Figure 1. [Map of the BWS locus on 11p15.5]. - GeneReviews® - NCBI Bookshelf

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Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024.

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Figure 1. . Map of the BWS locus on 11p15.

Figure 1.

Map of the BWS locus on 11p15.5

a) A schematic representation of the normal parent of origin-specific imprinted allelic expression. Note: b) and c) show the altered region only. The image is not drawn to scale.

Cen = centromere; DMR = differentially methylated region; IC = imprinting center; M = maternal; OT1 = KCNQ1 antisense transcript, KCNQ1OT1; P = paternal; Tel = telomere

Republished with permission from Choufani et al [2010]

From: Beckwith-Wiedemann Syndrome

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Shuman C, Kalish JM, Weksberg R. Beckwith-Wiedemann Syndrome. 2000 Mar 3 [Updated 2023 Sep 21]. In: Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024. Figure 1. [Map of the BWS locus on 11p15.5].
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