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Berkman ND, Wallace IF, Steiner MJ, et al. Otitis Media With Effusion: Comparative Effectiveness of Treatments [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 May. (Comparative Effectiveness Reviews, No. 101.)
This publication is provided for historical reference only and the information may be out of date.
PubMed:
Search Jan. 8, 2012
| Search | Query | Items found |
|---|---|---|
| #1 | Search "Otitis Media with Effusion"[Mesh] | 4535 |
| #2 | Search "Ear, Middle/secretion"[Mesh] | 101 |
| #3 | Search "glue ear"[tiab] | 251 |
| #4 | Search "otitis media"[tiab] | 15150 |
| #5 | Search middle ear effusion* | 1609 |
| #6 | Search (OME[tiab] OR SOM[tiab]) AND (otitis[tiab] OR ear*[tiab]) | 1463 |
| #7 | Search "nonsuppurative otitis"[tiab] | 0 |
| #8 | Search "serous otitis"[tiab] | 610 |
| #9 | Search "secretory otitis"[tiab] | 940 |
| #10 | Search "adhesive otitis"[tiab] | 165 |
| #11 | Search "exudative otitis"[tiab] | 89 |
| #12 | Search (mucoid*[tiab] AND otitis[tiab]) OR (mucous[tiab] AND otitis[tiab]) OR (sero-muco*[tiab] AND otitis[tiab]) OR (sero[tiab] OR muco[tiab] AND otitis[tiab]) OR (otitis[tiab] AND serosa[tiab]) | 412 |
| #13 | Search (mucoid*[tiab] AND middle[tiab] AND ear*[tiab]) OR (mucous[tiab] AND middle[tiab] AND ear*[tiab]) OR (seromuc*[tiab] AND middle[tiab] AND ear*[tiab]) | 462 |
| #14 | Search #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 | 17356 |
| #15 | Search "Steroids"[Mesh] OR oral steroid* | 653912 |
| #16 | Search nasal*[tiab] AND (topical steroid*[tiab]) | 213 |
| #17 | Search "Anti-Bacterial Agents"[Mesh] OR antibiotic* | 367969 |
| #18 | Search "ear popper"[tiab] OR manual therap*[tiab] | 965 |
| #19 | Search autoinflation[tiab] | 49 |
| #20 | Search pressure equalization tube*[tiab] | 58 |
| #21 | Search "Adenoidectomy"[Mesh] OR adenoidectom*[tiab] | 3873 |
| #22 | Search "Middle Ear Ventilation"[Mesh] OR tympanostomy[tiab] OR ((middle[tiab] AND (ear*[tiab] OR tympanic[tiab])) AND tube*[tiab]) | 4130 |
| #23 | Search grommet*[tiab] | 445 |
| #24 | Search ventilation tube*[tiab] | 777 |
| #25 | Search "Tonsillectomy"[Mesh] OR tonsillectomy[tiab] | 8554 |
| #26 | Search "Leukotriene Antagonists/therapeutic use"[Mesh] OR "Leukotriene Antagonists" [Pharmacological Action] | 4042 |
| #27 | Search "Acetates/therapeutic use"[Mesh] | 2774 |
| #28 | Search "Quinolines/therapeutic use"[Mesh] | 35055 |
| #29 | Search "Combined Modality Therapy"[Mesh] OR combined modality therap*[tiab] | 177569 |
| #30 | Search myringotomy[tiab] | 1061 |
| #31 | Search "Otologic Surgical Procedures"[Mesh] | 13165 |
| #32 | Search "Phosphorylcholine/administration and dosage"[Mesh] OR "Phosphorylcholine/therapeutic use"[Mesh] | 412 |
| #33 | Search "Watchful Waiting"[Mesh] OR watchful waiting*[tiab] | 1517 |
| #34 | Search tubulation[tiab] | 257 |
| #35 | Search #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #31 or #32 or #33 or #34 | 1231827 |
| #36 | Search #14 and #35 | 6961 |
| #37 | Search #36 or #30 | 7507 |
| #38 | Search #37 Limits: Humans | 6659 |
| #39 | Search "Randomized Controlled Trial"[Publication Type] OR "Single-Blind Method"[MeSH] OR "Double-Blind Method"[MeSH] OR "Random Allocation"[MeSH] | 398253 |
| #40 | Search #38 and #39 | 602 |
| #41 | Search #38 Limits: Controlled Clinical Trial | 70 |
| #42 | Search #38 AND "Controlled Clinical Trials as Topic"[Mesh] | 134 |
| #43 | Search #40 or #41 or #42 | 763 |
| #44 | Search #38 AND systematic[sb] | 258 |
| #45 | Search #38 Limits: Meta-Analysis | 55 |
| #46 | Search #44 or #45 | 258 |
| #47 | Search ("Case-Control Studies"[MeSH] OR "Cohort Studies"[MeSH] OR "Epidemiologic Studies"[MeSH] OR "Cross-Sectional Studies"[MeSH] OR "Organizational Case Studies"[MeSH] OR "Cross-Over Studies"[MeSH] OR "Follow-Up Studies"[MeSH] OR "Seroepidemiologic Studies"[MeSH] OR "Multicenter Study"[Publication Type] OR “Multicenter Studies as Topic”[MeSH] OR "Evaluation Studies"[Publication Type] OR “Evaluation Studies as Topic”[MeSH]) | 2315890 |
| #48 | Search #38 and #47 | 2603 |
| #49 | Search #38 and harms | 5 |
| #50 | Search #43 or #46 or #48 or #49 ALL STUDY TYPES GATHERED EXCEPT LIT REVIEWS, SAVED SEPARATELY. | 2939 |
| #51 | Search #38 Limits: Review | 979 |
| #52 | Search #51 not #46 THE LIT. REVIEWS. | 851 |
Cochrane Library:
Search Jan. 8, 2012
| ID | Search | Hits |
|---|---|---|
| #1 | "Otitis Media with Effusion" OR "otitis media" OR "middle ear secretion" OR "Ear, Middle/secretion" OR "glue ear" OR middle ear effusion* OR OME OR SOM OR (otitis AND ear) OR (otitis AND ears) OR "nonsuppurative otitis" OR "serous otitis" OR "secretory otitis" OR "adhesive otitis" OR "exudative otitis" OR (mucoid AND otitis) OR (mucous AND otitis) OR (sero-muco* AND otitis) OR ((sero OR muco) AND otitis) OR (otitis AND serosa) OR (mucoid AND middle AND ear*) OR (mucous AND middle AND ear*) OR (seromuc* AND middle AND ear*) | 2221 |
| #2 | "Steroids" OR oral steroid* OR (nasal* AND topical steroid*) OR "Anti-Bacterial Agents" OR antibiotic* OR "ear popper" OR manual therap* OR pressure equalization tube* OR adenoidectom* OR "Middle Ear Ventilation" OR tympanostomy OR (middle AND ear*AND tube*) OR (middle AND tympanic* AND tube*) OR grommet* OR ventilation tube* OR tonsillectomy OR "Leukotriene Antagonists/therapeutic use" OR "Leukotriene Antagonists" OR acetate* OR quinolone* OR phosphorylcholine OR combined modality therap* OR "Otologic Surgical Procedures" OR watchful waiting* OR tabulation OR autoinflation | 50759 |
| #3 | (#1 AND #2) | 1023 |
| #4 | (#3 OR myringotomy) | 1119 |
| #5 | "Randomized Controlled Trial" OR "Single-Blind Method" OR "Double-Blind Method" OR "Random Allocation" OR "Controlled Clinical Trial" OR "Controlled Clinical Trials as Topic" OR (control* AND trial) | 689256 |
| #6 | (#4 AND #5) | 1067 |
| #7 | ("Case-Control Studies"[MeSH] OR "Cohort Studies"[MeSH] OR "Epidemiologic Studies"[MeSH] OR "Cross-Sectional Studies"[MeSH] OR "Organizational Case Studies"[MeSH] OR "Cross-Over Studies"[MeSH] OR "Follow-Up Studies"[MeSH] OR "Seroepidemiologic Studies"[MeSH] OR "Multicenter Study"[Publication Type] OR "Multicenter Studies as Topic"[MeSH] OR "Evaluation Studies"[Publication Type] OR "Evaluation Studies as Topic"[MeSH]) | 120400 |
| #8 | (#4 AND #7) | 308 |
| #9 | (#4) | 172 |
| #10 | (#6 OR #8 OR #9) | 1119 |
Embase:
Search Jan. 8, 2012
| No. | Query | Results |
|---|---|---|
| #1 | 'otitis media with effusion'/exp OR 'otitis media with effusion' OR 'otitis media'/exp OR 'otitis media' OR 'middle ear secretion' OR 'ear, middle/secretion' OR 'glue ear'/exp OR 'glue ear' OR middle AND ('ear'/exp OR ear) AND effusion* OR ome OR som OR ('otitis'/exp OR otitis AND ('ear'/exp OR ear)) OR ('otitis'/exp OR otitis AND ears) OR 'nonsuppurative otitis' OR 'serous otitis'/exp OR 'serous otitis' OR 'secretory otitis' OR 'adhesive otitis' OR 'exudative otitis' OR (mucoid AND ('otitis'/exp OR otitis)) OR (mucous AND ('otitis'/exp OR otitis)) OR ('otitis'/exp OR otitis AND ('serosa'/exp OR serosa)) OR (mucoid AND middle AND ('ear'/exp OR ear)) OR (mucous AND middle AND ('ear'/exp OR ear)) AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) Bottom of Form Bottom of Form | 23,677 |
| #2 | 'steroids'/exp OR steroids OR 'oral'/exp OR oral AND steroid* OR (nasal* AND ('topical'/exp OR topical) AND ('steroid'/exp OR steroid)) OR 'antibacterial agents' OR 'anti-bacterial agents' OR antibiotic* OR autoinflation OR 'ear popper' OR manual AND ('therapy'/exp OR therapy) OR 'pressure'/exp OR pressure AND equalization AND ('tube'/exp OR tube) OR 'adenoidectomy'/exp OR adenoidectomy OR 'middle ear ventilation'/exp OR 'middle ear ventilation' OR tympanostomy OR (middle AND ('ear'/exp OR ear) AND ('tube'/exp OR tube)) OR (middle AND tympanic* AND tube*) OR grommet* OR 'ventilation'/exp OR ventilation AND ('tube'/exp OR tube) OR 'tonsillectomy'/exp OR tonsillectomy OR 'leukotriene antagonists/therapeutic use' OR 'leukotriene antagonists'/exp OR 'acetate'/exp OR acetate OR quinolone* OR 'phosphorylcholine'/exp OR phosphorylcholine OR combined AND modality AND ('therapy'/exp OR therapy) OR 'otologic surgical procedures'/exp OR 'otologic surgical procedures' OR watchful AND waiting OR tubulation AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) | 1,730 |
| #3 | #1 AND #2 | 96 |
| #4 | 'myringotomy'/exp OR myringotomy AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) | 1,989 |
| #5 | #3 OR #4 | 2,056 |
| #6 | #5 AND [review]/lim | 264 |
| #7 | 'randomized controlled trial'/exp OR 'single blind procedure'/exp OR 'double blind procedure'/exp OR 'random allocation' | 333,668 |
| #8 | #5 AND #7 | 140 |
| #9 | 'controlled clinical trial'/exp OR 'controlled clinical trial (topic)'/exp | 421,718 |
| #10 | #5 AND #9 | 162 |
| #11 | 'follow up'/exp | 602,436 |
| #12 | #5 AND #11 | 194 |
| #13 | 'systematic review'/exp OR 'meta analysis'/exp | 85,928 |
| #14 | #5 AND #13 | 36 |
| #15 | 'case control study'/exp OR 'cohort analysis'/exp OR 'epidemiological study' OR 'cross-sectional study'/exp OR 'organizational case study' OR 'crossover procedure'/exp OR 'seroepidemiologic study' OR 'epidemiology'/exp OR 'multicenter study'/exp OR 'multicenter study (topic)'/exp OR 'evaluation research'/exp | 1,850,275 |
| #16 | #5 AND #15 | 286 |
| #17 | #5 AND harms | 1 |
| #18 | #8 OR #10 OR #12 OR #14 OR #16 OR #17 | 4571 |
| #19 | #18 NOT #6 | 499 |
CINAHL:
Search Jan. 8, 2012
| # | Query | Limiters/Expanders | Last Run Via | Results |
|---|---|---|---|---|
| S35 | S34 NOT S8 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 126 |
| S34 | S14 or S16 or S18 or S20 or S32 or S33 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 126 |
| S33 | S6 AND harms | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 1 |
| S32 | S6 AND S31 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 93 |
| S31 | S21 or S22 or S23 or S24 or S25 or S26 or S27 or S28 or S29 or S30 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 228629 |
| S30 | (MH "Evaluation Research+") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 16072 |
| S29 | (MH "Multicenter Studies") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 5343 |
| S28 | (MH "Seroprevalence Studies") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 295 |
| S27 | (MH "Crossover Design") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 6732 |
| S26 | "organizational case studies" | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 3 |
| S25 | (MH "Cross Sectional Studies") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 45985 |
| S24 | (MH "Epidemiological Research") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 17482 |
| S23 | (MH "Prospective Studies+") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 124579 |
| S22 | (MH "Case Control Studies+") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 25256 |
| S21 | (MH "Observational Methods+") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 11878 |
| S20 | S6 and S19 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 8 |
| S19 | (MH "Meta Analysis") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 11090 |
| S18 | S6 and S17 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 7 |
| S17 | (MH "Systematic Review") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 9517 |
| S16 | S6 and S15 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 33 |
| S15 | "controlled clinical trial" OR (MH "Clinical Trials+") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 100728 |
| S14 | S6 and S13 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 22 |
| S13 | S9 or S10 or S11 or S12 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 46815 |
| S12 | (MH "Random Assignment") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 26792 |
| S11 | (MH "Double-Blind Studies") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 17004 |
| S10 | (MH "Single-Blind Studies") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 4748 |
| S9 | (MH "Randomized Controlled Trials") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 7500 |
| S8 | S6 and S7 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 9 |
| S7 | (MH "Literature Review+") | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 12381 |
| S6 | S5 | Limiters - Human Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 243 |
| S5 | S3 or S4 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 1475 |
| S4 | TX myringotomy | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 297 |
| S3 | S1 and S2 | Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 1237 |
| S2 | TX "Histamine Antagonists" OR antihistamine* OR "Steroids" OR oral steroid* OR (nasal* AND topical steroid*) OR "Anti-Bacterial Agents" OR antibiotic* OR complementary medicine* OR alternative medicine* OR complementary therap* OR alternative therap* OR "ear popper" OR manual therap* OR pressure equalization tube* OR adenoidectom* OR "Middle Ear Ventilation" OR tympanostomy OR (middle AND ear*AND tube*) OR (middle AND tympanic* AND tube*) OR grommet* OR ventilation tube* OR tonsillectomy OR "Leukotriene Antagonists/therapeutic use" OR "Leukotriene Antagonists" OR acetate* OR quinolone* OR phosphorylcholine OR combined modality therap* OR "Otologic Surgical Procedures" OR watchful waiting* OR tubulation | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 96206 |
| S1 | TX "Otitis Media with Effusion" OR "otitis media" OR "middle ear secretion" OR "Ear, Middle/secretion" OR "glue ear" OR middle ear effusion* OR OME OR SOM OR (otitis AND ear) OR (otitis AND ears) OR "nonsuppurative otitis" OR "serous otitis" OR "secretory otitis" OR "adhesive otitis" OR "exudative otitis" OR (mucoid AND otitis) OR (mucous AND otitis) OR (sero-muco* AND otitis) OR (sero AND otitis) OR (sero AND muco*) OR (otitis AND serosa) OR (mucoid AND middle AND ear*) OR (mucous AND middle AND ear*) OR (seromuc* AND middle AND ear*) | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | Interface - EBSCOhost Search Screen - Advanced Search Database - CINAHL with Full Text | 3096 |
PubMed supplemental search for CAM:
Search Feb 28, 2012
| Search | Query | Items found |
|---|---|---|
| #1 | Search "Otitis Media with Effusion"[Mesh] | 4555 |
| #2 | Search "Ear, Middle/secretion"[Mesh] | 101 |
| #3 | Search "glue ear"[tiab] | 251 |
| #4 | Search "otitis media"[tiab] | 15224 |
| #5 | Search middle ear effusion* | 1614 |
| #6 | Search (OME[tiab] OR SOM[tiab]) AND (otitis[tiab] OR ear*[tiab]) | 1471 |
| #7 | Search "serous otitis"[tiab] | 612 |
| #8 | Search "secretory otitis"[tiab] | 941 |
| #9 | Search "adhesive otitis"[tiab] | 166 |
| #10 | Search "exudative otitis"[tiab] | 89 |
| #11 | Search (mucoid*[tiab] AND otitis[tiab]) OR (mucous[tiab] AND otitis[tiab]) OR (sero-muco*[tiab] AND otitis[tiab]) OR (sero[tiab] OR muco[tiab] AND otitis[tiab]) OR (otitis[tiab] AND serosa[tiab]) | 414 |
| #12 | Search (mucoid*[tiab] AND middle[tiab] AND ear*[tiab]) OR (mucous[tiab] AND middle[tiab] AND ear*[tiab]) OR (seromuc*[tiab] AND middle[tiab] AND ear*[tiab]) | 463 |
| #13 | Search "nonsuppurative otitis"[tiab] | 0 |
| #14 | Search #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 | 17439 |
| #15 | Search "Complementary Therapies"[Mesh] | 155090 |
| #16 | Search "Diet, Sodium-Restricted"[Mesh] | 5155 |
| #17 | Search "Diet, Protein-Restricted"[Mesh] | 1621 |
| #18 | Search "Diet, Carbohydrate-Restricted"[Mesh] | 558 |
| #19 | Search "Diet, Fat-Restricted"[Mesh] | 2350 |
| #20 | Search "Dairy Products"[Mesh] | 66432 |
| #21 | Search dairy OR milk OR cream Or cheese OR butter | 130562 |
| #22 | Search #15 or #16 or #17 or #18 or #19 or #20 or #21 | 294555 |
| #23 | Search #14 and #22 | 230 |
| #24 | Search #23 Limits: Humans | 201 |
| #25 | Search "Randomized Controlled Trial"[Publication Type] OR "Single-Blind Method"[MeSH] OR "Double-Blind Method"[MeSH] OR "Random Allocation"[MeSH] | 401536 |
| #26 | Search #24 and #25 | 17 |
Cochrane Library supplemental search for CAM:
Search Feb 28, 2012
| ID | Search | Hits |
|---|---|---|
| #1 | "Otitis Media with Effusion" OR "otitis media" OR "middle ear secretion" OR "Ear, Middle/secretion" OR "glue ear" OR middle ear effusion* OR OME OR SOM OR (otitis AND ear) OR (otitis AND ears) OR "nonsuppurative otitis" OR "serous otitis" OR "secretory otitis" OR "adhesive otitis" OR "exudative otitis" OR (mucoid AND otitis) OR (mucous AND otitis) OR (sero-muco* AND otitis) OR ((sero OR muco) AND otitis) OR (otitis AND serosa) OR (mucoid AND middle AND ear*) OR (mucous AND middle AND ear*) OR (seromuc* AND middle AND ear*) | 2292 |
| #2 | MeSH descriptor Complementary Therapies explode all trees | 11569 |
| #3 | MeSH descriptor Diet, Sodium-Restricted explode all trees | 456 |
| #4 | MeSH descriptor Diet, Protein-Restricted explode all trees | 145 |
| #5 | MeSH descriptor Diet, Fat-Restricted explode all trees | 643 |
| #6 | MeSH descriptor Diet, Carbohydrate-Restricted explode all trees | 128 |
| #7 | MeSH descriptor Dairy Products explode all trees | 2342 |
| #8 | dairy OR milk OR cream Or cheese OR butter | 9224 |
| #9 | (#2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8) | 22097 |
| #10 | (#1 AND #9) | 86 |
| #11 | "Randomized Controlled Trial" OR "Single-Blind Method" OR "Double-Blind Method" OR "Random Allocation" OR "Controlled Clinical Trial" OR "Controlled Clinical Trials as Topic" OR (control* AND trial) | 698608 |
| #12 | (#10 AND #11) | 86 |
EMBASE supplemental search for CAM:
Search Feb 28, 2012
| No. | Query | Results |
|---|---|---|
| #1 | 'otitis media with effusion'/exp OR 'otitis media with effusion' OR 'otitis media'/exp OR 'otitis media' OR 'middle ear secretion' OR 'ear, middle/secretion' OR 'glue ear'/exp OR 'glue ear' OR middle AND ('ear'/exp OR ear) AND effusion* OR ome OR som OR ('otitis'/exp OR otitis AND ('ear'/exp OR ear)) OR ('otitis'/exp OR otitis AND ears) OR 'nonsuppurative otitis' OR 'serous otitis'/exp OR 'serous otitis' OR 'secretory otitis' OR 'adhesive otitis' OR 'exudative otitis' OR (mucoid AND ('otitis'/exp OR otitis)) OR (mucous AND ('otitis'/exp OR otitis)) OR ('otitis'/exp OR otitis AND ('serosa'/exp OR serosa)) OR (mucoid AND middle AND ('ear'/exp OR ear)) OR (mucous AND middle AND ('ear'/exp OR ear)) AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) | 23,921 |
| #2 | 'alternative medicine'/exp | 28,963 |
| #3 | 'sodium restriction'/exp | 7,519 |
| #4 | 'protein restriction'/exp | 5,671 |
| #5 | 'low carbohydrate diet'/exp | 1,083 |
| #6 | 'low fat diet'/exp | 5, 811 |
| #7 | 'dairy product'/exp | 74,303 |
| #8 | dairy OR 'milk'/exp OR 'cream'/exp OR 'cheese'/exp OR 'butter'/exp AND ([embase]/lim OR [embase classic]/lim) | 63,357 |
| #9 | #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 | 140,00 |
| #10 | #1 AND #9 | 129 |
| #11 | 'randomized controlled trial'/exp OR 'single blind procedure'/exp OR 'double blind procedure'/exp OR 'random allocation'/exp AND ([embase]/lim OR [embase classic]/lim) | 278.009 |
| #12 | #10 AND #11 | 6 |
CINAHL supplemental search for CAM:
Search Feb 28, 2012
| # | Query | Limiters/Expanders | Results |
|---|---|---|---|
| S17 | S11 and S16 | Search modes - Boolean/Phrase | |
| S16 | S12 or S13 or S14 or S15 | Search modes - Boolean/Phrase | 47751 |
| S15 | (MH "Random Assignment") | Search modes - Boolean/Phrase | 27104 |
| S14 | (MH "Double-Blind Studies") | Search modes - Boolean/Phrase | 17138 |
| S13 | (MH "Single-Blind Studies") | Search modes - Boolean/Phrase | 4834 |
| S12 | (MH "Randomized Controlled Trials") | Search modes - Boolean/Phrase | 8205 |
| S11 | S1 and S10 | Search modes - Boolean/Phrase | 465 |
| S10 | S2 or S3 or S4 or S5 or S6 or S7 or S8 or S9 | Search modes - Boolean/Phrase | 122594 |
| S9 | TX dairy OR milk OR cream Or cheese OR butter | Search modes - Boolean/Phrase | 33567 |
| S8 | (MH "Dairy Products+") | Search modes - Boolean/Phrase | 2989 |
| S7 | (MH "Dietary Proteins+") | Search modes - Boolean/Phrase | 3917 |
| S6 | (MH "Diet, Low Carbohydrate") | Search modes - Boolean/Phrase | 266 |
| S5 | (MH "Diet, Fat-Restricted") | Search modes - Boolean/Phrase | 1304 |
| S4 | (MH "Restricted Diet+") | Search modes - Boolean/Phrase | 5270 |
| S3 | (MH "Diet, Sodium-Restricted") | Search modes - Boolean/Phrase | 593 |
| S2 | (MH "Alternative Therapies+") | Search modes - Boolean/Phrase | 84028 |
| S1 | TX "Otitis Media with Effusion" OR "otitis media" OR "middle ear secretion" OR "Ear, Middle/secretion" OR "glue ear" OR middle ear effusion* OR OME OR SOM OR (otitis AND ear) OR (otitis AND ears) OR "nonsuppurative otitis" OR "serous otitis" OR "secretory otitis" OR "adhesive otitis" OR "exudative otitis" OR (mucoid AND otitis) OR (mucous AND otitis) OR (sero-muco* AND otitis) OR (sero AND otitis) OR (sero AND muco*) OR (otitis AND serosa) OR (mucoid AND middle AND ear*) OR (mucous AND middle AN ... | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | 3118 |
Embase: Update
Search August 13, 2012
| No. | Query | Results |
|---|---|---|
| #1 | 'otitis media with effusion'/exp OR 'otitis media with effusion' OR 'otitis media'/exp OR 'otitis media' OR 'middle ear secretion' OR 'ear, middle/secretion' OR 'glue ear'/exp OR 'glue ear' OR middle AND ('ear'/exp OR ear) AND effusion* OR ome OR som OR ('otitis'/exp OR otitis AND ('ear'/exp OR ear)) OR ('otitis'/exp OR otitis AND ears) OR 'nonsuppurative otitis' OR 'serous otitis'/exp OR 'serous otitis' OR 'secretory otitis' OR 'adhesive otitis' OR 'exudative otitis' OR (mucoid AND ('otitis'/exp OR otitis)) OR (mucous AND ('otitis'/exp OR otitis)) OR ('otitis'/exp OR otitis AND ('serosa'/exp OR serosa)) OR (mucoid AND middle AND ('ear'/exp OR ear)) OR (mucous AND middle AND ('ear'/exp OR ear)) AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) | 24,807 |
| #2 | 'steroids'/exp OR steroids OR 'oral'/exp OR oral AND steroid* OR (nasal* AND ('topical'/exp OR topical) AND ('steroid'/exp OR steroid)) OR 'antibacterial agents' OR 'anti-bacterial agents' OR antibiotic* OR autoinflation OR 'ear popper' OR manual AND ('therapy'/exp OR therapy) OR 'pressure'/exp OR pressure AND equalization AND ('tube'/exp OR tube) OR 'adenoidectomy'/exp OR adenoidectomy OR 'middle ear ventilation'/exp OR 'middle ear ventilation' OR tympanostomy OR (middle AND ('ear'/exp OR ear) AND ('tube'/exp OR tube)) OR (middle AND tympanic* AND tube*) OR grommet* OR 'ventilation'/exp OR ventilation AND ('tube'/exp OR tube) OR 'tonsillectomy'/exp OR tonsillectomy OR 'leukotriene antagonists/therapeutic use' OR 'leukotriene antagonists'/exp OR 'acetate'/exp OR acetate OR quinolone* OR 'phosphorylcholine'/exp OR phosphorylcholine OR combined AND modality AND ('therapy'/exp OR therapy) OR 'otologic surgical procedures'/exp OR 'otologic surgical procedures' OR watchful AND waiting OR tubulation AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) | 1916 |
| #3 | #1 AND #2 | 100 |
| #4 | 'myringotomy' OR 'myringotomy'/exp OR myringotomy AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) | 2095 |
| #5 | #3 OR #4 | 2165 |
| #7 | 'alternative medicine'/exp OR 'sodium restriction'/exp OR 'protein restriction'/exp OR 'low carbohydrate diet'/exp OR 'low fat diet'/exp OR 'dairy product'/exp OR dairy OR 'milk'/exp OR 'cream'/exp OR 'cheese'/exp OR 'butter'/exp | 161970 |
| #8 | #1 AND #7 | 140 |
| #9 | #5 OR #8 | 2299 |
| #10 | #9 AND [review]/lim | 330 |
| #11 | #10 AND [humans]/lim AND ([embase]/lim OR [embase classic]/lim) AND [8-12-2011]/sd NOT [13-8-2012]/sd | 23 |
| #12 | 'randomized controlled trial'/exp OR 'single blind procedure'/exp OR 'double blind procedure'/exp OR 'random allocation'/exp | 399,085 |
| #13 | #9 AND #12 | 152 |
| #14 | 'controlled clinical trial'/exp OR 'controlled clinical trial (topic)'/exp | 445,547 |
| #15 | #9 AND #14 | 178 |
| #16 | 'follow up'/exp | 655852 |
| #17 | #9 AND #16 | 209 |
| #18 | 'systematic review'/exp OR 'meta analysis'/exp | 95329 |
| #19 | #9 AND #18 | 44 |
| #20 | 'case control study'/exp OR 'cohort analysis'/exp OR 'epidemiological study' OR 'cross-sectional study'/exp OR 'organizational case study' OR 'crossover procedure'/exp OR 'seroepidemiologic study' OR 'epidemiology'/exp OR 'multicenter study'/exp OR 'multicenter study (topic)'/exp OR 'evaluation research'/exp | 1,979,394 |
| #21 | #9 AND #20 | 324 |
| #22 | #9 AND harms | 1 |
| #23 | #13 OR #15 OR #17 OR #19 OR #21 OR #22 | 641 |
| #24 | #23 AND [humans]/lim AND [8-12-2011]/sd NOT [13-8-2012]/sd | 41 |
| #25 | #11 NOT #24 | 16 |
CINAHLUpdate:
Search Aug 13, 2012
| # | Query | Limiters/Expanders | Results |
|---|---|---|---|
| S47 | S26 or S28 or S30 or S32 or S33 or S44 or S45 | Limiters - Published Date from: 20111201–20121231 Search modes - Boolean/Phrase | 7 |
| S46 | S26 or S28 or S30 or S32 or S33 or S44 or S45 | Search modes - Boolean/Phrase | 354 |
| S45 | S17 AND harms | Search modes - Boolean/Phrase | 2 |
| S44 | S17 and S43 | Search modes - Boolean/Phrase | 255 |
| S43 | S33 or S34 or S35 or S36 or S37 or S38 or S39 or S40 or S41 or S42 | Search modes - Boolean/Phrase | 243768 |
| S42 | (MH "Evaluation Research+") | Search modes - Boolean/Phrase | 16705 |
| S41 | (MH "Multicenter Studies") | Search modes - Boolean/Phrase | 5959 |
| S40 | (MH "Seroprevalence Studies") | Search modes - Boolean/Phrase | 307 |
| S39 | (MH "Crossover Design") | Search modes - Boolean/Phrase | 7226 |
| S38 | "organizational case studies" | Search modes - Boolean/Phrase | 3 |
| S37 | (MH "Cross Sectional Studies") | Search modes - Boolean/Phrase | 49996 |
| S36 | (MH "Epidemiological Research") | Search modes - Boolean/Phrase | 18031 |
| S35 | (MH "Prospective Studies+") | Search modes - Boolean/Phrase | 133542 |
| S34 | (MH "Case Control Studies+") | Search modes - Boolean/Phrase | 26734 |
| S33 | S17 AND (MH "Observational Methods+") | Search modes - Boolean/Phrase | 4 |
| S32 | S17 and S31 | Search modes - Boolean/Phrase | 21 |
| S31 | (MH "Meta Analysis") | Search modes - Boolean/Phrase | 11747 |
| S30 | S17 and S29 | Search modes - Boolean/Phrase | 10 |
| S29 | (MH "Systematic Review") | Search modes - Boolean/Phrase | 10937 |
| S28 | S17 and S27 | Search modes - Boolean/Phrase | 132 |
| S27 | "controlled clinical trial" OR (MH "Clinical Trials+") | Search modes - Boolean/Phrase | 106932 |
| S26 | S17 and S25 | Search modes - Boolean/Phrase | 77 |
| S25 | S21 or S22 or S23 or S24 | Search modes - Boolean/Phrase | 50882 |
| S24 | (MH "Random Assignment") | Search modes - Boolean/Phrase | 27917 |
| S23 | (MH "Double-Blind Studies") | Search modes - Boolean/Phrase | 17853 |
| S22 | (MH "Single-Blind Studies") | Search modes - Boolean/Phrase | 5117 |
| S21 | (MH "Randomized Controlled Trials") | Search modes - Boolean/Phrase | 10402 |
| S20 | S17 and S18 | Limiters - Published Date from: 20111201–20121231 Search modes - Boolean/Phrase | 0 |
| S19 | S17 and S18 | Search modes - Boolean/Phrase | 15 |
| S18 | (MH "Literature Review+") | Search modes - Boolean/Phrase | 13858 |
| S17 | S16 | Limiters - Human Search modes - Boolean/Phrase | 618 |
| S16 | S5 or S15 | Search modes - Boolean/Phrase | 1543 |
| S15 | S1 and S14 | Search modes - Boolean/Phrase | 155 |
| S14 | S6 or S7 or S8 or S9 or S10 or S11 or S12 or S13 | Search modes - Boolean/Phrase | 108145 |
| S13 | TX dairy OR milk OR cream Or cheese OR butter | Search modes - Boolean/Phrase | 14534 |
| S12 | (MH "Dairy Products+") | Search modes - Boolean/Phrase | 3124 |
| S11 | (MH "Dietary Proteins+") | Search modes - Boolean/Phrase | 4086 |
| S10 | (MH "Diet, Low Carbohydrate") | Search modes - Boolean/Phrase | 289 |
| S9 | (MH "Diet, Fat-Restricted") | Search modes - Boolean/Phrase | 1337 |
| S8 | (MH "Restricted Diet+") | Search modes - Boolean/Phrase | 5458 |
| S7 | (MH "Diet, Sodium-Restricted") | Search modes - Boolean/Phrase | 620 |
| S6 | (MH "Alternative Therapies+") | Search modes - Boolean/Phrase | 87068 |
| S5 | S3 OR S4 | Search modes - Boolean/Phrase | 1472 |
| S4 | TX myringotomy | Search modes - Boolean/Phrase | 306 |
| S3 | S1 AND S2 | Search modes - Boolean/Phrase | 1262 |
| S2 | TX "Histamine Antagonists" OR antihistamine* OR "Steroids" OR oral steroid* OR (nasal* AND topical steroid*) OR "Anti-Bacterial Agents" OR antibiotic* OR complementary medicine* OR alternative medicine* OR complementary therap* OR alternative therap* OR "ear popper" OR manual therap* OR pressure equalization tube* OR adenoidectom* OR "Middle Ear Ventilation" OR tympanostomy OR (middle AND ear*AND tube*) OR (middle AND tympanic* AND tube*) OR grommet* OR ventilation tube* OR tonsillectomy OR "Leukotriene Antagonists/therapeutic use" OR "Leukotriene Antagonists" OR acetate* OR quinolone* OR phosphorylcholine OR combined modality therap* OR "Otologic Surgical Procedures" OR watchful waiting* OR tubulation | Search modes - Boolean/Phrase | 69123 |
| S1 | TX "Otitis Media with Effusion" OR "otitis media" OR "middle ear secretion" OR "Ear, Middle/secretion" OR "glue ear" OR middle ear effusion* OR OME OR SOM OR (otitis AND ear) OR (otitis AND ears) OR "nonsuppurative otitis" OR "serous otitis" OR "secretory otitis" OR "adhesive otitis" OR "exudative otitis" OR (mucoid AND otitis) OR (mucous AND otitis) OR (sero-muco* AND otitis) OR (sero AND otitis) OR (sero AND muco*) OR (otitis AND serosa) OR (mucoid AND middle AND ear*) OR (mucous AND middle AND ear*) OR (seromuc* AND middle AND ear*) | Search modes - Boolean/Phrase | 3498 |
Cochrane Library Update: August 13, 2012
Current Search History
| ID | Search | Hits |
|---|---|---|
| #1 | "Otitis Media with Effusion" OR "otitis media" OR "middle ear secretion" OR "Ear, Middle/secretion" OR "glue ear" OR middle ear effusion* OR OME OR SOM OR (otitis AND ear) OR (otitis AND ears) OR "nonsuppurative otitis" OR "serous otitis" OR "secretory otitis" OR "adhesive otitis" OR "exudative otitis" OR (mucoid AND otitis) OR (mucous AND otitis) OR (sero-muco* AND otitis) OR ((sero OR muco) AND otitis) OR (otitis AND serosa) OR (mucoid AND middle AND ear*) OR (mucous AND middle AND ear*) OR (seromuc* AND middle AND ear*) | 2327 |
| #2 | "Steroids" OR oral steroid* OR (nasal* AND topical steroid*) OR "Anti-Bacterial Agents" OR antibiotic* OR "ear popper" OR manual therap* OR pressure equalization tube* OR adenoidectom* OR "Middle Ear Ventilation" OR tympanostomy OR (middle AND ear*AND tube*) OR (middle AND tympanic* AND tube*) OR grommet* OR ventilation tube* OR tonsillectomy OR "Leukotriene Antagonists/therapeutic use" OR "Leukotriene Antagonists" OR acetate* OR quinolone* OR phosphorylcholine OR combined modality therap* OR "Otologic Surgical Procedures" OR watchful waiting* OR tabulation OR autoinflation | 52955 |
| #3 | MeSH descriptor Complementary Therapies explode all trees | 11802 |
| #4 | MeSH descriptor Diet, Sodium-Restricted explode all trees | 461 |
| #5 | MeSH descriptor Diet, Protein-Restricted explode all trees | 145 |
| #6 | MeSH descriptor Diet, Fat-Restricted explode all trees | 648 |
| #7 | MeSH descriptor Diet, Carbohydrate-Restricted explode all trees | 131 |
| #8 | MeSH descriptor Dairy Products explode all trees | 2375 |
| #9 | dairy OR milk OR cream OR cheese OR butter | 9329 |
| #10 | (#2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9) | 72917 |
| #11 | (#1 AND #10) | 1142 |
| #12 | (#11 OR myringotomy) | 1243 |
| #13 | Method" OR "Random Allocation" OR "Controlled Clinical Trial" OR "Controlled Clinical Trials as Topic" OR (control* AND trial) | 718613 |
| #14 | (#12 AND #13) | 1225 |
| #15 | ("Case-Control Studies"[MeSH] OR "Cohort Studies"[MeSH] OR "Epidemiologic Studies"[MeSH] OR "Cross-Sectional Studies"[MeSH] OR "Organizational Case Studies"[MeSH] OR "Cross-Over Studies"[MeSH] OR "Follow-Up Studies"[MeSH] OR "Seroepidemiologic Studies"[MeSH] OR "Multicenter Study"[Publication Type] OR "Multicenter Studies as Topic"[MeSH] OR "Evaluation Studies"[Publication Type] OR "Evaluation Studies as Topic"[MeSH]) | 125753 |
| #16 | (#12 AND #15) | 372 |
| #17 | (#12), from 2011 to 2012 | 139 |
| #18 | (#14 OR #16 OR #17) | 1226 |
| #19 | (#18), from 2011 to 2012 | 139 |
PubMed Update: August 13, 2012
| Search | Query | Items found |
|---|---|---|
| #1 | Search "Otitis Media with Effusion"[Mesh] | 4594 |
| #2 | Search "Ear, Middle/secretion"[Mesh] | 101 |
| #3 | Search "glue ear"[tiab] | 252 |
| #4 | Search "otitis media"[tiab] | 15500 |
| #5 | Search middle ear effusion* | 1633 |
| #6 | Search (OME[tiab] OR SOM[tiab]) AND (otitis[tiab] OR ear*[tiab]) | 1507 |
| #7 | Search "nonsuppurative otitis"[tiab] | 0 |
| #8 | Search "serous otitis"[tiab] | 616 |
| #9 | Search "secretory otitis"[tiab] | 945 |
| #10 | Search "adhesive otitis"[tiab] | 168 |
| #11 | Search "exudative otitis"[tiab] | 92 |
| #12 | Search (mucoid*[tiab] AND otitis[tiab]) OR (mucous[tiab] AND otitis[tiab]) OR (sero-muco*[tiab] AND otitis[tiab]) OR (sero[tiab] OR muco[tiab] AND otitis[tiab]) OR (otitis[tiab] AND serosa[tiab]) | 420 |
| #13 | Search (mucoid*[tiab] AND middle[tiab] AND ear*[tiab]) OR (mucous[tiab] AND middle[tiab] AND ear*[tiab]) OR (seromuc*[tiab] AND middle[tiab] AND ear*[tiab]) | 469 |
| #14 | Search #1 or #2 or #3 or #4 or #5 or #6 or #7 or #8 or #9 or #10 or #11 or #12 or #13 | 17740 |
| #15 | Search "Steroids"[Mesh] OR oral steroid* | 665533 |
| #16 | Search nasal*[tiab] AND (topical steroid*[tiab]) | 226 |
| #17 | Search "Anti-Bacterial Agents"[Mesh] OR antibiotic* | 379785 |
| #18 | Search "ear popper"[tiab] OR manual therap*[tiab] | 1042 |
| #19 | Search autoinflation[tiab] | 50 |
| #20 | Search pressure equalization tube*[tiab] | 58 |
| #21 | Search "Adenoidectomy"[Mesh] OR adenoidectom*[tiab] | 3977 |
| #22 | Search "Middle Ear Ventilation"[Mesh] OR tympanostomy[tiab] OR ((middle[tiab] AND (ear*[tiab] OR tympanic[tiab])) AND tube*[tiab]) | 4226 |
| #23 | Search grommet*[tiab] | 448 |
| #24 | Search ventilation tube*[tiab] | 807 |
| #25 | Search "Tonsillectomy"[Mesh] OR tonsillectomy[tiab] | 8769 |
| #26 | Search "Leukotriene Antagonists/therapeutic use"[Mesh] OR "Leukotriene Antagonists" [Pharmacological Action] | 4122 |
| #27 | Search "Acetates/therapeutic use"[Mesh] | 2860 |
| #28 | Search "Quinolines/therapeutic use"[Mesh] | 36041 |
| #29 | Search "Combined Modality Therapy"[Mesh] OR combined modality therap*[tiab] | 183840 |
| #30 | Search myringotomy[tiab] | 1085 |
| #31 | Search "Otologic Surgical Procedures"[Mesh] | 13612 |
| #32 | Search "Phosphorylcholine/administration and dosage"[Mesh] OR "Phosphorylcholine/therapeutic use"[Mesh] | 438 |
| #33 | Search "Watchful Waiting"[Mesh] OR watchful waiting*[tiab] | 1729 |
| #34 | Search tubulation[tiab] | 272 |
| #35 | Search "Complementary Therapies"[Mesh] | 159794 |
| #36 | Search "Diet, Sodium-Restricted"[Mesh] | 5207 |
| #37 | Search "Diet, Protein-Restricted"[Mesh] | 1671 |
| #38 | Search "Diet, Carbohydrate-Restricted"[Mesh] | 600 |
| #39 | Search "Diet, Fat-Restricted"[Mesh] | 2439 |
| #40 | Search "Dairy Products"[Mesh] | 67792 |
| #41 | Search dairy OR milk OR cream Or cheese OR butter | 134103 |
| #42 | Search #15 or #16 or #17 or #18 or #19 or #20 or #21 or #22 or #23 or #24 or #25 or #26 or #27 or #28 or #29 or #31 or #32 or #33 or #34 or #35 or #36 or #37 or #38 or #39 or #40 or #41 | 1540392 |
| #43 | Search #14 and #42 | 7300 |
| #44 | Search #43 or #30 | 7858 |
| #45 | Search #43 or #30 Filters: Humans | 6955 |
| #46 | Search "Randomized Controlled Trial"[Publication Type] OR "Single-Blind Method"[MeSH] OR "Double-Blind Method"[MeSH] OR "Random Allocation"[MeSH] | 412868 |
| #47 | Search #45 and #46 | 617 |
| #48 | Search #43 or #30 Filters: Humans; Controlled Clinical Trial | 72 |
| #49 | Search #45 AND "Controlled Clinical Trials as Topic"[Mesh] | 142 |
| #50 | Search #47 or #48 or #49 | 786 |
| #51 | Search #45 AND systematic[sb] | 273 |
| #52 | Search #43 or #30 Filters: Humans; Meta-Analysis | 58 |
| #53 | Search #51 or #52 | 273 |
| #54 | Search ("Case-Control Studies"[MeSH] OR "Cohort Studies"[MeSH] OR "Epidemiologic Studies"[MeSH] OR "Cross-Sectional Studies"[MeSH] OR "Organizational Case Studies"[MeSH] OR "Cross-Over Studies"[MeSH] OR "Follow-Up Studies"[MeSH] OR "Seroepidemiologic Studies"[MeSH] OR "Multicenter Study"[Publication Type] OR “Multicenter Studies as Topic”[MeSH] OR "Evaluation Studies"[Publication Type] OR “Evaluation Studies as Topic”[MeSH]) | 2420779 |
| #55 | Search #45 and #54 | 2719 |
| #56 | Search #45 AND harms | 5 |
| #57 | Search #50 or #53 or #55 or #56 | 3072 |
| #58 | Search #57 AND (2011/06/12:2012/13/08[edat]) | 72 |
| #59 | Search #43 or #30 Filters: Humans; Review | 1028 |
| #60 | Search #59 AND (2011/06/12:2012/13/08[edat]) | 15 |
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