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McCrory DC, Coeytaux RR, Yancy WS Jr, et al. Assessment and Management of Chronic Cough [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 Jan. (Comparative Effectiveness Reviews, No. 100.)

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Assessment and Management of Chronic Cough [Internet].

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Appendix DExcluded Studies

All studies listed below were reviewed in their full-text version and excluded for the reasons cited. Reasons for exclusion signify only the usefulness of the articles for this study and are not intended as criticisms of the articles.

Full text not available

  1. Abramson MJ, Schattner RL, Holton C, et al. Spirometry and regular follow-up do not improve outcomes in children or adolescents with asthma. Respirology. 2012;17:50.
  2. Agondi R, Kalil J, Giavina-Bianchi P. Gastroesophageal reflux in patients with chronic cough. Journal of Allergy and Clinical Immunology. 2012;129(2):AB9.
  3. Albloushi A, Simpson S, Stick S, et al. Feasibility and safety of mannitol challenge in pre-school children using forced oscilations. Respirology. 2012;17:4.
  4. Boom L, Vaessen D, Uil S, et al. The effects of montelukast in patients with chronic cough and bronchial hyperreactivity. Chest. 2011;140(4)
  5. Cheng CL, Kao YHY, Lin SJ. Safety and cough and cold medicines in children in Taiwan. Pharmacoepidemiology and Drug Safety. 2011;20:S318–319.
  6. Dockry RJ, Sunger K, Marsden P, et al. Investigating patterns in 24 hours of coughing. Thorax. 2011;66:A65.
  7. Kerwin E, Tashkin DP, Matiz-Bueno CE, et al. Clinical efficacy and safety of combined mometasone furoate and formoterol in patients with moderate to very severe chronic obstructive pulmonary disease (COPD). Journal of Allergy and Clinical Immunology. 2012;129(2):AB201. [PMC free article: PMC3276256] [PubMed: 22334768]
  8. Khalid S, Dockry R, Holt K, et al. Cough responses to tussive agents in health and disease. Thorax. 2011;66:A64.
  9. Kurasirikul S, Vichyanond P, Piboonpocanun O, et al. Efficacy of gentamicin nasal irrigation in chronic rhinosinusitis in children. Journal of Allergy and Clinical Immunology. 2012;129(2):AB44.
  10. Lake C, Briffa P, Munoz P, et al. Documentation of cough provoked during a mannitol challenge using acoustic respiratory monitoring compared to video surveillance monitoring. Repriology. 2012;17:1.
  11. Lee KK, Matos S, Evans DH, et al. Predictors of 24-H cough frequency in acute cough. Thorax. 2011;66:A64.
  12. Li Y, Wang H. 100 Cases of children cough and gasp treated by fire needling. Chinese Journal of Acupuncture and Moxibustion. 1991;4(2):117–118.
  13. Maesen F, Smeets J, Hoogslag MA. Azipranone (RU 20.201), a new cough suppressant. A clinical trial using objective and subjective parameters. Tijdschrift voor Geneesmiddelenonderzoek. 1983;8(7):1941–1944.
  14. Perrem LM, O'Neill MB. Can questionnaire completion, by parents, obviate the need for outpatient assessments of their children with respiratory diseases? Irish Journal of Medical Science. 2011;180:S452.
  15. Quittner A, Marciel K, Kimberg C, et al. Content validity of a disease-specific patient-reported outcome for bronchiectasis. Chest. 2011;140(4)
  16. Saini G, McKeever T, Johnson S, et al. Thalidomide as treatment for IPF associated cough. Thorax. 2011;66:A103.
  17. Smith SM, MacAuslan J, Goldhor R, et al. Using acoustic analysis of coughs to identify respiratory infections in the emergency department. Academic Emergency Medicine. 2012;19:S302.
  18. Spector S, Tan R, Lee R. Cough vs wheezing during methacholine challenge. Chest. 2011;140(4)
  19. Usta Guc B, Asilsoy S, Durmaz C. Bronchial hyperactivity in children with chronic cough. Allergy: European Journal of Allergy and Clinical Immunology. 2011;66:199.
  20. Usta Guc B, Asilsoy S, Durmaz C. Bronchial hyperactivity in patients with rhinitis who consulted due to chronic cough. Allergy: European Journal of Allergy and Clinical Immunology. 2011;66:199.
  21. Vertigan A, Gibson P. Development of a brief speech pathology intervention for chronic refractory cough. Pulmonary Pharmacology and Therapeutics. 2011;24(3):e5.
  22. Willis C, Robertson CF, Van Asperen PP, et al. A multi-centre study on chronic cough: burden and etiologies based on a standardized management pathway. Respirology. 2012;17:79. [PubMed: 22459773]
  23. Zanasi A, Lanata L, De Danieli G, et al. Cough incidence, impact on sleep, and antitussive treatment in the pediatric population. Chest. 2011;140(4)
  24. Zhang Y. The values of fractional exhaled nitric oxide in the diagnosis and treatment of chronic cough. Respirology. 2011;16:213. [PubMed: 22041775]

Non-English language

  1. Adamko DJ, Majaesic CM, Skappak C, et al. A pilot on the treatment of gastroesophageal reflux-related cough in infants. Zhongguo Dang Dai Er Ke Za Zhi. 2012;14(5):321–7. [PubMed: 22613099]
  2. Carrasquer A, Targarona EM, Mannello F, et al. Laparoscopic fundoplication results in the treatment of the non-gastrointestinal symptoms of gastroesophageal reflux. Cir Esp. 2012;90(4):238–42. [PubMed: 22404897]
  3. Ghaffari J, Saffar M, Salehifar E, et al. Anti-cough effects of tramadol in patients with pertussis. Journal of Mazaridaran University of Medical Sciences. 2011;21(84):106–111.
  4. Ghodrati S, Hormati A, Mousavi NN, et al. Comparison of FEV1 and PEF values in cough variant asthma during methacholine challenge test. Journal of Zanjan University of Medical Sciences and Health Services. 2011;19(77):3.
  5. Ghodrati S, Mousavinasab SN, Pezeshki B, et al. Prevalence of cough variant asthma in patients with chronic cough attending to Vali-e Asr hospital of Zanjan, Iran, 2009. Journal of Zanjan University of Medical Sciences and Health Services. 2011;19(76)
  6. Kardos P, Gebhardt T. Chronic persistent cough (CPH) in the medical practice: Diagnostics and treatment of 329 patients in 2 years. Pneumologie. 1996;50(6):437–441. [PubMed: 8766375]
  7. Pacheco A, Faro V, Cobeta I, et al. Chronic cough with limited response to treatment and incidence of gastroesophageal reflux. Archivos de Bronconeumologia. 2012;48(6):197–201. [PubMed: 22421522]
  8. Zhang YM, Lin JT. The values of fractional exhaled nitric oxide for the diagnosis and treatment response evaluation of chronic cough. Respirology. 2011;16:219.

Study population is not human

  1. Chakraborty D, Shah B. Antimicrobial, anti-oxidative and anti-hemolytic activity of Piper betel leaf extracts. International Journal of Pharmacy and Pharmaceutical Sciences. 2011;3(SUPPL. 3):192–199.
  2. Harsanyi K, Tardos L, Feher I, et al. Pharmacologic, clinico-pharmacologic and clinical effects of Libexin. Boll Chim Farm. 1973;112(10):691–9. [PubMed: 4782264]
  3. Schneider CR, Everett AW, Geelhoed E, et al. Provision of primary care to patients with chronic cough in the community pharmacy setting. Ann Pharmacother. 2011;45(3):402–8. [PubMed: 21325099]

Not an evaluation study (KQ 1), RCT (KQ1 or KQ2), cohort study (KQ1 or KQ2)

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  11. Anonymous. Prolonged and chronic cough. Respirology. 2006;11(Suppl 4):S160–S174.
  12. Anonymous. Evaluation of cough. Respirology. 2006;11(Suppl 4):S143–S148.
  13. Anonymous. Acute cough. Respirology. 2006;11(Suppl 4):S152–S159.
  14. Anonymous. Cough in specific populations (paediatric patients, elderly patients and patients with underlying disease). Respirology. 2006;11(Suppl 4):S175–S186.
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Study population does not have cough (KQ 1) or chronic cough (KQ 2)

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No intervention of interest OR the intervention is intended to treat the underlying etiology

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No outcomes of interest

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No comparator

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