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Przulj D, Pesola F, Myers Smith K, et al. Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy. Southampton (UK): National Institute for Health and Care Research; 2023 Jul. (Health Technology Assessment, No. 27.13.)

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Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy.

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References

1.
Royal College of Physicians. Smoking and the Young. A Report of a Working Party of the Royal College of Physicians. London: Royal College of Physicians; 1992.
2.
Godfrey C, Pickett K, Parrot S, Eapen S. Estimating the Costs to the NHS of Smoking in Pregnancy for Pregnant Women and Infants. York: University of York, Public Health Research Consortium; 2010.
3.
McAndrew F, Thompson J, Fellows L, Large A, Speed M, Renfrew MJ. Infant Feeding Survey 2010. Leeds: Health and Social Care Information Centre; 2012.
4.
Gray R, Bonellie SR, Chalmers J, Greer I, Jarvis S, Kurinczuk JJ, et al. Contribution of smoking during pregnancy to inequalities in stillbirth and infant death in Scotland 1994–2003: retrospective population based study using hospital maternity records. BMJ 2009;339:b3754. [PMC free article: PMC2755727] [PubMed: 19797343]
5.
Chamberlain C, O’Mara-Eves A, Oliver S, Caird JR, Perlen SM, Eades SJ, et al. Psychosocial interventions for supporting women to stop smoking in pregnancy. Cochrane Database Syst Rev 2013;10:CD001055. [PMC free article: PMC4022453] [PubMed: 24154953]
6.
Hajek P, West R, Lee A, Foulds J, Owen L, Eiser JR, Main N. Randomized controlled trial of a midwife-delivered brief smoking cessation intervention in pregnancy. Addiction 2001;96(3):485–94. [PubMed: 11255587]
7.
Coleman T, Chamberlain C, Davey MA, Cooper SE, Leonardi-Bee J. Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev 2012;9:CD010078. [PubMed: 22972148]
8.
National Institute for Health and Care Excellence (NICE). Smoking Cessation Interventions in Acute and Maternity Services: Review of Barriers and Facilitators. London: NICE; 2013.
9.
Lumley J, Chamberlain C, Dowswell T, Oliver S, Oakley L, Watson L. Interventions for promoting smoking cessation during pregnancy. Cochrane Database Syst Rev 2009;3:CD001055. [PMC free article: PMC4090746] [PubMed: 19588322]
10.
Ussher M, Lewis S, Aveyard P, Manyonda I, West R, Lewis B, et al. Physical activity for smoking cessation in pregnancy: randomised controlled trial. BMJ 2015;350:h2145. [PMC free article: PMC4431606] [PubMed: 25976288]
11.
Tappin D, Bauld L, Purves D, Boyd K, Sinclair L, MacAskill S, et al. Financial incentives for smoking cessation in pregnancy: randomised controlled trial. BMJ 2015;350:h134. [PubMed: 25627664]
12.
Coleman T, Cooper S, Thornton JG, Grainge MJ, Watts K, Britton J, Lewis S. A randomized trial of nicotine-replacement therapy patches in pregnancy. N Engl J Med 2012;366(9):808–18. [PubMed: 22375972]
13.
Cooper S, Lewis S, Thornton JG, Marlow N, Watts K, Britton J, et al. The SNAP trial: a randomised placebo-controlled trial of nicotine replacement therapy in pregnancy–clinical effectiveness and safety until 2 years after delivery, with economic evaluation. Health Technol Assess 2014;18(54):1–128. [PMC free article: PMC4782812] [PubMed: 25158081]
14.
Smoking in England. Electronic Cigarettes in England – Latest Trends. 2015. URL: https:​//smokinginengland​.info/graphs/e-cigarettes-latest-trends (accessed 7 March 2023 and archived by Wayback Machine at: http://web​.archive.org​/web/20230307112153​/https://smokinginengland​.info/graphs/e-cigarettes-latest-trends).
15.
Hajek P, Goniewicz ML, Phillips A, Smith KM, West O, McRobbie H. Nicotine intake from electronic cigarettes on initial use and after 4 weeks of regular use. Nicotine Tob Res 2015;17(2):175–9. [PMC free article: PMC4892703] [PubMed: 25122503]
16.
Saddleson M, Kozlowski L, Giovino G, Goniewicz M, Mahoney M, Homish G, Arora A. Enjoyment and other reasons for electronic cigarette use: results from college students in New York. Addict Behav 2016;54:33–9. [PubMed: 26704429]
17.
Bullen C, Howe C, Laugesen M, McRobbie H, Parag V, Williman J, Walker N. Electronic cigarettes for smoking cessation: a randomised controlled trial. Lancet 2013;382(9905):1629–37. [PubMed: 24029165]
18.
McNeill, Brose L, Calder R, Hitchman S, Hajek P, McRobbie H. E-Cigarettes: An Evidence Update. London: Public Health England; 2015. [PubMed: 26338257]
19.
Hartmann-Boyce J, McRobbie H, Lindson N, Bullen C, Begh R, Theodoulou A, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev 2021;4(4):CD010216. [PMC free article: PMC8092424] [PubMed: 33913154]
20.
Balfour DJ, Benowitz NL, Colby SM, Hatsukami DK, Lando HA, Leischow SJ, et al. Balancing consideration of the risks and benefits of e-cigarettes. Am J Public Health 2021;111(9):1661–72. [PMC free article: PMC8589069] [PubMed: 34410826]
21.
Caponnetto P, Auditore R, Russo C, Cappello GC, Polosa R. Impact of an electronic cigarette on smoking reduction and cessation in schizophrenic smokers: a prospective 12-month pilot study. Int J Environ Res Public Health 2013;10(2):446–61. [PMC free article: PMC3635154] [PubMed: 23358230]
22.
Caponnetto P, Campagna D, Cibella F, Morjaria JB, Caruso M, Russo C, Polosa R. EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as tobacco cigarettes substitute: a prospective 12-month randomized control design study. PLOS ONE 2013;8(6):e66317. [PMC free article: PMC3691171] [PubMed: 23826093]
23.
Polosa R, Caponnetto P, Morjaria JB, Papale G, Campagna D, Russo C. Effect of an electronic nicotine delivery device (e-cigarette) on smoking reduction and cessation: a prospective 6-month pilot study. BMC Public Health 2011;11:786. [PMC free article: PMC3203079] [PubMed: 21989407]
24.
Hajek P, Corbin L, Ladmore D, Spearing E. Adding e-cigarettes to specialist stop-smoking treatment: City of London pilot project. J Addict Res Ther 2015;6:244.
25.
Health & Social Care Information Centre. Statistics on NHS Stop Smoking Services in England – April 2014 to March 2015. London: Health & Social Care Information Centre; 2015.
26.
Stead LF, Perera R, Bullen C, Mant D, Hartmann-Boyce J, Cahill K, et al. Nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev 2012;11:CD000146. [PubMed: 23152200]
27.
Farquhar B, Mark K, Terplan M, Chisolm MS. Demystifying electronic cigarette use in pregnancy. J Addict Med 2015;9(2):157–8. [PubMed: 25622121]
28.
Mark KS, Farquhar B, Chisolm MS, Coleman-Cowger VH, Terplan M. Knowledge, attitudes, and practice of electronic cigarette use among pregnant women. J Addict Med 2015;9(4):266–72. [PubMed: 25974378]
29.
England LJ, Anderson BL, Mahoney J, Coleman-Cowger VH, Melstrom P, Schulkin J. Screening practices and attitudes of obstetricians-gynecologists toward new and emerging tobacco products. Am J Obstet Gynecol 2014;211(6):695.e1–7. [PMC free article: PMC4602388] [PubMed: 24881828]
30.
Fish LJ, Peterson BL, Brouwer RJN, Lyna P, Oncken CA, Swamy GK, et al. Adherence to nicotine replacement therapy among pregnant smokers. Nicotine Tob Res 2009;11(5):514–8. [PMC free article: PMC2671460] [PubMed: 19351783]
31.
Dempsey D, Jacob P, Benowitz NL. Accelerated metabolism of nicotine and cotinine in pregnant smokers. J Pharmacol Exp Ther 2002;301(2):594–8. [PubMed: 11961061]
32.
Hajek P, Etter JF, Benowitz N, Eissenberg T, McRobbie H. Electronic cigarettes: review of use, content, safety, effects on smokers and potential for harm and benefit. Addiction 2014;109(11):1801–10. [PMC free article: PMC4487785] [PubMed: 25078252]
33.
Fahy SJ, Cooper S, Coleman T, Naughton F, Bauld L. Provision of smoking cessation support for pregnant women in England: results from an online survey of NHS stop smoking services for pregnant women. BMC Health Serv Res 2014;14(1):107. [PMC free article: PMC3975862] [PubMed: 24593130]
34.
Dejmek J, Solanský I, Benes I, Lenícek J, Srám RJ. The impact of polycyclic aromatic hydrocarbons and fine particles on pregnancy outcome. Environ Health Perspect 2000;108(12):1159–64. [PMC free article: PMC1240197] [PubMed: 11133396]
35.
McEwen A, Hajek P, McRobbie H, West R. Manual of Smoking Cessation: A Guide for Counsellors and Practitioners. Oxford: Blackwell Publishing; 2006.
36.
Jones M, Lewis S, Parrott S, Wormall S, Coleman T. Re-starting smoking in the postpartum period after receiving a smoking cessation intervention: a systematic review. Addiction 2016;111(6):981–90. [PMC free article: PMC6680353] [PubMed: 26990248]
37.
Whitemore R, Leonardi-Bee J, Naughton F, Sutton S, Cooper S, Parrott S, et al. Effectiveness and cost-effectiveness of a tailored text-message programme (MiQuit) for smoking cessation in pregnancy: study protocol for a randomised controlled trial (RCT) and meta-analysis. Trials 2019;20(1):280. [PMC free article: PMC6530023] [PubMed: 31118090]
38.
Fagerström K. Determinants of tobacco use and renaming the FTND to the Fagerström Test for Cigarette Dependence. Nicotine Tob Res 2011;14(1):75–8. [PubMed: 22025545]
39.
Hajek P, Phillips-Waller A, Przulj D, Pesola F, Myers Smith K, Bisal N, et al. A randomized trial of e-cigarettes versus nicotine-replacement therapy. N Engl J Med 2019;380(7):629–37. [PubMed: 30699054]
40.
West R, Hajek P, Stead L, Stapleton J. Outcome criteria in smoking cessation trials: proposal for a common standard. Addiction 2005;100(3):299–303. [PubMed: 15733243]
41.
Benowitz NL, Bernert JT, Foulds J, Hecht SS, Jacob IP, Jarvis MJ, et al. Biochemical verification of tobacco use and abstinence: 2019 update. Nicotine Tob Res 2020;22(7):1086–97. [PMC free article: PMC7882145] [PubMed: 31570931]
42.
Sullivan TR, White IR, Salter AB, Ryan P, Lee KJ. Should multiple imputation be the method of choice for handling missing data in randomized trials? Stat Methods Med Res 2018;27(9):2610–26. [PMC free article: PMC5393436] [PubMed: 28034175]
43.
White IR, Royston P, Wood AM. Multiple imputation using chained equations: issues and guidance for practice. Stat Med 2011;30(4):377–99. [PubMed: 21225900]
44.
R Core Team. R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing; 2013.
45.
Hajek P, West R. Commentary on Smolkowski et al. (2010): why is it important to assume that non-responders in tobacco cessation trials have relapsed? Addiction 2010;105(6):1016–7. [PubMed: 20659061]
46.
Beard E, Dienes Z, Muirhead C, West R. Using Bayes factors for testing hypotheses about intervention effectiveness in addictions research. Addiction 2016;111(12):2230–47. [PMC free article: PMC5111611] [PubMed: 27347846]
47.
StataCorp. Stata Statistical Software: Release 16. College Station, TX: StataCorp LLC; 2019.
48.
Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. BMC Med 2010;8(1):18. [PMC free article: PMC2860339] [PubMed: 20334633]
49.
Dienes Z. Using Bayes to get the most out of non-significant results. Front Psychol 2014;5:781. [PMC free article: PMC4114196] [PubMed: 25120503]
50.
Wisborg K, Henriksen TB, Jespersen LB, Secher NJ. Nicotine patches for pregnant smokers: a randomized controlled study. Obstet Gynecol 2000;96(6):967–71. [PubMed: 11084187]
51.
Oncken C, Dornelas EA, Kuo CL, Sankey HZ, Kranzler HR, Mead EL, Thurlow MSD. Randomized trial of nicotine inhaler for pregnant smokers. Am J Obstet Gynecol 2019;1(1):10–8. [PMC free article: PMC6677278] [PubMed: 31380506]
52.
Hotham ED, Gilbert AL, Atkinson ER. A randomised-controlled pilot study using nicotine patches with pregnant women. Addict Behav 2006;31(4):641–8. [PubMed: 15985339]
53.
Berlin I, Grangé G, Jacob N, Tanguy M-L. Nicotine patches in pregnant smokers: randomised, placebo controlled, multicentre trial of efficacy. BMJ 2014;348:g1622. [PMC free article: PMC3950302] [PubMed: 24627552]
54.
Ford A, Uny I, Lowes J, Naughton F, Cooper S, Coleman T, et al. A qualitative study of factors influencing adherence among pregnant women taking part in a trial of e-cigarettes for smoking cessation. Int J Environ Res Public Health 2021;18(2):430. [PMC free article: PMC7827544] [PubMed: 33430407]
55.
Myers Smith K, Phillips-Waller A, Pesola F, McRobbie H, Przulj D, Orzol M, Hajek P. E-cigarettes versus nicotine replacement treatment as harm reduction interventions for smokers who find quitting difficult: randomised controlled trial. Addiction 2021;117(1):224–33. [PubMed: 34187081]
56.
Jackson SE, Farrow E, Brown J, Shahab L. Is dual use of nicotine products and cigarettes associated with smoking reduction and cessation behaviours? A prospective study in England. BMJ Open 2020;10(3):e036055. [PMC free article: PMC7073794] [PubMed: 32179563]
57.
Czoli CD, Fong GT, Goniewicz ML, Hammond D. Biomarkers of exposure among ‘dual users’ of tobacco cigarettes and electronic cigarettes in Canada. Nicotine Tob Res 2019;21(9):1259–66. [PMC free article: PMC6698946] [PubMed: 30203076]
58.
McRobbie H, Phillips A, Goniewicz ML, Smith KM, Knight-West O, Przulj D, et al. Effects of switching to electronic cigarettes with and without concurrent smoking on exposure to nicotine, carbon monoxide, and acrolein. Cancer Prev Res (Phila) 2015;8(9):873–8. [PubMed: 26333731]
59.
McNeill A, Brose L, Calder R, Simonavicius E, Robson D. Vaping in England: An Evidence Update including Vaping for Smoking Cessation. February 2021. Public Health England. URL: https://assets​.publishing​.service.gov.uk​/government/uploads/system​/uploads/attachment_data​/file/962221​/Vaping_in_England​_evidence_update_February_2021.pdf (accessed 1 August 2022).
60.
Russo C, Cibella F, Mondati E, Caponnetto P, Frazzetto E, Caruso M, et al. Lack of substantial post-cessation weight increase in electronic cigarettes users. Int J Environ Res Public Health 2018;15(4):581. [PMC free article: PMC5923623] [PubMed: 29570695]
61.
Hajek P, Przulj D, Phillips-Waller A, Anderson R, McRobbie H. Initial ratings of different types of e-cigarettes and relationships between product appeal and nicotine delivery. Psychopharmacology (Berl) 2018;235(4):1083–92. [PMC free article: PMC5869900] [PubMed: 29306962]
62.
Huang J, Duan Z, Kwok J, Binns S, Vera LE, Kim Y, et al. Vaping versus JUULing: how the extraordinary growth and marketing of JUUL transformed the US retail e-cigarette market. Tob Control 2019;28(2):146–51. [PMC free article: PMC6274629] [PubMed: 29853561]
63.
Phillips-Waller A, Przulj D, Smith KM, Pesola F, Hajek P. Nicotine delivery and user reactions to Juul EU (20 mg/ml) compared with Juul US (59 mg/ml), cigarettes and other e-cigarette products. Psychopharmacology (Berl) 2021;238(3):825–31. [PMC free article: PMC7914237] [PubMed: 33270145]
64.
Hajek P, Goniewicz ML, Phillips A, Myers Smith K, West O, McRobbie H. Nicotine intake from electronic cigarettes on initial use and after 4 weeks of regular use. Nicotine Tob Res 2015;17(2):175–9. [PMC free article: PMC4892703] [PubMed: 25122503]
65.
Wang X, Lee NL, Burstyn I. Smoking and use of electronic cigarettes (vaping) in relation to preterm birth and small-for-gestational-age in a 2016 US national sample. Prev Med 2020;134:106041. [PubMed: 32105682]
66.
Regan AK, Bombard JM, O’Hegarty MM, Smith RA, Tong VT. Adverse birth outcomes associated with prepregnancy and prenatal electronic cigarette use. Obstet Gynecol 2021;138(1):85–94. [PubMed: 34259468]
67.
McDonnell B, Dicker P, Regan C. Electronic cigarettes and obstetric outcomes: a prospective observational study. BJOG 2020;127(6):750–6. [PubMed: 32036628]
68.
Froggatt S, Reissland N, Covey J. The effects of prenatal cigarette and e-cigarette exposure on infant neurobehaviour: a comparison to a control group. EClinicalMedicine 2020;28:100602. [PMC free article: PMC7700948] [PubMed: 33294816]
69.
Cooper S, Taggar J, Lewis S, Marlow N, Dickinson A, Whitemore R, Coleman T, et al. Effect of nicotine patches in pregnancy on infant and maternal outcomes at 2 years: follow-up from the randomised, double-blind, placebo-controlled SNAP trial. Lancet Respir Med 2014;2(9):728–37. [PubMed: 25127405]
70.
Iyen B, Vaz LR, Taggar J, Cooper S, Lewis S, Coleman T. Is the apparently protective effect of maternal nicotine replacement therapy (NRT) used in pregnancy on infant development explained by smoking cessation?: secondary analyses of a randomised controlled trial. BMJ Open 2019;9(7):e024923. [PMC free article: PMC6629395] [PubMed: 31300493]
71.
Osborne JB. Does it matter when I quit? Could I just cut down some? Links between trimester-specific smoking amount, preterm birth, and low birth weight. Birth Defects Res 2021;114(1):5–12. [PubMed: 34585853]
72.
Hartmann-Boyce J, McRobbie H, Butler AR, Lindson N, Bullen C, Begh R, et al. Electronic cigarettes for smoking cessation. Cochrane Database Syst Rev 2021;9(9):CD010216. [PMC free article: PMC8438601] [PubMed: 34519354]
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