2HAI: Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor

PDB ID: 2HAIDownload
MMDB ID: 41014
PDB Deposition Date: 2006/6/12
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 1.58  Å
Source Organism:
Similar Structures:
Biological Unit for 2HAI: monomeric; determined by author
Molecular Components in 2HAI
Label Count Molecule
Protein (1 molecule)
1
Hepatitis C Virus Ns5b RNA Polymerase
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE(6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303