Table 8.

Recommended Surveillance in Individuals with Familial Hypercholesterolemia

System/ConcernEvaluationComment
Cardiovascular Measurement of lipid levels: TC, LDL-C, HDL-C, triglycerides, lipoprotein(a)
  • In children: Begin at age 2 yrs & monitor closely. At a minimum reassess cholesterol levels between age 9-11 yrs. 1
    Some experts advocate for screening children for ↑ lipoprotein(a), but this practice is not universal. 1, 2
  • In adults: The interval of follow-up testing TBD by care team & based on presence of other risk factors
Consider noninvasive imaging modalities (e.g., measurement of carotid intima-media thickness) to help inform treatment decisions.In children: Currently, the routine use of imaging (e.g., measurement of carotid intima-media thickness) is not recommended.
Identify modifiable risk factors: smoking, sedentary behavior, hypertension, diabetes, & obesity.

HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; TBD = to be determined; TC = total cholesterol

1.
2.

From: Familial Hypercholesterolemia

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