Metagenome-assembled genome: ERR321467_bin.95_CONC... - BioSample

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Metagenome-assembled genome: ERR321467_bin.95_CONCOCT_v1.1_MAG

Identifiers: BioSample: SAMEA14084186; SRA: ERS11687319

Organism: uncultured Alistipes sp.
cellular organisms; Bacteria; FCB group; Bacteroidota/Chlorobiota group; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; environmental samples

Attributes

collection date	2008-01-01
broad-scale environmental context	Host-associated
local-scale environmental context	Human
environmental medium	Digestive system
geographic location	Denmark
investigation type	metagenome-assembled genome
isolation source	human gut metagenome
project name	We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we report the human gut microbial composition in a population sample of 123 non-obese and 169 obese Danish individuals. We find two groups of individuals that differ by the number of gut microbial genes and thus gut bacterial richness. They harbour known and previously unknown bacterial species at different proportions; individuals with a low bacterial richness (23% of the population) are characterized by more marked overall adiposity, insulin resistance and dyslipidaemia and a more pronounced inflammatory phenotype when compared with high bacterial richness individuals. The obese individuals among the former also gain more weight over time. Only a few bacterial species are sufficient to distinguish between individuals with high and low bacterial richness, and even between lean and obese. Our classifications based on variation in the gut microbiome identify subsets of individuals in the general white adult population who may be at increased risk of progressing to adiposity-associated co-morbidities.
sample name	ERR321467_bin.95_CONCOCT_v1.1_MAG
ENA-CHECKLIST	ERC000047
ENA-FIRST-PUBLIC	2023-01-03
ENA-LAST-UPDATE	2023-01-03
External Id	SAMEA14084186
INSDC center alias	EBI
INSDC center name	European Bioinformatics Institute
INSDC first public	2023-01-03T00:33:17Z
INSDC last update	2023-01-03T00:33:17Z
INSDC status	public
Submitter Id	ERR321467_bin.95_CONCOCT_v1.1_MAG
assembly quality	Multiple fragments where gaps span repetitive regions. Presence of the 23S, 16S, and 5S rRNA genes and at least 18 tRNAs
assembly software	spades_v3.11.1
binning parameters	Default
binning software	CONCOCT v1.1
broker name	EMG broker account, EMBL-EBI
completeness score	96.9
completeness software	CheckM
contamination score	1.43
geographic location (latitude)	55.676098
geographic location (longitude)	12.568337
metagenomic source	human gut metagenome
sample derived from	SAMEA2163575
scientific_name	uncultured Alistipes sp.
sequencing method	Illumina Genome Analyzer IIx
taxonomic identity marker	multi-marker approach

Description: This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR321467 of study ERP003612.