For the development of human cellular models of microglial that allow for exploring disease underlying mechanisms and testing potential therapeutic compounds on a larger scale we generated microglia-like cells from human induced pluripotent stem cells (iPSC) and performed subsequent phenotypic and functional testing and validation by using bulk RNASeq.
| Accession | PRJNA667596 |
| Data Type | Raw sequence reads |
| Scope | Multispecies |
| Publications | Reich M et al., "Alzheimer's Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia.", Front Immunol, 2020;11:617860 |
| Submission | Registration date: 6-Oct-2020
F. Hoffmann - La Roche Ltd |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Sequence data |
| SRA Experiments | 20 |
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| BioSample | 20 |
| GEO DataSets | 1 |