Structured Abstract

Contents

• Key Messages
• Preface
• Acknowledgments
• Technical Expert Panel
• Peer Reviewers
• Evidence Summary
  • Background
  • Methods
  • Results
  • Discussion
  • Conclusions
  • References
• Introduction
  • Background
• Methods
  • Search Strategy
  • Criteria for Inclusion/Exclusion of Studies in the Review
  • Study Selection
  • Data Abstraction and Data Management
  • Assessment of Methodological Risk of Bias of Individual Studies
  • Data Analysis and Synthesis
  • Grading the Strength of Evidence for Major Comparisons and Outcomes
  • Assessing Applicability
  • Managing Bias and the Appearance of Bias
  • Peer Review and Public Commentary
• Results
  • Literature Search Yield
  • Description of Included Studies
  • Overview
  • Key Question 1. Measures of Circulatory Compromise
  • Key Question 2. Measures of Respiratory Compromise
  • Key Question 3. Combination Measures
  • Key Questions 1a, 2a, and 3a. Differences Across Age Groups
• Discussion
  • Key Findings
  • Findings in Relationship to What Is Already Known
  • Applicability
  • Limitations of the Evidence Base
  • Limitations of the Review Process
  • Future Research Needs
  • Implications
  • Conclusions
• References
• Abbreviations and Acronyms
• Appendixes
  • Appendix A. Search Strategies
  • Appendix B. List of Included Studies
  • Appendix C. List of Excluded Studies
  • Appendix D. Evidence Tables
  • Appendix E. Risk of Bias Criteria
  • Appendix F. Risk of Bias Assessment
  • Appendix G. Multivariate Results Summaries
  • Appendix H. Strength of Evidence
  • Appendix I. Meta-Analysis Results for Studies of Predictive Utility in the Emergency Department Setting

Suggested citation:

Totten AM, Cheney TP, O’Neil ME, Newgard CD, Daya M, Fu R, Wasson N, Hart EL, Chou R. Physiologic Predictors of Severe Injury: Systematic Review. Comparative Effectiveness Review No. 205. (Prepared by the Pacific Northwest Evidence-based Practice Center under Contract No. 290-2015-00009-I.) AHRQ Publication No. 18-EHC008-EF. Rockville, MD: Agency for Healthcare Research and Quality; April 2018. Posted final reports are located on the Effective Health Care Program search page. DOI: https://doi.org/10.23970/AHRQEPCCER205.

This report is based on research conducted by the Pacific Northwest Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-2015-00009-I). The findings and conclusions in this document are those of the authors, who are responsible for its contents; the findings and conclusions do not necessarily represent the views of AHRQ. Therefore, no statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.

None of the investigators have any affiliations or financial involvement that conflicts with the material presented in this report.

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