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Adam MP, Feldman J, Mirzaa GM, et al., editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2023.

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GeneReviews® [Internet].

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Figure 1.

Figure 1.

Café au lait skin pigmentation

A. Skin lesions in a newborn demonstrating the characteristic association with the midline of the body, and distribution reflecting patterns of embryonic cell migration (developmental lines of Blaschko)

B. A typical lesion on the chest, face, and arm demonstrating the irregular "coast of Maine" borders, relationship with the midline of the body, and distribution following developmental lines of Blaschko

C. Typical lesions frequently found on the nape of the neck and crease of the buttocks

From: Fibrous Dysplasia / McCune-Albright Syndrome

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