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Accession: PRJNA1169324 ID: 1169324

The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation (house mouse)

See Genome Information for Mus musculus

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70852 additional projects are related by organism.

Defective glucose-stimulated insulin secretion (GSIS) and β-cell senescence are hallmarks in diabetes. More...

Accession	PRJNA1169324; GEO: GSE278865
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Submission	Registration date: 5-Oct-2024 Department of Endocrinology and Metabolism, Zhongshan Hospital, Fudan University
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	6
Other datasets
BioSample	6
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	5

SRA Data Details

Parameter	Value
Data volume, Gbases	40
Data volume, Mbytes	16324

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The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senesc...
The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation
The mitochondrial enzyme pyruvate carboxylase restricts pancreatic β-cell senescence by blocking p53 activation

BioProject
Matrix Selection for the Visualization of Small Molecules and Lipids in Brain Tu...
Matrix Selection for the Visualization of Small Molecules and Lipids in Brain Tumors Using Untargeted MALDI-TOF Mass Spectrometry Imaging
Matrix Selection for the Visualization of Small Molecules and Lipids in Brain Tumors Using Untargeted MALDI-TOF Mass Spectrometry Imaging

BioProject
Gene expression profile at single cell level of lung alveolar macrophages (AM) a...
Gene expression profile at single cell level of lung alveolar macrophages (AM) and interstital macrophages (IM) in MMTV-HER2 and wildtype early stage (16-week) or late stage (32-week) mice.
Gene expression profile at single cell level of lung alveolar macrophages (AM) and interstital macrophages (IM) in MMTV-HER2 and wildtype early stage (16-week) or late stage (32-week) mice.

BioProject
Armillaria sp. BSP X strain X140.9 actin-1 gene, partial cds
Armillaria sp. BSP X strain X140.9 actin-1 gene, partial cds
gi|222542973|gb|FJ618635.1|

Nucleotide
Ectoparasitic Infestations
Ectoparasitic Infestations
Infestations by PARASITES which live on, or burrow into, the surface of their host's EPIDERMIS. Most ectoparasites are ARTHROPODS.<br/>Year introduced: 1968

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