Table 6.

Recommended Surveillance for Individuals with Juvenile Polyposis Syndrome

Gastrointestinal Assess for rectal bleeding, anemia, abdominal pain, constipation, diarrhea, or change in stool size, shape, &/or color.At each visit
Complete blood countAs needed based on symptoms
  • Colonoscopy
  • Upper endoscopy
  • Note: Following surgical bowel resection, continue screening for polyps in remaining colon, rectum, & ileal pouch.
  • Every 3 yrs beginning at age 15 yrs or earlier if symptomatic
  • If polyps are found: following polyp treatment, annual screening until no polyps are found, then screening every 3 yrs
  • In those w/o germline SMAD4 or BMPR1A pathogenic variant: every 5 yrs in adulthood if no polyps are found
Hematologic / Cardiovascular Note: To date, frequency of echocardiography monitoring for aortopathy has not been determined. 1

From: Juvenile Polyposis Syndrome

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