Figure 2. Organization of endodermal progenitors and extraembryonic endoderm at onset of gastrulation in chick and mouse embryos.

Figure 2Organization of endodermal progenitors and extraembryonic endoderm at onset of gastrulation in chick and mouse embryos.

Extraembryonic endoderm lineages and the fate of epiblast cells are color-coded. The territories of prospective endoderm, mesoderm and neurectoderm are separated by sharp boundaries only for the sake of simplification. In the mouse, posterior VE is speculated to be the equivalent of the chick endoblast due to its analogous position. Likewise in the proximal epiblast, prechordal plate progenitor cells are predicted to reside in between definitive endoderm precursors and posterior VE in analogy to chick, even though the limited resolution of current fate maps cannot distinguish two separate populations in the mouse epiblast.

From: Endoderm specification

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StemBook [Internet].
Cambridge (MA): Harvard Stem Cell Institute; 2008-.
Copyright: © 2008 Anne Grapin-Botton.

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