The lack of the TetR-like repressor gene BCG_2177c... (ID 733047) - BioProject

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Accession: PRJNA733047 ID: 733047

The lack of the TetR-like repressor gene BCG_2177c (Rv2160A) may help mycobacteria overcome intracellular redox stress and survive longer inside macrophages when surrounded by a lipid environment

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We analyzed the genes expressed, or the transcriptome, of bacilli Mycobacterium bovis BCG Pasteur (wtBCG) and a mutant strain obtained by transposition of the gene BCG_ BCG_2177c (mtBCG), cultured in the presence of a lipid mixture (fatty acids/cholesterol) as main carbon source. More...

Accession	PRJNA733047; GEO: GSE175579
Data Type	Transcriptome or Gene expression
Scope	Multiisolate
Organism	Mycobacterium tuberculosis variant bovis BCG[Taxonomy ID: 33892] Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex; Mycobacterium tuberculosis; Mycobacterium tuberculosis variant bovis BCG
Publications	García-Morales L et al., "The Lack of the TetR-Like Repressor Gene BCG_2177c (Rv2160A) May Help Mycobacteria Overcome Intracellular Redox Stress and Survive Longer Inside Macrophages When Surrounded by a Lipid Environment.", Front Cell Infect Microbiol, 2022;12:907890
Submission	Registration date: 26-May-2021 MOLECULAR BIOMEDICIN, Center for Research and Advanced Studies of the National Polytechnic Institute
Relevance	Unknown

Project Data:

Resource Name	Number of Links
Sequence data
SRA Experiments	8
Publications
PubMed	1
PMC	1
Other datasets
BioSample	8
GEO DataSets	1

GEO Data Details

Parameter	Value
Data volume, Supplementary Mbytes	1

SRA Data Details

Parameter	Value
Data volume, Gbases	14
Data volume, Mbytes	10151

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The lack of the TetR-like repressor gene BCG_2177c (Rv2160A) may help mycobacteria overcome intracellular redox stress and survive longer inside macrophages when surrounded by a lipid environment

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