See
Genome Information for Mus musculus
Bulk RNAseq of Cftr+/+ and Cftr-/- Th2 cells. Using next generation transcriptomics and pathway enriched mechanistic studies, we report that CFTR decreases sensitivity of CD4+ T cells to IL-4, thereby reducing GATA3 expression.
| Accession | PRJNA1169855 |
| Data Type | Raw sequence reads |
| Scope | Multiisolate |
| Organism | Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus |
| Grants | - "Inhibiting CD4+ Th2 development and function by CFTR activity" (Grant ID K08 AI181763, National Institute of Allergy and Infectious Diseases Extramural Activities)
- "Inhibiting CD4+ Th2 development and function by CFTR activity." (Grant ID K08 AI181763, National Institute of Allergy and Infectious Diseases Extramural Activities)
- "Inhibiting CD4+ Th2 development and function by CFTR activity" (Grant ID COOK24A0-KB, Cystic Fibrosis Foundation)
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| Submission | Registration date: 7-Oct-2024
University of Iowa |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
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| Sequence data |
| SRA Experiments | 6 |
| Other datasets |
| BioSample | 6 |