Funnel Plot of High-THC Ratio Studies Included in Meta-Analysis for Pain Severity

Marian S. McDonagh; Jesse Wagner; Azrah Y. Ahmed; Rongwei Fu; Benjamin Morasco; Devan Kansagara; Roger Chou

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McDonagh MS, Wagner J, Ahmed AY, et al. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Oct. (Comparative Effectiveness Review, No. 250.)

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Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain [Internet].

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Appendix IFunnel Plot of High-THC Ratio Studies Included in Meta-Analysis for Pain Severity

This figure is a funnel plot of 8 trials included in the meta-analysis assessing effects on pain severity for high-THC ratio products versus placebo. There are circular symbols representing individual studies, plotted on an x-axis of group differences (from -4 to 1) and a y-axis of the standard error of the group differences (from 1.5 to 0). The test for small study effects was statistically significant (Egger test, p value=0.006).

Figure I-1Funnel plot of eight trials of pain severity for high-THC ratio products versus placebo

Abbreviations: Groupdiff = group difference; SE = standard error.

Bookshelf ID: NBK575751

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McDonagh MS, Wagner J, Ahmed AY, et al. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2021 Oct. (Comparative Effectiveness Review, No. 250.) Appendix I, Funnel Plot of High-THC Ratio Studies Included in Meta-Analysis for Pain Severity.
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