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McPheeters M, O’Connor EA, Riley S, et al. Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2023 Nov. (Comparative Effectiveness Review, No. 262.)

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Pharmacotherapy for Adults With Alcohol Use Disorder in Outpatient Settings: Systematic Review [Internet].

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6Abbreviations and Acronyms

ACA

acamprosate

AE

adverse event

ALD

alcoholic liver disease

ASI

Addiction Severity Index

AUD

alcohol use disorder

AUDIT

Alcohol Use Disorders Identification Test

BAC

baclofen

BBCET

brief behavioral compliance enhancement treatment

BPD

bipolar disorder

BRENDA

BRENDA is an acronym based on the components of the intervention: (B)iopsychosocial evaluation, (R)eport to the patient on assessment, (E)mpathic understanding of the patient’s situation, (N)eeds collaboratively identified by the patient and treatment provider, (D)irect advice to the patient on how to meet those needs, (A)ssess reaction of the patient to advice and adjust as necessary for best care

BST

broad spectrum treatment

CB

cognitive behavioral

CBCST

cognitive behavioral coping skills therapy

CBI

combined behavioral intervention

CBT

cognitive behavioral therapy

CI

confidence interval

CM

contingency management

CND

cannot determine

COMBINE

Combined Pharmacotherapies and Behavioral Intervention

CS

coping skills

DBRCT

double blind randomized control trial

DC

drug counseling

DD

drinking days

DIS

disulfiram

DrInC

Drinker Inventory of Consequences

DSM-IV

Diagnostic and Statistical Manual of Mental Disorders version 4

FDA

Food and Drug Administration

GAB

gabapentin

GABA

gamma-aminobutyric acid

GAD

generalized anxiety disorder

GHB

γ-Hydroxybuteric acid

GP

general practitioner

HaRT-A

Harm Reduction Treatment for Alcohol

HDD

heavy drinking days

HIV

human immunodeficiency virus

IBT

integrative behavior therapy

IE

insufficient evidence

inj

injectable

ITT

intent to treat

KQ

Key Question

LOCF

last observation carried forward

MATCH

Matching Alcoholism Treatments to Client Heterogeneity

MBCST

modified behavioral self-control therapy

MCV

mean corpuscular volume

MDD

major depressive disorder

med

medium

MedDRA

Mental Dictionary for Regulatory Activities

MET

motivational enhancement therapy

mg

milligrams

MIRECC

Mental Illness Research, Education and Clinical Center

MM

medical management

N

sample size

NA

not applicable

NE

no effect

NNT

number needed to treat

No.

number

NOS

not otherwise specified

NR

no reported

NSD

no significant difference

NTX

naltrexone

OCD

obsessive-compulsive disorder

OCDS

Obsessive Compulsive Disorder Drinking Scale

OLRCT

open-label randomized controlled trial

OND

ondansetron

PLA

placebo

PRA

prazosin

PTSD

post-traumatic stress disorder

PUFA

polyunsaturated fatty acid

Q-LES-Q

Quality of Life Enjoyment and Satisfaction Questionnaire

QoL

quality of life

RCT

randomized controlled trial

RIB

riboflavin

RoB

risk of bias

RPT

relapse prevention therapy

RR

risk ratio

Rx

Prescription

SADD

Short Alcohol Dependence Data

SAFTEE

Systematic Assessment for Treatment Emergent Events

SBRCT

single-blind randomized controlled trial

SD

standard deviation

SE

standard error

SERT

sertraline

SF-12

12-item Short-Form Health Survey

SF-36

36-Item Short Form Survey

SOE

strength of evidence

ST

supportive therapy

TAU

treatment as usual

TBI

traumatic brain injury

TLFB

timeline followback method

TOP

Topiramate

UK

United Kingdom

Unc

unclear

US

United States

VA

Veterans Affairs

VACS

Veterans Affairs Cooperative Study

VAMC

Veterans Administration Medical Center

VAR

varenicline

vs.

versus

WHOQOL

World Health Organization Quality of Life

WMD

weighted mean difference

XR

extended release

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