SHP2 Blockade Sensitizes Metastatic Triple Negativ... (ID 526210) - BioProject

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Accession: PRJNA526210 ID: 526210

SHP2 Blockade Sensitizes Metastatic Triple Negative Breast Cancer to PI3K Inhibition (house mouse)

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71202 additional projects are related by organism.

Next Generation Sequencing was applied to investigate the effects of PI3K inhibition and/or SHP2 inhibition on the mouse mammary carcinoma 4T1. More...

Accession	PRJNA526210; GEO: GSE128051
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mus musculus[Taxonomy ID: 10090] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus; Mus musculus
Publications	Amante RJ et al., "PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer.", J Mammary Gland Biol Neoplasia, 2023 Jun 9;28(1):13
Submission	Registration date: 8-Mar-2019 THMR, DBM, University Hospital Basel
Relevance	Model Organism

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	18
Publications
PubMed	1
PMC	1
Other datasets
BioSample	18
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	2

SRA Data Details

Parameter	Value
Data volume, Gbases	64
Data volume, Mbytes	25236

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SHP2 Blockade Sensitizes Metastatic Triple Negative Breast Cancer to PI3K Inhibi...
SHP2 Blockade Sensitizes Metastatic Triple Negative Breast Cancer to PI3K Inhibition
SHP2 Blockade Sensitizes Metastatic Triple Negative Breast Cancer to PI3K Inhibition

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rpn10 19S proteasome regulatory subunit Rpn10 [Schizosaccharomyces pombe]
rpn10 19S proteasome regulatory subunit Rpn10 [Schizosaccharomyces pombe]
Gene ID:2543682

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Gene Links for GEO Profiles (Select 46501443) (1)
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ZNF484 zinc finger protein 484 [Homo sapiens]
ZNF484 zinc finger protein 484 [Homo sapiens]
Gene ID:83744

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