See
Genome Information for Homo sapiens
FAT10 interacts with MAD2 and caused tumor progression. The hypothesis tested in the present study was FAT10 induces tumor progression through its binding to MAD2 and Disruption of this binding restored its global gene expression
Overall design: Total RNA obtained from wild-type HCT116, stable FAT overexpressed HCT116, and FAT10 mutants, where its binding with MAD2 was disrupted or abolished.
| Accession | PRJNA235857; GEO: GSE54167 |
| Data Type | Transcriptome or Gene expression |
| Scope | Multiisolate |
| Organism | Homo sapiens[Taxonomy ID: 9606] Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo; Homo sapiens |
| Publications | Theng SS et al., "Disruption of FAT10-MAD2 binding inhibits tumor progression.", Proc Natl Acad Sci U S A, 2014 Dec 9;111(49):E5282-91 |
| Submission | Registration date: 16-Jan-2014
Liver Cancer Functional Genomics, Biochemistry, National University of Singapore |
| Relevance | Medical |
Project Data:
| Resource Name | Number
of Links |
|---|
| Publications |
| PubMed | 1 |
| PMC | 1 |
| Other datasets |
| GEO DataSets | 2 |
GEO Data Details| Parameter | Value |
|---|
| Data volume, Spots | 473230 |
| Data volume, Processed Mbytes | 13 |
| Data volume, Supplementary Mbytes | 3 |