235

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 168487818 247 LAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIKS 300
Cdd:MTH00197 236 LGGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILS 289
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
10-290 1.66e-19

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 87.95  E-value: 1.66e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLEL-NLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNY--SLS 86
Cdd:PRK05777 106 YLLVLFALLGMMVMVSANDLLTLFLGLELlSLPLYALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGAtgSLS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  87 WHSMFNSNLSILLILSLIL------------KLGGAPMHFWLPNL-TKQMTWLILFlILTWQKLAPLFMIM--------- 144
Cdd:PRK05777 186 FAGIAKALADGSGNSLLLLfglvfllvglafKLSAVPFHMWTPDVyEGAPTPVTAF-LATAPKIAAFAVLLrllvvafgg 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 145 LINSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSL----TFLYFIVYIIISIPL---LNL 217
Cdd:PRK05777 265 LSEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEgysaVLFYLLAYLFMTLGAfgvISL 344

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818 218 LSTQT--SNYLYSLTHKNKINNL---IIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL 290
Cdd:PRK05777 345 LRRKGgeAESISDFAGLSKRSPLlaaVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYL 422
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 17-290 5.20e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 85.85  E-value: 5.20e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  17 IMGTLTTLSSSHWLTMWMGLELNLMGFLPLM-NIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMY-------------- 81
Cdd:MTH00196   3 ALGILCLISSSNWLSVYLAIELQTLSLFILIaQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCgttgglhlsyinlv 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  82 -NYSLSWHSMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNTIIVISLLS 160
Cdd:MTH00196  83 lNSGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGLNVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 161 AVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNS----SLTFLYFIVYIIISIPLLNLLSTQTSNY-----LYSLTH 231
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSfesiQASLVYLFIYIIMSICVFSIILALNVYKnliieFSGLSR 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 168487818 232 KNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL 290
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYV 301
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 6-289 6.56e-19

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 86.22  E-value: 6.56e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   6 FPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKML-EAEASMKYFIIQSLGSSVLIISSLIMYNYS 84
Cdd:MTH00199  96 GQSSPILILIVALGSLLLVSSINWLSIYLAIELQTLTLFILVALKRDSAySTEAGLKYFVLGAVSSGLFLFGCALLYGLT 175

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  85 --LSWHSMFNSNLS----ILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLNTIIVISL 158
Cdd:MTH00199 176 geTSIQGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPVTNVVLICAV 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 159 LSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNS----SLTFLYFIVYIIISIPLLNLLSTQTSNY-----LYSL 229
Cdd:MTH00199 256 LSIIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSfesiQASLIYMIIYVIMSICSFSIILSLKLTKgliveVSGL 335

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 230 THKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFY 289
Cdd:MTH00199 336 SRKNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYY 395
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 10-290 9.55e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 85.94  E-value: 9.55e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLELN------LMGFLplmniKGKMLEAEASMKYFIIQSLGSSVLI--ISSLIMY 81
Cdd:COG1007  105 YALLLFATLGMMLMASANDLLTLFLGLELLslslyvLVAFR-----RDDRRSSEAALKYFLLGALSSGFLLygISLLYGA 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  82 NYSLSWHSMFNSNLSILLILSLIL------------KLGGAPMHFWLPN---------------LTKQMTWLILFLILTw 134
Cdd:COG1007  180 TGSLNLAGIAAALAAGGANSPLLLlglvlvlaglafKLSAVPFHMWTPDvyegaptpvtaflatAPKIAAFAALLRLLV- 258

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 135 qklapLFMIMLINSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSL----TFLYFIVYIII 210
Cdd:COG1007  259 -----EAFPGLAADWQLLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLLGLAAGTPLgvsaALFYLLAYLFM 333

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 211 SIP---LLNLLSTQTS-----NYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIAS 282
Cdd:COG1007  334 NLGafaVILLLSRKGGeaeeiEDLAGLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNS 413


                 ....*...
gi 168487818 283 LISLYFYL 290
Cdd:COG1007  414 VISAYYYL 421
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 26-282 1.88e-18

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 83.52  E-value: 1.88e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   26 SSHWLTMWMGLELNLMGFLPLMNIKGKMLEA-EASMKYFIIQSLGSSVLIISSLIMYNYSLSWH-------------SMF 91
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGYWGKSPRSsEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSfdelskaltgglnSSG 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   92 NSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLI-LFLILTWQKLAPLFMIMLI-------NSNLNTIIVISLLSAVF 163
Cdd:pfam00361  81 LLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVsALLAATLVKAGGYGLIRRSllylpssPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  164 GSISMLNQTNMQLIITYSSISHLGWMLSMIMLNS----SLTFLYFIVYIIISIPL--------LNLLSTQTSNYLYSLTH 231
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGAGTiygiQAAIFHLLTHGLFSAGLflcagsviYRRVHTRNIRDYGGLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 168487818  232 KNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIAS 282
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 10-290 4.18e-15

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 74.98  E-value: 4.18e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   10 FLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNI-KGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNYSLSWH 88
Cdd:TIGR01770 105 YILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGLkRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLN 184

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   89 --------------SMFNSNLSILLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLI-------- 146
Cdd:TIGR01770 185 fedlllflsngmlnISLLLLGIVLILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLflyilfgf 264

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  147 -NSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSL----TFLYFIVYIIISIPLLNLLS-- 219
Cdd:TIGR01770 265 sEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEgikaVLFYIFIYALMSLGAFGVLSll 344

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818  220 -------TQTSNYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL 290
Cdd:TIGR01770 345 rsykdewIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYL 422
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 10-287 4.13e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 72.10  E-value: 4.13e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNY--SLSW 87
Cdd:COG0651  110 YPLFLLLLAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGAtgTLNM 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  88 HSMFNSNLSILLILSLI----------LKLGGAPMHFWLPN----------------LTKQMTWLILFLILTWQKLAPLF 141
Cdd:COG0651  190 ADLAARLAELDPGLLLAafalllvgfgIKAALFPLHFWLPDaypaapspvsallsglLTKVGVYAILRVLTLLFGADPAL 269

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 142 MIMLInsnlntIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYII---ISIPLLNLL 218
Cdd:COG0651  270 FLGTL------LLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLLnhaLAKALLFLA 343

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 168487818 219 S--------TQTSNYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLY 287
Cdd:COG0651  344 AgaieratgTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLA 420
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 150-290 4.86e-10

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 59.98  E-value: 4.86e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 150 LNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYII---ISIPLLNLLS------- 219
Cdd:PRK12667 295 SPILIILGAVSAIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIInhaIAKSLLFLASgvfihaa 374

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 168487818 220 -TQTSNYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYL 290
Cdd:PRK12667 375 gTRDIDELAGLGRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYF 446
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 2-290 4.88e-09

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 57.18  E-value: 4.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818   2 NNKFFPSNFLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLM---NIKGKMLEA------EASMKYFIIQSLGSSV 72
Cdd:MTH00198 183 NERGPRSGFALVLIVGLGGLLLIESANWLTIYLALEFQTLALFILAgegSQPGSHFPSpgntppESGLKYWILGAMSSGF 262

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  73 LIISSLIMYNYSLSWHSMFNSNLSIL----------------LILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTWQK 136
Cdd:MTH00198 263 YLFGCALYFGFTGNEGMLGTILSATLettnielrqgslgylfITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPK 342

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 137 LAPLFMIMLINSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIM------LNSSLTflYFIVYIII 210
Cdd:MTH00198 343 FTVYILLTSLVITSKLLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSagtyesLQASWT--YAVTYLVS 420

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 211 SIPLLNLLST----------------QTSNY-----LYSLTHKNKINNLIIPSL---ILSLAGMPPLLGFLSKLLMLISL 266
Cdd:MTH00198 421 ALASFTVICTleefgtrtptsrqrdgSFGNYnlvrrLVDLTILSRGQPYIAFSLaivFLSLAGIPPLLGFLGKWFILVGS 500

                        330       340       350
                 ....*....|....*....|....*....|.
gi 168487818 267 MKMNF-------IILTLFMFIASLISLYFYL 290
Cdd:MTH00198 501 IKIAFssslsiyYLVALFAIICTCISAFYYI 531
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 11-285 1.36e-07

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 52.69  E-value: 1.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  11 LFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLpLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMYNY--SLSWH 88
Cdd:PRK08668 102 MFALMSLAGVLGVFLANDLLTLYIFWEIMTFSSF-MMVPMGKKESRKASLKYFVLSAIGAYAMLYAIFLIYAKtgTFDFA 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  89 SM-----------FNSNLSILLILSLILKLGGAPMHFWLPN----------------LTKQMTW---LILFLILTWQKLA 138
Cdd:PRK08668 181 DIsqglindtstgFALIVFLFLLAFGVAKAGIFPLHVWAPDayseapqsfsavlsgqLSKLGAYgflLVLYVLPGTKLFS 260

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 139 PLFMIMLINSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTF---LYFIVYIIISIPLL 215
Cdd:PRK08668 261 EFGTYRGVPLFNYILAWLGNISIIVGTLMAILQEDIKKLIAYSSVANGGYILVGLGLGTSLGFaggLFHVFNHALFKGLF 340

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818 216 NL------LSTQTSNY--LYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLIS 285
Cdd:PRK08668 341 FLifaaviYRTGTTKIseMGGLIEKMPFTFAMYLVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGS 418
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
155-299 2.18e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 51.98  E-value: 2.18e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 155 VISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMlsMIMLNS------SLTFLYFIVYIIIS------IPLLNLL--ST 220
Cdd:PRK02504 281 ALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFV--MIGLVAgteagyASMVFYLLAYLFMNlgafacVILFSLRtgTD 358

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 168487818 221 QTSNYlYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIK 299
Cdd:PRK02504 359 QISDY-AGLYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVIKMMVVK 436
ndhB CHL00049
NADH dehydrogenase subunit 2
 155-299 1.88e-06

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 48.85  E-value: 1.88e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 155 VISLLSAVFGSISMLNQTNMQLIITYSSISHLGW-MLSMIMLNSSLTFLYFIVYIIISIpLLNL----------LSTQTS 223
Cdd:CHL00049 285 ILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYI-FMNLgtfacivlfgLRTGTD 363

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818 224 NYL-YS-LTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLYFYLSMTLMTIIK 299
Cdd:CHL00049 364 NIRdYAgLYTKDPFLALSLALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKIIKLLMTG 441
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 106-286 7.26e-06

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 47.18  E-value: 7.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 106 KLGGAPMHFWLPN----------------LTKQMTWLILFLILTwqklAPLFMIMLINSNLNTIIVISLLSAVFGSISML 169
Cdd:PRK08375 215 KAAVFPLHTWLPRaypaappvvtallsglVTKVAVYALIRIYFT----VFGGDFRFALGLGWLLAVLALLSMLVGSLAAL 290

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 170 NQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYII---ISIPLLNLLS--------TQTSNYLYSLTHKNKINNL 238
Cdd:PRK08375 291 GQDDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLLhhaLMKGALFLAAgaievtygTRRLSELSGLGRRMPLTAA 370

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 168487818 239 IIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISL 286
Cdd:PRK08375 371 AFAVASLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLAL 418
PRK12662 PRK12662
putative monovalent cation/H+ antiporter subunit D; Reviewed
 120-288 3.25e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 183662 [Multi-domain]  Cd Length: 492  Bit Score: 45.11  E-value: 3.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 120 TKQMTWLILFLILTWQKLAPLFMIMLINsnlNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSL 199
Cdd:PRK12662 252 TKVMIYLIIRIVYDVFKANFVFTTLPFN---NVFMILAALAIVFGSVLAILSKDIKRIFAYSSISHIGYIILAVSLNTYY 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 200 TFLYFIVYIII-SIPLLNLLSTQTS-NYLYSLTHKNKINNL--IIPS-------LILSLAGMPPLLGFLSKLLMLISLMK 268
Cdd:PRK12662 329 GLAAAVAYIVNhSIVKSALFMVSGSiSYHFGTTKLEDCLNLwkSMPKitlafvlLSLSLIGMPPTSGFVAKWYILDAFIK 408

                        170       180
                 ....*....|....*....|
gi 168487818 269 MNFIILTLFMFIASLISLYF 288
Cdd:PRK12662 409 SNAWIGLVVLLVGSGLSVIY 428
PRK12650 PRK12650
DUF4040 family protein;
111-267 4.94e-05

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 44.65  E-value: 4.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 111 PMHFWLPNLTKQMTWLILFL---------ILTWQKLAPLFMIMLINSNLntIIVISLLSAVFGSISMLNQTNMQLIITYS 181
Cdd:PRK12650 226 PFHFWLPEAMAAITPVSAFLhaaavvkagIYLLLRFSPVFHDVAVWNWL--LIIVGMITALMGAVFAVQKTDLKKLTAYS 303

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 182 SISHLGWMLSMIMLNSSLTFLYFIVYIIIS-------IPLLNLLSTQTSNY----LYSLTHKNKINNLIIPSLILSLAGM 250
Cdd:PRK12650 304 TVSQLGWIVATIGVGTPFALTAAVVHTLAHalfksslFMLIGVVDHQAGTRdirrLGSLWRRMPFTFVSVTIAALSMAAV 383

                        170
                 ....*....|....*..
gi 168487818 251 PPLLGFLSKLLMLISLM 267
Cdd:PRK12650 384 PPLFGFVSKEGMLTAFL 400
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 39-289 1.23e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 43.16  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  39 NLMGFLPLMNIKGKMLEA---------EASMKYFIIQSLGSSVLIISSLIMY------NYSLSWHSMFNSNLSI------ 97
Cdd:PRK08376 145 NFFVFLEIMSIASYALVAfrndtweaiEAGIKYMFVGSLASSMVLLGIALLYgqygtlNMAYLAVKMSENPTVVakiala 224

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  98 LLILSLILKLGGAPMHFWLPNLTKQMTWLILFLILTwQKLAPLFMIMLIN-------SNLNT----IIVISLLSAVFGSI 166
Cdd:PRK08376 225 LFIAGLAMKSGAVPVHMWLPDAYPAAPSSISAMLLV-IKQAGLYALARVLfsiygpaINLATvgwvIIILGCLTMFVGVA 303

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 167 SMLNQTNMQLIITYSSISHLGWML-----SMIMLNSSLTF----------LYFIVYIIISIPLLNL--------LSTQTS 223
Cdd:PRK08376 304 MAVVQKDVKRLLAYHSVSQIGYMLlglgvGLAALGDPAMAsygeialaggIYHIVNHALYKALLFLtagaviyeTGTRNL 383

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 168487818 224 NYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNfIILTLFMFIASLISLYFY 289
Cdd:PRK08376 384 NELGGLARTMPKTTIAFLIGAAAIVGLPPFNGFASKWLIYESSALFN-PILGVIAMIGSVLTLASF 448
PRK07691 PRK07691
putative monovalent cation/H+ antiporter subunit D; Reviewed
 151-287 2.32e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 181085 [Multi-domain]  Cd Length: 496  Bit Score: 42.63  E-value: 2.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 151 NTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYII--ISIPLLNLLSTQTSNYLYS 228
Cdd:PRK07691 276 YLILILALLTIIFGVIGAVAYFDIKKIIIYNIMIAVGVILVGVAMMTESGMIGAIYYLIhdMIVKAALFLLIGIMIKITG 355

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 168487818 229 LTHKNKINNLI--IPSL-------ILSLAGMPPLLGFLSKLLMLISLMKMNFIILTLFMFIASLISLY 287
Cdd:PRK07691 356 TTDLKKMGGLIkrYPVLgwmffiaALSLAGIPPLSGFYGKFFIVEGTFEAGFYVSGIIVLLSSLLVLY 423
PRK12647 PRK12647
putative monovalent cation/H+ antiporter subunit A; Reviewed
 107-282 1.06e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237156 [Multi-domain]  Cd Length: 761  Bit Score: 40.67  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 107 LGGA-------PMHFWLPNLTKQMTWLILFLILTWQKLAPLFMIMLINSNLN-------TIIVISLLSAVFGSISMLNQT 172
Cdd:PRK12647 202 LGGAftksaqfPFHFWLPNAMEAPTPVSAYLHSATMVKAGIYLLARLNPVLGgtplwqtILPLFGGLTMLTGALLAVRQT 281

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 173 NMQLIITYSSISHLGWMLSMIMLNSSLTFLYFIVYII-----------ISIPLLNLLSTQTSNYLYSLTHKNKINNLIIP 241
Cdd:PRK12647 282 DLKLILAYSTVSALGTLVMLLGLGSELAIKAAVLFLVahslykgalfmVAGIIDHETGTRDITKLGGLRRAMPITAAAAL 361

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 168487818 242 SLILSLAGMPPLLGFLSKLLMLISLMKMNF--IILTLFMFIAS 282
Cdd:PRK12647 362 LAALSMAGLPPLFGFLAKELIYEALLEAPLwsLILTVAAVLGN 404
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 10-286 2.54e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 39.14  E-value: 2.54e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  10 FLFILIMIMGTLTTLSSSHWLTMWMGLELNLMGFLPLMNIKGKMLEAEASMKYFIIQSLGSSVLIISSLIMY-------- 81
Cdd:PRK06458 111 YGMYQLFLFTMLLALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIICSVGVAFALFGTILVYanaatvmg 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  82 --NYSLSWHSMFNSNLSILLILSLI----------LKLGGAPMHFWLPN-----------------LTKQMTWLILFLIL 132
Cdd:PRK06458 191 dgEMAILWTELLKHASLLDPTLMKLafvflligfgTKVGLFPMHAWLPDahseapspvsallsgvlLNVALYAVLRYYIL 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 133 TWQKLAPLFMIMLinsnlntIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMI--------------MLNSS 198
Cdd:PRK06458 271 IDAAIGSDFPGRL-------LLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIAFALgiggplgifaallhMLNHS 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 199 LT--FLYFIVYIIISIpllnlLSTQTSNYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMNFIILTL 276
Cdd:PRK06458 344 LTksAIFFASGNVLQK-----YGTRDINVIRGLLKVSPLTGWGLMLGALAIAGMPPFGVFISEFLILTAGLARGPLLIAI 418

                        330
                 ....*....|
gi 168487818 277 FMFIASLISL 286
Cdd:PRK06458 419 LLLLLLTLAF 428
PRK12646 PRK12646
DUF4040 family protein;
63-292 2.82e-03

DUF4040 family protein;


Pssm-ID: 183646 [Multi-domain]  Cd Length: 800  Bit Score: 39.35  E-value: 2.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818  63 FIIQSLGSSVLIISSLIMYNYSLSWHSMFNSNLSILLILSLIlKLGGAPMHFWLPNLTKQMTWLILFLILTWQKLAPLFM 142
Cdd:PRK12646 181 FIMLYIMTGTNNITEILGQADHIKNHGLFIPMIFMFLLGAFT-KSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFL 259

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 143 IM-------LINSNLNTIIVISLLSAVFGSISMLNQTNMQLIITYSSISHLGWMLSMIMLNSSLTF-----LYFIVYIII 210
Cdd:PRK12646 260 LFrftpllgLSNMYIYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQhqqdaIASIYVFVL 339

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 168487818 211 SIPLLNLLS--------------------TQTSNYLYSLTHKNKINNLIIPSLILSLAGMPPLLGFLSKLLMLISLMKMN 270
Cdd:PRK12646 340 FAALFHLMNhaifkcalfmgvgiidheagTRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTG 419

                        250       260       270
                 ....*....|....*....|....*....|.
gi 168487818 271 ---------FIILTLFMFIASLISLYFYLSM 292
Cdd:PRK12646 420 qlsqfslisMIIIVFIGVIASIFTFTYALYM 450
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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