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Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024.

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Figure 1. . Four girls who attended the 2005 Costello Syndrome Conference in St Louis show several characteristic features, including the friendly, sociable personality associated with Costello syndrome.

Figure 1.

Four girls who attended the 2005 Costello Syndrome Conference in St Louis show several characteristic features, including the friendly, sociable personality associated with Costello syndrome.

A. The two girls, both age ten years, have full cheeks, full lips, ocular hypertelorism, downslanted eyes, and a full nasal tip. Note that the girl on the left has coarse curly hair, whereas the girl on the right has straight, fine hair.

B. Two girls ages six and nine years show the typical hand posture, wide mouth, and full lips. The darker complexion is attributed to Latino descent in one and African American descent in the other.

From: HRAS-Related Costello Syndrome

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