Table 2.

Select Features of Pseudoxanthoma Elasticum (PXE)

Feature% of Persons
with Feature
Comment
Skin lesions100%In advanced stages, skin can become lax & redundant; sometimes reconstructive surgery is necessary.
Retinal involvement100%Subretinal neovascularization w/hemorrhage can cause significant visual impairment.
Vascular (arterial
arrowing)
60%Can cause claudication, small strokes, intestinal angina, renovascular hypertension, angina &/or myocardial infarction
GI bleeding10%Most commonly in the upper GI tract

GI = gastrointestinal

From: Pseudoxanthoma Elasticum

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