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Ustekinumab (Stelara) [Internet]. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2017 Apr.
Drug | Ustekinumab (Stelara) |
---|---|
Indication | For the treatment of adult patients with moderately to severely active Crohn’s disease who have had an inadequate response, loss of response to, or were intolerant to either immunomodulators or one or more tumour necrosis factor-alpha antagonists, or have had an inadequate response, intolerance or demonstrated dependence on corticosteroids. |
Reimbursement request | As per indication. |
Dosage form(s) | 130 mg solution for intravenous infusion (for induction period) 90 mg solution for subcutaneous injection (for maintenance period) |
NOC Date | December 12, 2016 |
Manufacturer | Janssen Inc. |
Contents
- ABBREVIATIONS
- EXECUTIVE SUMMARY
- 1. INTRODUCTION
- 2. OBJECTIVES AND METHODS
- 3. RESULTS
- 4. DISCUSSION
- 5. CONCLUSIONS
- APPENDIX 1. PATIENT INPUT SUMMARY
- APPENDIX 2. LITERATURE SEARCH STRATEGY
- APPENDIX 3. EXCLUDED STUDIES
- APPENDIX 4. DETAILED OUTCOME DATA
- APPENDIX 5. VALIDITY OF OUTCOME MEASURES
- APPENDIX 6. SUMMARY OF THE IM-UNITI EXTENSION STUDY
- APPENDIX 7. SUMMARY OF INDIRECT COMPARISONS
- REFERENCES
- Clinical Review Report - Ustekinumab (Stelara)Clinical Review Report - Ustekinumab (Stelara)
- Onychostoma macrolepisOnychostoma macrolepisGenome
- OBJECTIVES AND METHODS - Ustekinumab (Stelara)OBJECTIVES AND METHODS - Ustekinumab (Stelara)
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