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The Sequence Read Archive (SRA) stores raw sequence data from "next-generation" sequencing technologies including Illumina, 454, IonTorrent, Complete Genomics, PacBio and OxfordNanopores. In addition to raw sequence data, SRA now stores alignment information in the form of read placements on a reference sequence.

SRA is NIH’s primary archive of high-throughput sequencing data and is part of the international partnership of archives (INSDC) at the NCBI, the European Bioinformatics Institute and the DNA Database of Japan. Data submitted to any of the three organizations are shared among them.

Please check SRA Overview for more information.

Submitting to SRA

Making data available to the research community enhances reproducibility and allows for new discovery by comparing data sets.

Using SRA Data with SRA Toolkit

Use SRA data to validate experimental results, increase sample sizes, determine variance and open up new avenues of research.