List of abbreviations

SJ Allen; K Wareham; D Wang; C Bradley; B Sewell; H Hutchings; W Harris; A Dhar; H Brown; A Foden; MB Gravenor; D Mack; CJ Phillips

List of abbreviations

AAD: antibiotic-associated diarrhoea
ABMUHB: Abertawe Bro Morgannwg University Health Board
ACE: angiotensin-converting enzyme
CDD: Clostridium difficile diarrhoea
CDDFT: County Durham and Darlington Foundation Trust
CDI: Clostridium difficile infection
CEAC: cost-effectiveness acceptability curve
cfu: colony-forming unit
CI: confidence interval
COPD: chronic obstructive pulmonary disease
CTA: clinical trial authorisation
EQ-5D: European Quality of Life-5 Dimensions
GP: general practitioner
HIV: human immunodeficiency virus
HRQL: health-related quality of life
ICER: incremental cost-effectiveness ratio
IMP: investigational medicinal product
IQR: interquartile range
ISRCTN: International Standard Randomised Controlled Trial Number
ITT: intention to treat
MCS: mental component summary
MedDRA: Medical Dictionary for Regulatory Activities
MHRA: Medicines and Healthcare products Regulatory Agency
NCIMB: National Collection of Industrial, Food and Marine Bacteria
NGT: nasogastric tube
NIHR: National Institute for Health Research
OR: odds ratio
PCS: physical component summary
PLACIDE: probiotic lactobacilli and bifidobacteria in antibiotic-associated diarrhoea and Clostridium difficile diarrhoea in the elderly
PP: per protocol
PPI: proton pump inhibitor
PT: preferred term
QALY: quality-adjusted life-year
QoL: quality of life
RCT: randomised controlled trial
REC: Research Ethics Committee
RR: relative risk
SAE: serious adverse event
SF-12 v2: generic Short Form questionnaire-12 items version 2
SOC: system organ class
VAS: visual analogue scale
WCC: white blood cell count

Publication Details

Copyright

Copyright © Queen’s Printer and Controller of HMSO 2013. This work was produced by Allen et al. under the terms of a commissioning contract issued by the Secretary of State for Health. This issue may be freely reproduced for the purposes of private research and study and extracts (or indeed, the full report) may be included in professional journals provided that suitable acknowledgement is made and the reproduction is not associated with any form of advertising. Applications for commercial reproduction should be addressed to: NIHR Journals Library, National Institute for Health Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK.

Included under terms of UK Non-commercial Government License.

Publisher

NIHR Journals Library, Southampton (UK)

NLM Citation

Allen SJ, Wareham K, Wang D, et al. A high-dose preparation of lactobacilli and bifidobacteria in the prevention of antibiotic-associated and Clostridium difficile diarrhoea in older people admitted to hospital: a multicentre, randomised, double-blind, placebo-controlled, parallel arm trial (PLACIDE). Southampton (UK): NIHR Journals Library; 2013 Dec. (Health Technology Assessment, No. 17.57.) List of abbreviations.