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Treadwell J, Tipton K, Oyesanmi O, et al. Surgical Options for Inguinal Hernia: Comparative Effectiveness Review [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2012 Aug. (Comparative Effectiveness Reviews, No. 70.)

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

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Surgical Options for Inguinal Hernia: Comparative Effectiveness Review [Internet].

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Appendix BExcluded Studies

Table 1Excluded studies

StudyReason for Exclusion
Aasbo et al., 20021Anesthesia
Aasvang et al., 20052Review
Aeberhard et al., 19993Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Agarwal et al., 20104Nonrandomized study that did not attempt to control for possible baseline differences between groups
Agresta et al., 20095Did not address any Key Question
Aigner et al., 20116Abstract only
Aitola et al., 19987Did not focus sufficiently on a patient population of interest; 18% (9/49) had recurrent hernia
Akbulut et al., 20038Did not report any outcomes of interest
Akcaboy et al., 20099Anesthesia
Akhtar et al., 199810Did not address any Key Question
Akolekar et al., 200811Nonrandomized study that did not attempt to control for possible baseline differences between groups
Alani et al., 200612Nonrandomized study that did not attempt to control for possible baseline differences between groups
Albright et al., 201113Nonconcurrent enrollment
Alfieri et al., 200614Neurectomy
Altinli et al., 201115Abstract only
Amato et al., 200916Review
Amid et al., 199417Clinical comment
Amid et al., 199618Did not address any Key Question
Anadol et al., 201119Nonrandomized study that did not attempt to control for selection bias
Anderson et al., 198020Antibiotics
Andrew et al., 199421Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Antao et al., 200422Nonconcurrent enrollment
Arregui et al., 200523Case series
Arvidsson et al., 200024Narrative review
Arvidsson et al., 200525Did not address any Key Question
Atkinson et al., 200426Did not address any Key Question
Aufenacker et al., 200427Antibiotics
Awad et al., 200728Nonconcurrent enrollment
Aydede et al., 200329Did not report any outcomes of interest
Aytac et al., 200430Did not address any Key Question
Babineau et al., 200431Surgical experience information not specific to laparoscopic hernia repair
Baca et al., 199532Nonrandomized study that did not attempt to control for possible baseline differences between groups
Baca et al., 200033Unable to obtain
Balakrishnan et al., 200834Case series
Ballantyne et al., 200135Case series
Baltazar et al., 197636Did not address any Key Question
Bar-Dayan et al., 200437Anesthesia
Baris et al., 200338Anesthesia
Barkun et al., 199539Did not address any Key Question
Barkun et al., 199940Only half of the open repairs used a mesh; data on these repairs was not reported separately
Barrat et al., 200341Did report any post-treatment outcomes
Barth et al., 199842Did not address any Key Question
Batorfi et al., 199543Did not report any outcomes comparing procedures
Bay-Nielsen et al., 199944Anesthesia
Beddy et al., 200645Did not report any outcomes of interest
Beets et al., 199746Did not address any Key Question
Bell et al., 200347Nonrandomized study that did not attempt to control for possible baseline differences between groups
Bemdsen et al., 200248Did not address any Key Question
Bencini et al., 200449Incisional hernia
Ben-David et al., 199550Anesthesia
Ben-Haim et al., 200251Incisional hernia
Benizri et al., 200652Nonconcurrent enrollment
Berndsen et al., 200253Did not address any Key Question
Berndsen et al., 200254Did not address any Key Question
Berndsen et al., 200755Did not address any Key Question
Bessell et al., 199656Did not address any Key Question
Bhattacharya et al., 201057Anesthesia
Biemans et al., 199858Did not address any Key Question
Bilgin et al., 199759Abstract only
Billingham et al., 201060Review
Birk et al., 199861Case series
Bisgaard et al., 201062Did not address any Key Question
Bittner et al., 200563Review
Bittner et al., 201064Case series
Blaser et al., 201165Abstract only
Borenstein et al., 200566Did not address any Key Question
Bozuk et al., 200367Nonrandomized study that did not attempt to control for possible baseline differences between groups
Brandt et al., 200868Background
Bright et al., 201069Nonrandomized study that did not attempt to control for possible baseline differences between groups
Bringman et al., 200170Did not address any Key Question
Bringman et al., 200171Did not address any Key Question
Brooks et al., 199472Nonrandomized study that did not attempt to control for possible baseline differences between groups
Brunner et al., 201173Abstract only
Burney et al., 200474Anesthesia
Cahil et al., 198975Did not address any Key Question
Callesen et al., 199876Did not address any Key Question
Callesen et al., 199877Case series
Callesen et al., 199978Did not address any Key Question
Callesen et al., 199979Confounding by indication
Calliskan et al., 201080Neurectomy
Campanelli et al., 200881Trial protocol
Canonico et al., 200382Review
Casati et al., 200483Anesthesia
Castoro et al., 199684Did not address any Key Question
Ceccarelli et al., 200885Nonrandomized study that did not attempt to control for possible baseline differences between groups
Celdran et al., 200486Antibiotics
Cesana et al., 201187Abstract only
Champault et al., 200788Nonrandomized study that did not attempt to control for possible baseline differences between groups
Champault et al., 201189Case series
Chan et al., 200490Case series
Chan et al., 200491Did not address any Key Question
Chan et al., 201192Did not address any Key Question
Chawla et al., 200593Novel technique
Cheek et al., 199894Review
Chowbey et al., 200395Case series
Chu et al., 199396Case series
Chung et al., 199997Review
Cingi et al., 200598Did not address any Key Question
Cocks et al., 199899Nonconcurrent enrollment
Cohen et al., 1998100Nonrandomized study that did not attempt to control for possible baseline differences between groups
Cohen et al., 1998101Case series
Collaborative group et al., 2000102Review
Collage et al., 2010103Clinical comment
Connelly et al., 1997104Anesthesia
Conroy et al., 1993105Anesthesia
Corbitt et al., 1991106Case series
Cornell et al., 1994107Did not address any Key Question
Courtney et al., 2002108Did not address any Key Question
Cox et al., 2011109Abstract only
Craven et al., 2009110Review
Cunningham et al., 1996111Did not address any Key Question
Czudek et al., 2009112Case series
Dallas et al., 2011113Abstract only
Damamme et al., 1998114Not English
Daniel et al., 1997115Case series
Danielsson et al., 1999116Did not address any Key Question
Dasari et al., 2009117Retrospective questionnaire data relying on memory
Davenport et al., 2003118Clinical comment
Davis et al., 1994119Anesthesia
de Jonge et al., 2008120Review
de Sa Ribeiro et al., 2010121Case series
de Vries et al., 2007122Did not address any Key Question
Decker et al., 1998123Did not address any Key Question
Dedemadi et al., 2010124Review
Demiraran et al., 2006125Anesthesia
Demirbas et al., 2003126Nonrandomized study that did not attempt to control for possible baseline differences between groups
DeTurris et al., 2002127Review
Deysine et al., 1991128Did not address any Key Question
Deysine et al., 2006129Did not address any Key Question
Di Filippo et al., 2006130Anesthesia
Di Vita et al., 2000131Did not address any Key Question
Di Vita et al., 2001132Did not address any Key Question
Di Vita et al., 2005133Did not address any Key Question
Dick et al., 1996134Case series
Dickinson et al., 2008135Nonrandomized study that did not attempt to control for possible baseline differences between groups
Dierking et al., 1992136Anesthesia
Dilek et al., 2005137Did not report any outcomes of interest
Dion et al., 1996138Data were considering for the surgical experience question, however of the 158 patients undergoing laparoscopic repair, data related to surgical experience were only reported for 118 of them, and the reason for this selection was not reported.
Dorflinger et al., 1984139Did not address any Key Question
DuBois et al., 1997140Case series
Dueholm et al., 1989141Anesthesia
Duff et al., 2007142Nonrandomized study that did not attempt to control for possible baseline differences between groups
Edelman et al., 2001143Did not report any outcomes of interest
Edelman et al., 2002144Nonrandomized study that did not attempt to control for possible baseline differences between groups
Edelman et al., 2008145Nonrandomized study that did not attempt to control for possible baseline differences between groups
Eker et al., 2011146Abstract only
Eller et al., 2002147Case series
El-Radaideh et al., 2006148Anesthesia
emedicine et al., 2010149Background
Eno et al., 2000150Did not report whether mesh was used for open hernia repair
epocrates et al., 2010151Background
Erhan et al., 2008152Nonrandomized study that did not attempt to control for possible baseline differences between groups
Erichsen et al., 1995153Anesthesia
Erol et al., 2009154Anesthesia
Ersin et al., 2006155Did not report any outcomes of interest
EU et al., 2000156Review
EU Hernia Trialists Collaboration et al., 2002157Review
Evans et al., 1973158Antibiotics
Evans et al., 2002159Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Fallas et al., 1994160Nonrandomized study that did not attempt to control for possible baseline differences between groups
Farooq et al., 2007161Unable to obtain
Feliu et al., 2004162Nonrandomized study that did not attempt to control for possible baseline differences between groups
Feliu et al., 2004163Nonrandomized study that did not attempt to control for possible baseline differences between groups
Felix et al., 1995164Nonconcurrent enrollment
Felix et al., 1995165Did not report any outcomes comparing procedures
Felix et al., 1996166Did not report any outcomes comparing procedures
Felix et al., 1997167Case series
Felix et al., 1999168Nonrandomized study that did not attempt to control for possible baseline differences between groups
Fell et al., 1988169Anesthesia
Ferzli et al., 2004170Did not address any Key Question
Ferzli et al., 2006171Case series
Fielding et al., 1995172Case series
Filipi et al., 1996173Did not focus sufficiently on a patient population of interest; 18% (9/53) had recurrent hernia.
Fine et al., 2006174Case series
Fischer et al., 1999175Narrative review bilateral
Fischer et al., 2000176Anesthesia
Fitzgibbone et al., 1995177Nonrandomized study that did not attempt to control for possible baseline differences between groups
Fleming et al., 2001178Did not address any Key Question
Forte et al., 2003179Case series
Friis et al., 1996180Did not address any Key Question
Fuenfer et al., 1996181Case series
Fujita et al., 2004182Confounding by indication
Gao et al., 2010183Review
Garg et al., 2009184Nonrandomized study that did not attempt to control for possible baseline differences between groups
Gholghesaei et al., 2005185Review
Gianetta et al., 2000186Did not address any Key Question
Gilbert et al., 2004187Did not address any Key Question
Gilbert et al., 2006188Combined narrative review and original data; original data comparing surgeons was not specific to laparoscopy
Gillion et al., 1999189Nonrandomized study that did not attempt to control for possible baseline differences between groups
Girao et al., unpublished190Did not address any Key Question
Go et al., 1998191Narrative review
Godfrey et al., 1981192Anesthesia
Gokcora et al., 1996193Did not address any Key Question
Golash et al., 2011194Abstract only
Gontarz et al., 1998195Abstract only
Gonullu et al., 2002196Anesthesia
Goodwin et al., 1995197Nonrandomized study that did not attempt to control for possible baseline differences between groups
Gramke et al., 2006198Anesthesia
Grant et al., 2002199Review
Grant et al., 2002200Review
Grossmann et al., 1995201Case series
Grunwaldt et al., 2005202Narrative review
Gultekin et al., 2007203Anesthesia
Gunes et al., 2004204Anesthesia
Gupta et al., 2003205Anesthesia
Gurleyik et al., 1998206Did not address any Key Question
Gursoy et al., 1997207Case series
Guzman-Valdivia et al., 2003208Did not address any Key Question
Hadzic et al., 2006209Anesthesia
Hair et al., 2000210Data for different procedures not reported separately
Haitian et al., 2009211TEP procedure did not use a mesh, thus the study did not address any Key Question
Hakeem et al., 2010212Review protocol
Halm et al., 2005213Nonrandomized study that did not attempt to control for possible baseline differences between groups
Harjai et al., 2007214Did not address any Key Question
Hatch et al., 1994215Case series
Hawasli et al., 2002216Did not address any Key Question
Hay et al., 1995217Did not address any Key Question
Hernandez-Granados et al., 2000218Did not address any Key Question
Hetzer et al., 1993219Did not address any Key Question
Hidalgo et al., 2005220Nonrandomized study that did not attempt to control for possible baseline differences between groups
Hilgert et al., 1999221Did not address any Key Question
Himpens et al., 1993222Nonrandomized study that did not attempt to control for possible baseline differences between groups
Himpens et al., 1997223TEP procedure did not use a mesh, thus the study did not address any Key Question
Hindmarsh et al., 2003224Did not report whether mesh was used for open hernia repair
Holcomb et al., 1996225Case series
Hon et al., 2009226Anesthesia
Hong et al., 2010227Anesthesia
Horgan et al., 1996228Animal research
Horharin et al., 2006229Nonrandomized study that did not attempt to control for possible baseline differences between groups
Horstmann et al., 2006230Nonconcurrent enrollment
Horton et al., 1993231Case series
Horzia et al., 2006232Did not address any Key Question
Huang et al., 2005233Nonrandomized study that did not attempt to control for possible baseline differences between groups
Hussein et al., 1998234Case series
Ismail et al., 2009235Nonrandomized study that did not attempt to control for possible baseline differences between groups
Jacobs et al., 2004236Background
Jain et al., 2008237Antibiotics
Jain et al., 2009238Nonrandomized study that did not attempt to control for possible baseline differences between groups
Jani et al., 2005239Did not address any Key Question
Jansson et al., 2000240Did not address any Key Question
Janu et al., 1997241Did not address any Key Question
Janu et al., 1998242Did not address any Key Question
Jarhult et al., 1999243Nonconcurrent enrollment
Jeans et al., 2007244Narrative review
Jenkins et al., 2008245Background
Jenkinson et al., 1995246Did not address any Key Question
Jess et al., 2000247Antibiotics
Joshi et al., 1999248Anesthesia
Juang et al., 2011249Case series
Juul et al., 1999250Did not address any Key Question
Kald et al., 1997251Did not address any Key Question
Kald et al., 1997252Nonconcurrent enrollment
Kalman et al., 1995253Anesthesia
Karakayali et al., 2007254Did not address any Key Question
Kark et al., 1995255Case series
Karthikesalingam et al., 2010256Review
Kaufman et al., 1996257Case series
Kawji et al., 1999258Nonrandomized study that did not attempt to control for possible baseline differences between groups
Kaynak et al., 2007259Did not address any Key Question
Khajanchee et al., 2001260Nonrandomized study that did not attempt to control for possible baseline differences between groups
Khajanchee et al., 2004261Nonrandomized study that did not attempt to control for possible baseline differences between groups
Khan et al., 2006262Nonrandomized study that did not attempt to control for possible baseline differences between groups
Khan et al., 2010263Nonrandomized study that did not attempt to control for possible baseline differences between groups
Khoury et al., 1995264Nonrandomized study that did not attempt to control for possible baseline differences between groups
Kimura et al., 1998265Nonconcurrent enrollment
Kingsley et al., 1998266Did not address any Key Question
Kingsnorth et al., 1992267Did not address any Key Question
Kingsnorth et al., 1999268Clinical comment
Kingsnorth et al., 2000269Unable to locate
Kingsnorth et al., 2002270Anesthesia
Kiruparan et al., 1998271Nonconcurrent enrollment
Klein et al., 2002272Anesthesia
Klin et al., 2010273Background
Knapp et al., 1976274Anesthesia
Knock et al., 1999275Case series
Kocijan et al., 2010276Case series
Koinig et al., 2000277Anesthesia
Koning et al., 2010278Nonrandomized study that did not attempt to control for possible baseline differences between groups
Korenstein et al., 2008279Did not address any Key Question
Korman et al., 1997280Did not address any Key Question
Koukourou et al., 2001281Did not address any Key Question
Kovacs et al., 1997282Did not address any Key Question
Kozol et al., 1997283Did not address any Key Question
Krahenbuhl et al., 1997284Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Krahenbuhl et al., 1998285Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Krane et al., 1995286Anesthesia
Krupinski et al., 1997287Did not address any Key Question
Kucuk et al., 2010288Did not address any Key Question
Kuhry et al., 2007289Review
Kumar et al., 1997290Anesthesia
Kumar et al., 2002291Nonrandomized study that did not attempt to control for possible baseline differences between groups
Kunz et al., 1993292Did not address any Key Question
Kux et al., 1994293Did not address any Key Question
Kuzu et al., 2005294Antibiotics
Lai et al., 1998295Did not address any Key Question
Lange et al., 2005296Nonrandomized study that did not attempt to control for possible baseline differences between groups
Lange et al., 2011297Review
Lau et al., 2000298Did not focus sufficiently on a patient population of interest (44% of the TEP group, 14/32, had recurrent hernia, and the other 56% had primary hernia).
Lau et al., 2001299Did not address any Key Question
Lau et al., 2002300Anesthesia
Lau et al., 2002301Nonrandomized study that did not attempt to control for possible baseline differences between groups
Lau et al., 2002302Nonrandomized study that did not attempt to control for possible baseline differences between groups (only controlled for age)
Lau et al., 2003303Case series
Lau et al., 2003304Review
Lau et al., 2003305Nonrandomized study that did not attempt to control for possible baseline differences between groups
Lau et al., 2003306Confounding by indication: patient clinical factors decided treatment assignment
Lau et al., 2005307Only included females
Lauscher et al., 2008308Nonrandomized study that did not attempt to control for possible baseline differences between groups
Lauscher et al., 2008309Nonconcurrent enrollment
Lawrence et al., 1995310Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Lawrence et al., 1996311Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Lawrence et al., 1997312Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Lazorthes et al., 1992313Antibiotics
Lee et al., 2002314Did not address any Key Question
Lee et al., 2010315Case series
Leibl et al., 2000316Did not address any Key Question
Leibl et al., 2005317Narrative review
Lepere et al., 2000318Nonrandomized study that did not attempt to control for possible baseline differences between groups
Lepere et al., 2008319Did not address any Key Question
Lerut et al., 1998320Narrative review
Liebl et al., 1999321Review
Lin et al., 1993322Anesthesia
Lin et al., 1998323Anesthesia
Lin et al., 2011324Nonrandomized study that did not attempt to control for possible baseline differences between groups
Litwin et al., 1994325Data were considering for the surgical experience question, however of the 317 patients undergoing laparoscopic repair, data related to surgical experience were only reported for 40 of them, and the reason for this selection was not reported.
Liu et al., 1992326Did not address any Key Question
Liu et al., 1994327Case series
Ljem et al., 1997328Did not address any Key Question
Lobe et al., 1992329Case series
Lorenz et al., 2000330Did not address any Key Question
Lotan et al., 2004331Case series
Lowham et al., 1997332Narrative review
Lugo Vicente et al., 1995333Case series
Lukaszczyk et al., 1996334Confounding by indication: patient clinical factors decided treatment assignment
Machotta et al., 2003335Anesthesia
Maddern et al., 1993336Did not address any Key Question
Maddern et al., 1994337Did not address any Key Question
Maddox et al., 2008338Case series
Maggiore et al., 2001339Did not address any Key Question
Mahon et al., 2003340Considered for the comparison of laparoscopic and open repair for bilateral and recurrent hernia, however the data were not reported separately for these two conditions. Overall 79% of hernias were bilateral (156/198, and 14 of the 156 were also recurrent). Overall, 28% of hernias were recurrent (56/198, and 14 of the 56 were also bilateral).
Malviya et al., 1992341Anesthesia
Mann et al., 1998342Narrative review
Mann et al., 1998343Did not focus sufficiently on a patient population of interest (24% or 12/51 had recurrent hernia, and the other 76% had primary hernia)
Marappan et al., 1996344Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Markar et al., 2010345Review
Markey et al., 1997346Anesthesia
Massaron et al., 2007347Nonconcurrent enrollment
Massaron et al., 2008348Nonconcurrent enrollment
Matsota et al., 2007349Anesthesia
Matyja et al., 2010350Nonrandomized study that did not attempt to control for possible baseline differences between groups
Mayagoitia et al., 2004351Nonrandomized study that did not attempt to control for possible baseline differences between groups
Mayagoitia et al., 2006352Nonrandomized study that did not attempt to control for possible baseline differences between groups
McCormack et al., 2005353Review
McCormack et al., 2005354Review
McCormack et al., 2008355Review
McGillicuddy et al., 1998356Did not address any Key Question
McIntosh et al., 1998357Comment on cost measurement
McIntosh et al., 2000358Did not address any Key Question
McNally et al., 2009359Nonrandomized study that did not attempt to control for possible baseline differences between groups
Mellinger et al., 2004360Clinical comment
Memon et al., 1999361Did not report data comparing the procedures
Memon et al., 2003362Review
Menakuru et al., 2006363Case series
Merello et al., 1997364Abstract only
Merhav et al., 1993365Anesthesia
Metzger et al., 2001366Did not address any Key Question
Miedema et al., 2004367Did not address any Key Question
Miguel et al., 1998368Case series
Mikkelsen et al., 1996369Anesthesia
Millikan et al., 1994370Did not address any Key Question
Miltenberg et al., 1998371Review
Miyazaki et al., 2001372Did not address any Key Question
Mok et al., 1998373Nonrandomized study that did not attempt to control for possible baseline differences between groups
Mokete et al., 2001374Did not address any Key Question
Mollen et al., 2007375Narrative review contralateral
Montupet et al., 2011376Case series
Moores et al., 1990377Anesthesia
Morgan et al., 1991378Did not address any Key Question
Muller-Riemenschneider et al., 2007379Incisional hernia
Mulroy et al., 1999380Anesthesia
Murat et al., 2005381Anesthesia
Muzio et al., 2006382Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Naguib et al., 1991383Anesthesia
Naguib et al., 1995384Anesthesia
Naja et al., 2005385Anesthesia
Nathanson et al., 1996386Did not address any Key Question
Nazir et al., 1996387Case series
Neagu et al., 2000388Unable to verify
Negro et al., 2011389Nonrandomized study that did not attempt to control for possible baseline differences between groups
Newman et al., 1993390Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Nicholson et al., 1999391Did not address any Key Question
Nienhuijs et al., 2005392Case series
Nienhuijs et al., 2007393Review
Nishimura et al., 2000394Did not address any Key Question
Nixon et al., 2009395Nonrandomized study that did not attempt to control for possible baseline differences between groups
Niyogi et al., 2010396Did not address any Key Question
Nordin et al., 2002397Did not address any Key Question
Nordin et al., 2003398Anesthesia
Nordin et al., 2004399Anesthesia
Nordin et al., 2007400Anesthesia
Nordin et al., unpublished401Did not address any Key Question
Nyhus et al., 1993402Background
Oberg et al., 2005403Case series
Obrist et al., 2011404Abstract only
O’Dwyer et al., 2003405Anesthesia
Oehlenschlager et al., 2010406Did not address any Key Question
Ohana et al., 2006407Did not address any Key Question
O’Hanlon et al., 1996408Anesthesia
O’Riordain et al., 1998409Anesthesia
Osuigwe et al., 2006410Antibiotics
Ozcengiz et al., 2001411Anesthesia
Ozgediz et al., 2007412Did not address any Key Question
Ozgun et al., 2002413Anesthesia
Ozkan et al., 2009414Anesthesia
Ozmen et al., 2011415Abstract only
Paajanen, 2003416Did not address any Key Question
Paajanen et al., 2010417Nonrandomized study with a multivariate analysis but it did not specifically address any Key Questions (e.g., the open vs laparoscopic comparison in the multivariate analysis included many non-mesh procedures).
Page et al., 2002418Did not address any Key Question
Paily et al., 2009419Case series
Pala et al., 2009420Anesthesia
Panos et al., 1992421Did not address any Key Question
Panton et al., 1994422Case series
Papachristou et al., 2002423Confounding by indication
Papaziogas et al., 2004424Did not address any Key Question
Pappalardo et al., 1999425Case series
Pardieck et al., 1998426Case series
Passariello et al., 2004427Anesthesia
Paul et al., 1994428Did not address any Key Question
Pawanindra et al., 2010429Did not address any Key Question
Payne et al., 1992430Anesthesia
Payne et al., 1996431Abstract only
Peiper et al., 1994432Anesthesia
Pelissier et al., 2006433Case series
Perez et al., 2005434Antibiotics
Perko et al., 2011435Did not address any Key Question
Pessaux et al., 2006436Antibiotics
Pet≤hßzi et al., 1999437Case series
Picchio et al., 2004438Neurectomy
Pierides et al., 2011439Duplicate of already included article
Platt et al., 1990440Antibiotics
Podolsky et al., 2010441Did not address any Key Question
Polat et al., 2003442Did not report any outcomes of interest
Poobalan et al., 2001443Did not address any Key Question
Poobalan et al., 2003444Review
Pradhan et al., 2008445Anesthesia
Praveen et al., 2009446Antibiotics
Prieto-Díaz-Chávez et al., 2005447Did not address any Key Question
Prieto-Diaz-Chavez et al., 2009448Did not address any Key Question
Prior et al., 1998449Did not address any Key Question
Pullyblank et al., 2002450Case series
Purkayastha et al., 2008451Review
Quilici et al., 1993452Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Quilici et al., 1996453Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Quilici et al., 2000454Did not report data comparing the procedures
Rahr et al., 2006455Did not report any outcomes of interest
Rajapandian et al., 2010456Case series
Ramon et al., 1998457Abstract only
Ramshaw et al., 1995458Nonconcurrent enrollment
Ramshaw et al., 1996459Nonconcurrent enrollment
Ramshaw et al., 1996460Case series
Ramshaw et al., 1996461Nonconcurrent enrollment
Ravichandran et al., 2000462Neurectomy
Richards et al., 2004463Nonrandomized study that did not attempt to control for possible baseline differences between groups
Rizk et al., 1994464Did not address any Key Question
Rogers et al., 1998465Fewer than 10 patients enrolled in at least one of the relevant groups
Romsing et al., 2001466Anesthesia
Ron et al., 2007467Risk of developing pediatric contralateral hernia
Rose et al., 1999468Case series
Rosen et al., 2001469Did not report any outcomes of interest
Rosenberg et al., 2008470Background
Rowbotham et al., 1998471Anesthesia
Rudkin et al., 1995472Did not address any Key Question
Ruhanen et al., 1994473Anesthesia
Rukas et al., 2000474Unable to verify
Rulli et al., 1998475Did not address any Key Question
Rutkow et al., 1993476Did not address any Key Question
Rutkow et al., 1995477Case series
Rutkow et al., 2003478Not an empirical study
Saad et al., 1999479Case series
Saad et al., 2011480Case series
Saadawy et al., 2009481Anesthesia
Saggar et al., 2008482Nonrandomized study that did not attempt to control for possible baseline differences between groups
Salameh et al., 2002483Did not report how many open repairs involved a mesh
Sale et al., 2006484Did not address any Key Question
Sanabria et al., 2007485Review
Sanchez-Manuel et al., 2009486Review
Sandbichler et al., 1996487Case series
Sandenaa et al., 2001488Did not address any Key Question
Santoro et al., 2007489Nonconcurrent enrollment
Saranga Bharathi et al., 2008490Nonrandomized study that did not attempt to control for possible baseline differences between groups
Saranga Bharathi et al., 2008491Background
Sarli et al., 2001492Simultaneous cholecystectomy
Savarise et al., 2001493Nonrandomized study that did not attempt to control for possible baseline differences between groups
Schafer et al., 2010494Review
Schindler et al., 1991495Anesthesia
Schmedt et al., 2002496Review
Schmedt et al., 2005497Review
Schmidt et al., 2006498Nonconcurrent enrollment
Schneider et al., 2003499Did not focus sufficiently on a patient population of interest (21% of patients, 12/56, had recurrent hernia, and the other 79% had primary hernia, and data were not reported separately)
Schrenk et al., 1996500Did not address any Key Question
Schroder et al., 2004501Did not address any Key Question
Schultz et al., 1995502Nonrandomized study that did not attempt to control for possible baseline differences between groups
Schurz et al., 1995503Did not report whether mesh was used for open hernia repair
Schwab et al., 2004504Did not address any Key Question
Schwab et al., 2006505Nonconcurrent enrollment
Schwab et al., 2008506Simulated hernia repair
Schwobel et al., 1999507Case series
Scott et al., 1989508Anesthesia
Scott et al., 2008509Review
Shah et al., 2009510Nonrandomized study that did not attempt to control for possible baseline differences between groups
Shah et al., 2011511Nonrandomized study that did not attempt to control for possible baseline differences between groups
Shamim et al., 2006512Did not address any Key Question
She et al., 2011513Nonrandomized study that did not attempt to control for possible baseline differences between groups
Shehata et al., 2011514Abstract only
Sherwinter et al., 2010515Nonconcurrent enrollment
Simons et al., 1996516Did not address any Key Question
Sinclair et al., 1988517Anesthesia
Sinha et al., 2006518Nonrandomized study that did not attempt to control for possible baseline differences between groups
Smedburg et al., 1984519Did not address any Key Question
Smeds et al., 2010520Did not address any Key Question
Smith et al., 2001521Nonrandomized study that did not attempt to control for possible baseline differences between groups
Somri et al., 1998522Anesthesia
Sondenaa et al., 2001488Did not address any Key Question
Song et al., 2000523Anesthesia
Sosa et al., 1994524Case series
Spittal et al., 1992525Anesthesia
Splinter et al., 1995526Anesthesia
Srsen et al., 2008527Did not focus sufficiently on a patient population of interest (17% of patients, 36/216, had recurrent hernia, and the other 83% had primary hernia, and data were not reported separately)
Staerkle et al., 2009528Case series
Stark et al., 1999529Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Steinau et al., 1999530Case series
Stengel et al., 2004531Review
Stoker et al., 1994532Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Stoppa et al., 1998533Background
Stylopoulos et al., 2003534Cost-effectiveness analysis
Subwongcharoen et al., 2002535Nonrandomized study that did not attempt to control for possible baseline differences between groups
Sucullu et al., 2010536Did not report any outcomes of interest
Surana et al., 1993537Case series
Tagaya et al., 1995538Nonrandomized study that did not attempt to control for possible baseline differences between groups
Tai et al., 2011539Nonrandomized study that did not attempt to control for selection bias
Takahara et al., 1995540Did not address any Key Question
Tammadon et al., 2005541Case series
Tamme et al., 2005542Nonrandomized study that did not attempt to control for possible baseline differences between groups
Tanovia et al., 2005543Did not address any Key Question
Tanphiphat et al., 1998544Did not address any Key Question
Tantia et al., 2009545Did not report any outcomes comparing procedures
Taylor et al., 1997546Antibiotics
Teasdale et al., 1982547Anesthesia
Terzi et al., 2005548Antibiotics
Tetik et al., 1994549Nonrandomized study that did not attempt to control for possible baseline differences between groups
Thaha et al., 2008550Review
Thapar et al., 2000551Did not address any Key Question
Thill et al., 1994552Did not address any Key Question
Topal et al., 1997553Case series
Topart et al., 2005554Nonconcurrent enrollment
Toufique et al., 2009555Case series
Toy et al., 1996556Case series
Tran et al., 1992557Did not address any Key Question
Triantafyllidis et al., 2011558Abstract only
Tsai et al., 2010559Nonrandomized study that did not attempt to control for possible baseline differences between groups
Tsakayannis et al., 2004560Neurectomy
Tschudi et al., 1996561Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Tucker et al., 1995562Case series
Turial et al., 2011563Case series
Twersky et al., 1995564Anesthesia
Tzovaras et al., 2007565Antibiotics
Ulman et al., 1995566Case series
Unknown author et al., 2004567Trial synopsis
Ure et al., 2000568Did not address any Key Question
Vale et al., 2003569Review
Vale et al., 2004570Did not address any Key Question
Vallribrera et al., 1997571Did not address any Key Question
van den Heuvel et al., 2011572Narrative review
Van Den Tol et al., 1996573Did not address any Key Question
van der Pool et al., 2010574Case series
van der Zwaal et al., 2008575Nonrandomized study that did not attempt to control for possible baseline differences between groups
Van Hee et al., 1998576Nonrandomized study that did not attempt to control for possible baseline differences between groups
van Veen et al., 2007577Did not address any Key Question
van Veen et al., 2007578Did not address any Key Question
van Veen et al., 2008579Anesthesia
Varshney et al., 1995580Did not address any Key Question
Velanovich et al., 2000581Confounding by indication
Velanovich et al., 2006582Nonrandomized study that did not attempt to control for possible baseline differences between groups
Velasco et al., 1996583Nonconcurrent enrollment
Velasco et al., 1998584Case series
Vidovic et al., 2007585Nonrandomized study that did not attempt to control for possible baseline differences between groups
Vincent et al., 2003586Did not address any Key Question
Vogt et al., 1996587Did not address any Key Question
Voyles et al., 2002588Review
Vrijland et al., 2002589Did not address any Key Question
Waechter et al., 2001590Anesthesia
Wake et al., 2008591Review
Wassef et al., 1998592Anesthesia
Webb et al., 1999593Review protocol
Weiland et al., 1998594Wound closure
Welborn et al., 1990595Anesthesia
Weldon et al., 2004596Anesthesia
Wennstrom et al., 2004597Did not address any Key Question
Weyhe et al., 2007598Narrative review
Weyhe et al., 2007599Nonrandomized study that did not attempt to control for possible baseline differences between groups
Wheeler et al., 1993600Case series
Willaert et al., 2009601Review protocol
Williams et al., 1999602Survey of beliefs
Williams et al., 2001603Anesthesia
Wilson et al., 1995604Nonrandomized study that did not attempt to control for possible baseline differences between groups
Wilson et al., 2010605Did not address any Key Question
Winslow et al., 2004606Surgical experience data not on hernia recurrence but on other outcomes such as operation time or other complications
Witkowski et al., 2000607Unable to verify
Woods et al., 2008608Narrative review
Wulkan et al., 1996609Case series
Yamamoto et al., 2002610Nonrandomized study that did not attempt to control for possible baseline differences between groups
Yerdel et al., 2001611Antibiotics
Zampieri et al., 2008612Case series
Zeybek et al., 2008613Did not address any Key Question
Zhao et al., 2009614Review
Zhu et al., 2009615Did not report any outcomes of interest
Zib et al., 2002616Review
Zieren et al., 2003617Case series
Zigman et al., 1998618Case series
Zollinger et al., 2003619Background
Zwaal et al., 2008620Nonrandomized study that did not attempt to control for possible baseline differences between groups

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