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Accession: PRJNA264171 ID: 264171

Homo sapiens (human)

Preclinical antitumor activity of ST7612AA1: a novel second generation oral histone deacetylase (HDAC) inhibitor

See Genome Information for Homo sapiens
assess the efficacy of ST7612AA1 oral pan-histone deacetylase inhibitor (HDACi), with respect to various solid and haematological tumors, and to characterize its mechanism of action Overall design: GEP analysis of two lymphoma cell lines with and without treatment
AccessionPRJNA264171; GEO: GSE62460
Data TypeTranscriptome or Gene expression
ScopeMultiisolate
OrganismHomo sapiens[Taxonomy ID: 9606]
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens
PublicationsVesci L et al., "Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.", Oncotarget, 2015 Mar 20;6(8):5735-48
SubmissionRegistration date: 17-Oct-2014
Lymphoma & Genomics Research Program, IOR
RelevanceMedical
Project Data:
Resource NameNumber
of Links
Publications
PubMed1
PMC1
Other datasets
GEO DataSets2
GEO Data Details
ParameterValue
Data volume, Spots566772
Data volume, Processed Mbytes14
Data volume, Supplementary Mbytes3

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