BioProject

Cystic echinococcosis (CE) is a zoonotic infection caused by larval (metasestod) stages of sestodes belonging to the genus Echinococcus and the Taeniidae family. More...

Cystic echinococcosis (CE) is a zoonotic infection caused by larval (metasestod) stages of sestodes belonging to the genus Echinococcus and the Taeniidae family. CE, Turkey, Mediterranean countries, Middle East, South America, New Zealand and South Africa are endemic. Molecular analysis has shown that E. granulosus can be divided into 10 genotypes, which correspond to the strain definition. E. granulosus produces a lipoprotein known as Echinococcus granulosus Antigen B (EgAgB). EgAgB has been reported as an immunoregulatory molecule that elicits both cellular and humoral immune responses in intermediate hosts and takes part in some of the host-parasite interactions responsible for parasite survival in hydatid cyst. In this study; The EgAgB polymorphism study is aimed to be performed in KE materials to be obtained from intermediate hosts using molecular techniques. In this way, it is aimed to contribute to the implementation of effective control programs against CE disease by regional and country basis by revealing the genotype-antigenic polymorphism relationship in our region. Less...