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Skelly AC, Chang E, Bordley J, et al. Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2023 Aug. (Comparative Effectiveness Review, No. 265.)

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Radiation Therapy for Metastatic Bone Disease: Effectiveness and Harms [Internet].

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6Abbreviations and Acronyms

2DCRT

two-dimensional conformal radiation therapy

3DCRT

three-dimensional conformal radiation therapy

AHRQ

Agency for Healthcare Research and Quality

ANCOVA

analysis of covariance

ARD

absolute risk difference

ASTRO

American Society for Radiation Oncology

BPI

Brief Pain Inventory

BPTWG

Bone Pain Trial Working Group

CI

confidence interval

CPG

Clinical Practice Guideline

EBRT

external beam radiation therapy

ECOG

Eastern Cooperative Oncology Group

EORTC

European Organisation for Research and Treatment of Cancer

EORTC-QLQ-BM22

EORTC Quality of Life Group Bone Metastases Module

EORTC QLQ-C15-PAL

EORTC Quality of Life Questionnaire–Core 15 Palliative

EORTC QLQ-C30

EORTC Quality of Life Questionnaire

HBI

hemibody irradiation

HDMF

higher total dose multiple fraction

HDSF

higher total dose single fraction

HR

hazard ratio

IMRT

intensity modulated radiation therapy

IQR

interquartile range

KPS

Karnofsky Performance Scale

KQ

Key Question

LDMF

lower total dose multiple fraction

LDSF

lower total dose single fraction

MBD

metastatic bone disease

MCID

minimal clinically important difference

MCS

Mental Component Score

MD

mean difference

MF

multiple fraction

MFRT

multiple fraction radiation treatment

MPI

multidimensional pain inventory

MQOL

McGill Quality of Life Questionnaire

MSCC

metastatic spinal cord compression

NA

not applicable

NR

not reported

NRS

numerical rating scale

NRSI

nonrandomized study of interventions

NSAID

nonsteroidal anti-inflammatory drug

QOL

quality of life

PL

profile likelihood

OR

odds ratio

RCT

randomized controlled trial

RR

risk ratio

RT

radiation therapy

SCC

spinal cord compression

SBRT

stereotactic body radiation therapy

SD

standard deviation

SF

single fraction

SF-36

Short-Form 36 Questionnaire

SFRT

single fraction radiation treatment

SINS

Spinal Instability in Neoplasia Score

SRE

skeletal-related event

VCF

vertebral compression fracture

VAS

visual analog scale

WHO

World Health Organization

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