The Agency for Healthcare Research and Quality (AHRQ), through its Evidence-based Practice Centers (EPCs), sponsors the development of evidence reports and technology assessments to assist public- and private-sector organizations in their efforts to improve the quality of health care in the United States.

The Patient-Centered Outcomes Research Institute (PCORI) was established to fund research that can help patients and those who care for them make better informed decisions about the health care choices they face every day. PCORI partnered with AHRQ to help fulfill PCORI’s authorizing mandate to engage in evidence synthesis and make information from comparative effectiveness research more available to patients and providers. PCORI identifies topics for review based on broad stakeholder interest. After identifying specific topics, multistakeholder virtual workshops are held by PCORI to inform the individual research protocols.

The reports and assessments provide organizations, patients, clinicians, and caregivers with comprehensive, evidence-based information on common medical conditions and new health care technologies and strategies. They also identify research gaps in the selected scientific area, identify methodological and scientific weaknesses, suggest research needs, and move the field forward through an unbiased, evidence-based assessment of the available literature. The EPCs systematically review the relevant scientific literature on topics assigned to them by AHRQ and conduct additional analyses when appropriate prior to developing their reports and assessments.

To bring the broadest range of experts into the development of evidence reports and health technology assessments, AHRQ encourages the EPCs to form partnerships and enter into collaborations with other medical and research organizations. The EPCs work with these partner organizations to ensure that the evidence reports and technology assessments they produce will become building blocks for health care quality improvement projects throughout the Nation. The reports undergo peer review and public comment prior to their release as a final report.

AHRQ expects that the EPC evidence reports and technology assessments, when appropriate, will inform patients and caregivers, individual health plans, providers, and purchasers as well as the health care system as a whole by providing important information to help improve health care quality.

If you have comments on this evidence report, they may be sent by mail to the Task Order Officer: Aysegul Gozu, M.D., M.P.H., Agency for Healthcare Research and Quality, 5600 Fishers Lane, Rockville, MD 20857, or by email to vog.shh.qrha@cpe.

• Gopal Khanna, M.B.A.
  Director
  Agency for Healthcare Research and Quality
• Joe V. Selby, M.D., M.P.H.
  Executive Director
  PCORI
• Arlene S. Bierman, M.D., M.S.
  Director
  Center for Evidence and Practice Improvement
  Agency for Healthcare Research and Quality
• Diane E. Bild, M.D., M.P.H.
  Acting Chief Science Officer
  PCORI