Table 5.

Recommended Surveillance for Individuals with NF2-Related Schwannomatosis

System/ConcernEvaluationFrequency
Neurologic Neurologic exam by provider w/experience in NF2Annually
Brain MRIAnnually beginning at age 10-12 yrs until 4th decade of life 1, 2
Hearing Hearing eval, incl BAER 3Annually
Eyes Complete ophthalmology exam

BAER = brain stem auditory evoked response; NF2 = NF2-related schwannomatosis

1.

Annual brain MRI can start at an older age in individuals from families in which the onset of tumors is known to be later [Evans et al 2005a].

2.

It is not clear if earlier surveillance (e.g., brain MRI before age 10 years) is beneficial, and it is not known at what age surveillance by brain MRI can be safely stopped.

3.

May be useful in detecting changes in auditory nerve function before changes can be visualized by brain MRI.

From: NF2-Related Schwannomatosis

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