From: Childhood Hodgkin Lymphoma Treatment (PDQ®)
PDQ Cancer Information Summaries [Internet].
Bethesda (MD): National Cancer Institute (US); 2002-.
NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health.
Table 3. Children's Oncology Group and EuroNet Definition of PET Response of Lymph Node or Nodal Masses
| Timing of 18F-FDG PET | 18F-FDG PET Avidity |
|---|---|
| Baseline PET (PET 0) response visual threshold utilizes mediastinal blood pool as the reference activity: | 18F-FDG PET positive is defined as visual score 3, 4, 5. |
| 18F-FDG PET negative is defined as visual score 1, 2. | |
| Interim postcycle 2 PET (PET 2) response visual threshold uses normal liver as the reference activity: | 18F-FDG PET positive is defined as visual score 4, 5. |
| 18F-FDG PET negative is defined as visual score 1, 2, 3. | |
| End of chemotherapy PET (PET 4 or 5) response visual threshold also utilizes mediastinal blood pool as the reference activity: | 18F-FDG PET positive is defined as visual score 3, 4, 5. |
| 18F-FDG PET negative is defined as visual score 1, 2. |
18F-FDG = fluorine F 18-fludeoxyglucose; PET = positron emission tomography.