Appendix DStrength-of-Evidence Assessments

KQ 1 and KQ 2

Table D-1. Acamprosate compared with placebo for Key Questions 1 and 2 (MS Word, 82K)

Table D-2. Disulfiram compared with control for Key Questions 1 and 2 (MS Word, 75K)

Table D-3. Naltrexone (any dose and delivery) compared with placebo for Key Questions 1 and 2 (MS Word, 89K)

Table D-4. Oral naltrexone (50 mg) compared with placebo for Key Questions 1 and 2 (MS Word, 75K)

Table D-5. Oral naltrexone (100 mg) compared with placebo for Key Questions 1 and 2 (MS Word, 75K)

Table D-6. Injectable naltrexone compared with placebo for Key Questions 1 and 2 (MS Word, 78K)

Table D-7. Baclofen compared with placebo for Key Questions 1 and 2 (MS Word, 79K)

Table D-8. Gabapentin compared with placebo for Key Questions 1 and 2 (MS Word, 75K)

Table D-9. Ondansetron compared with placebo for Key Questions 1 and 2 (MS Word, 75K)

Table D-10. Prazosin compared with placebo for Key Questions 1 and 2 (MS Word, 75K)

Table D-11. Topiramate compared with placebo for Key Questions 1 and 2 (MS Word, 79K)

Table D-12. Varenicline compared with placebo for Key Questions 1 and 2 (MS Word, 76K)

Table D-13. Acamprosate compared with disulfiram for Key Questions 1 and 2 (MS Word, 76K)

Table D-14. Acamprosate compared with naltrexone for Key Questions 1 and 2 (MS Word, 84K)

Table D-15. Disulfiram compared with naltrexone for Key Questions 1 and 2 (MS Word, 80K)

Table D-16. Topiramate compared with naltrexone for Key Questions 1 and 2 (MS Word, 76K)

KQ 3

Table D-17. Acamprosate compared with placebo for Key Question 3 (MS Word, 77K)

Table D-18. Disulfiram compared with placebo or control for Key Question 3 (MS Word, 80K)

Table D-19. Naltrexone compared with placebo for Key Question 3 (MS Word, 77K)

Table D-20. Baclofen compared with placebo for Key Question 3 (MS Word, 76K)

Table D-21. Gabapentin compared with placebo for Key Question 3 (MS Word, 77K)

Table D-22. Ondansetron compared with placebo for Key Question 3 (MS Word, 77K)

Table D-23. Prazosin compared with placebo for Key Question 3 (MS Word, 77K)

Table D-24. Topiramate compared with placebo for Key Question 3 (MS Word, 76K)

Table D-25. Varenicline compared with placebo for Key Question 3 (MS Word, 77K)

Table D-26. Acamprosate compared with disulfiram for Key Question 3 (MS Word, 82K)

Table D-27. Acamprosate compared with naltrexone for Key Question 3 (MS Word, 76K)

Table D-28. Disulfiram compared with naltrexone for Key Question 3 (MS Word, 78K)