Table 6.

Recommended Surveillance for Individuals with Legius Syndrome

System/ConcernEvaluationFrequency
Development Monitor developmental progress & educational needs.At each visit
Psychiatric/Behavioral Behavioral assessment for ADHD
Vascular anomalies 1 Blood pressure assessment

ADHD = attention-deficit/hyperactivity disorder

1.

Although vascular abnormalities have been reported in a few individuals with Legius syndrome, hypertension has not been reported. However, given the prevalence of vascular abnormalities and hypertension in NF1, it would seem appropriate to have regular blood pressure monitoring at each physician visit.

From: Legius Syndrome

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