BioProject

Streptococcus pyogenes (a.k.a. Group A Streptococcus, GAS) is a genetically diverse human pathogen (having > 220 serotypes/M types as of 6/15/2015) that commonly causes superficial infections of the throat (pharyngitis/strep-throat) and skin (impetigo). More...

Streptococcus pyogenes (a.k.a. Group A Streptococcus, GAS) is a genetically diverse human pathogen (having > 220 serotypes/M types as of 6/15/2015) that commonly causes superficial infections of the throat (pharyngitis/strep-throat) and skin (impetigo). Less commonly GAS also causes fulminant invasive infections, such as necrotizing fasciitis (flesh-eating disease) and necrotizing pneumonia, that have high attendant morbidity and mortality. Serotype M89 strains are a prevalent cause of GAS pharyngeal and invasive infections. The whole genome sequence of strain MGAS23530, a pharyngeal infection isolate, was undertaken to gain insight in the genetic basis of GAS serotype M89 pathogenesis. Less...