Box 2Non-immediate reactions without systemic involvement

Widespread red macules or papules (exanthem-like)Onset usually 6–10 days after first drug exposure or within 3 days of second exposure
Fixed drug eruption (localised inflamed skin)

From: 5, Guideline summary

Cover of Drug Allergy
Drug Allergy: Diagnosis and Management of Drug Allergy in Adults, Children and Young People.
NICE Clinical Guidelines, No. 183.
National Clinical Guideline Centre (UK).
Copyright © National Clinical Guideline Centre, 2014.

NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.