Table 6.

Recommended Surveillance for Individuals with Cold-Induced Sweating Syndrome / Crisponi Syndrome (CISS/CS)

  • Nutritionist to evaluate growth parameters to assess success of feeding strategies
  • Gastroenterologist eval may be required for assistance w/feeding or aspiration concerns.
Neurologist follow up for seizures if present & for neurologic status & development2x/yr or as needed
& speech delay
Neurodevelopmental eval to assess hand skills, speech development, oromotor skills (eating & chewing) & psychological adjustment
Corneal injury Ophthalmologic eval1-2x/yr
Physiotherapist examEvery 3 mos
Rash &
sweating issues
Monitoring by dermatologistAs required
Dental decay Dental examAnnually or as directed
Scoliosis Orthopedic eval2x/yr starting at end of 1st decade

From: Cold-Induced Sweating Syndrome Including Crisponi Syndrome

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