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Saha S, Smith MEB, Totten A, et al. Pressure Ulcer Treatment Strategies: Comparative Effectiveness [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2013 May. (Comparative Effectiveness Reviews, No. 90.)
This publication is provided for historical reference only and the information may be out of date.
The following databases have been searched for relevant information:
Search strategies are presented for the original searches. An updated search was conducted on June 5th, 2012.
Medline
Searched: Ovid MEDLINE(R) and Ovid OLDMEDLINE(R) 1946 to August Week 5 2011
Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations September 12, 2011
Date Searched: September 14, 2011
Updated Searches: June 5th, 2012 and October 17th, 2012
| 1 | Pressure Ulcer/dh, dt, nu, rt, rh, su, th, ae, co, in, mo, po, to | 4917 |
| 2 | pressure ulcer/ and (treatment or healing or management or therapy).hw. | 1818 |
| 3 | ((pressure ulcer$ or pressure sore$ or bed sore$ or bedsore$ or decubitus ulcer$) adj5 (treat$ or heal$ or manag$ or therap$)).ti,ab. | 2244 |
| 4 | 1 or 2 or 3 | 6047 |
| 5 | limit 4 to yr=“1985 -Current” | 4876 |
| 6 | remove duplicates from 5 | 4668 |
EMBASE
Searched: Embase (Elsevier)
Date Searched: September 14, 2011
Updated Search: June 5th, 2012
| 6 | ((‘pressure ulcer?’ OR ‘pressure sore?’ OR ‘bed sore?’ OR bedsore? OR decubitus) NEAR/5 (treat* OR heal* OR manag* OR therap* OR surger*)):ab,ti AND [embase]/lim OR (‘decubitus’/mj AND (‘radiotherapy’:de OR ‘drug therapy’:de OR ‘therapy’:de OR ‘magnetotherapy’:de OR ‘treatment outcome’:de OR ‘palliative therapy’:de OR ‘treatment failure’:de OR ‘treatment response’:de OR ‘wound healing impairment’:de OR ‘healing’:de OR ‘ulcer healing’:de OR ‘wound healing’:de OR ‘wound care’:de OR ‘wound healing promoting agent’:de OR ‘vacuum assisted closure’:de OR ‘surgery’:de OR ‘ultrasound therapy’:de OR ‘diet therapy’:de OR ‘malnutrition’:de OR ‘debridement’:de OR ‘wound dressing’:de) AND [embase]/lim) AND (1985:py OR 1986:py OR 1987:py OR 1988:py OR 1989:py OR 1990:py OR 1991:py OR 1992:py OR 1993:py OR 1994:py OR 1995:py OR 1996:py OR 1997:py OR 1998:py OR 1999:py OR 2000:py OR 2001:py OR 2002:py OR 2003:py OR 2004:py OR 2005:py OR 2006:py OR 2007:py OR 2008:py OR 2009:py OR 2010:py OR 2011:py) | 1,739 |
| 5 | ((‘pressure ulcer?’ OR ‘pressure sore?’ OR ‘bed sore?’ OR bedsore? OR decubitus) NEAR/5 (treat* OR heal* OR manag* OR therap* OR surger*)):ab,ti AND [embase]/lim OR (‘decubitus’/mj AND (‘radiotherapy’:de OR ‘drug therapy’:de OR ‘therapy’:de OR ‘magnetotherapy’:de OR ‘treatment outcome’:de OR ‘palliative therapy’:de OR ‘treatment failure’:de OR ‘treatment response’:de OR ‘wound healing impairment’:de OR ‘healing’:de OR ‘ulcer healing’:de OR ‘wound healing’:de OR ‘wound care’:de OR ‘wound healing promoting agent’:de OR ‘vacuum assisted closure’:de OR ‘surgery’:de OR ‘ultrasound therapy’:de OR ‘diet therapy’:de OR ‘malnutrition’:de OR ‘debridement’:de OR ‘wound dressing’:de) AND [embase]/lim) | 2,263 |
| 4 | ‘decubitus’/mj AND (‘radiotherapy’:de OR ‘drug therapy’:de OR ‘therapy’:de OR ‘magnetotherapy’:de OR ‘treatment outcome’:de OR ‘palliative therapy’:de OR ‘treatment failure’:de OR ‘treatment response’:de OR ‘wound healing impairment’:de OR ‘healing’:de OR ‘ulcer healing’:de OR ‘wound healing’:de OR ‘wound care’:de OR ‘wound healing promoting agent’:de OR ‘vacuum assisted closure’:de OR ‘surgery’:de OR ‘ultrasound therapy’:de OR ‘diet therapy’:de OR ‘malnutrition’:de OR ‘debridement’:de OR ‘wound dressing’:de) AND [embase]/lim | 1,528 |
| 3 | ((‘pressure ulcer?’ OR ‘pressure sore?’ OR ‘bed sore?’ OR bedsore? OR decubitus) NEAR/5 (treat* OR heal* OR manag* OR therap* OR surger*)):ab,ti AND [embase]/lim | 1,439 |
| 2 | ‘radiotherapy’:de OR ‘drug therapy’:de OR ‘therapy’:de OR ‘magnetotherapy’:de OR ‘treatment outcome’:de OR ‘palliative therapy’:de OR ‘treatment failure’:de OR ‘treatment response’:de OR ‘wound healing impairment’:de OR ‘healing’:de OR ‘ulcer healing’:de OR ‘wound healing’:de OR ‘wound care’:de OR ‘wound healing promoting agent’:de OR ‘vacuum assisted closure’:de OR ‘surgery’:de OR ‘ultrasound therapy’:de OR ‘diet therapy’:de OR ‘malnutrition’:de OR ‘debridement’:de OR ‘wound dressing’:de AND [embase]/lim | 2,565,030 |
| 1 | ‘decubitus’/mj AND [embase]/lim | 3,001 |
CINAHL
Searched: EBSCOHost CINAHL Plus with Full Text
Date Searched: September 14, 2011
Updated Search: June 5th, 2012
| S6 | S1 or S2 or S5 | Limiters - Published Date from: 19850101–20111231 Search modes - Boolean/Phrase | 1197 |
| S5 | S3 or S4 | Limiters - Search Only Pre-CINAHL Search modes - Boolean/Phrase | 22 |
| S4 | (AB “pressure ulcer*” or AB “pressure sore*” or AB “bed sore*” or AB “bedsore*” or AB “decubitus ulcer*”) and (AB “treat*” or AB “heal*” or AB “manag*” or AB “therapy” or AB “therapies”) | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | 658 |
| S3 | (TI “pressure ulcer*” or TI “pressure sore*” or TI “bed sore*” or TI “bedsore*” or TI “decubitus ulcer*”) and (TI “treat*” or TI “heal*” or TI “manag*” or TI “therapy” or TI “therapies”) | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | 449 |
| S2 | (MM “Pressure Ulcer”) and (MW “treatment” or MW “healing” or MW “management” or MW “therapy” or MW “therapeutic”) | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | |
| S1 | (MH “Pressure Ulcer/CO/DH/DT/MO/NU/RT/RH/SU/TH”) | Limiters - Exclude MEDLINE records Search modes - Boolean/Phrase | 1013 |
EBM Reviews
Searched:
EBM Reviews - Cochrane Database of Systematic Reviews 2005 to August 2011,
EBM Reviews - Database of Abstracts of Reviews of Effects 3rd Quarter 2011,
EBM Reviews - Cochrane Central Register of Controlled Trials 3rd Quarter 2011,
EBM Reviews - Health Technology Assessment 3rd Quarter 2011,
EBM Reviews - NHS Economic Evaluation Database 3rd Quarter 2011
Date Searched: September 14, 2011
Updated Search: June 5th, 2012
| 1 | Pressure Ulcer/dh, dt, nu, rt, rh, su, th, ae, co, in, mo, po, to | 262 |
| 2 | Pressure ulcer/ and (treatment or healing or management or therapy).hw. | 184 |
| 3 | ((pressure ulcer$ or pressure sore$ or bed sore$ or bedsore$ or decubitus ulcer$) adj5 (treat$ or heal$ or manag$ or therap$)).ti,ab. | 363 |
| 4 | 1 or 2 or 3 | 501 |
| 5 | limit 4 to yr=“1985 -Current” | 470 |
| 6 | remove duplicates from 5 | 466 |
ClinicalTrials.gov
Searched 09/15/2011
Update Search 06/05/2012
( ( NOT ( “Recruiting” OR “Not yet recruiting” OR “Available” ) ) [OVERALL-STATUS] AND pressure ulcer* OR decubitus ulcer* OR pressure sore* OR bedsore* OR bed sore* [DISEASE] ) [ALL-FIELDS]
Results = 184
Current Controlled Trials
Searched 09/15/2011
Update Search 06/05/2012
Search box: pressure ulcer*, decubitus ulcer*, pressure sore*, bedsore*, bed sore*
Selected all registries with the exception of Nih’s ClinicalTrials.gov
Results = 8, which were then edited to treatment trials
ClinicalStudyResults.org
Searched 09/15/2011
Update Search 06/04/2012
Studies Indications or Disease: two searches:
#1: Ulcers, Pressure
#2: Ulcers, Diabetic and Decubitus (bedsores)
Results: neither search returned any results
WHO ICTRP
Searched 09/15/2011
Update Search 06/05/2012
Search terms:
Condition search box, two separate searches: decubitus ulcers, pressure ulcers
Recruitment status: ALL
Results = 79, which were then edited to treatment trials
Notes: search interface gave inconsistent and unexpected results, based on documentation.
ProQuest CSA Conference Papers Index
Searched: ProQuest CSA Conference Papers Index
Date Searched: 9/19/2011
Updated Search: 06/05/2012
Search Query #9 KW=(pressure ulcer* or pressure sore* or bed sore* or bedsore* or decubitus ulcer*) and KW=(treat* or heal* or surger* or surgical* or diet* or nutrition* or manag* or therap* or pressure or mattress* or cushion* or surface* or gel* or bandage* or dressing* or foam* or maggot* or debrid* or silver or saline or vibration* or cream*) and not Q1=(screening or prevention or risk assessment or classification or diabetes mellitus or training or quality of life or animal studies) (Copy Query)
241 Published Works results found in Conference Papers Index
Date Range: 1985 to 2012
ProQuest Dissertations & Theses
Searched 09/16/2011
Search terms:
(decubitus ulcer* or pressure ulcer* or pressure sore* or bedsore* or bed sore*) AND (treat* or therap* or manag* or heal*)
Details of the Search Process
A research Librarian, developed a list of databases to be searched and tested database specific search strategies in collaboration with the research team. Additional references were found by hand-searching the bibliographies of review articles and included studies; letters to the editor and commentaries; and Technical Expert Panel input.
All citations were imported into Thomson Reuters’ EndNote X3 (citation management) and then Distiller Systematic Review Software (screening of abstracts and full text, kappa calculation, data extraction, exclusion reports, and table construction).
Search Strategy Development Notes
A combination of controlled vocabulary and keywords were employed in the search strategies, with age, study methodology, and date (2002-) limits applied. No language limit was used. Details of the search strategies are given in Appendix A.
List of Databases Searched
Table A-1Databases searched
| Name | Date Searched | Platform Provider |
|---|---|---|
| Bibliographic Database Search | ||
| Medline | 1947-02/28/2011; Update Search 06/05/2012 | OvidSP |
| Embase | 1976-04/11/2011; Update Search 06/05/2012 | Elsevier |
| Cochrane Library/EBM Reviews: Cochrane Central Register of Controlled Trials (CCRCT) | 1991-04/11/2011; Update Search 06/05/2012 | OvidSP |
| Cochrane Library/EBM Reviews: Cochrane Database of Systematic Reviews (CDSR) | 2005-04/11/2011; Update Search 06/05/2012 | OvidSP |
| Cochrane Library/EBM Reviews: Database of Abstracts of Reviews of Effects (DARE) | 1991-04/11/2011; Update Search 06/05/2012 | OvidSP |
| Citation Database Search | ||
| Scopus | 1960-04/11/2011; Update Search 06/05/2012 | Elsevier |
| Subject Specific Database Search | ||
| PsycINFO | 1806-04/12/2011; Update Search 06/05/2012 | OvidSP |
Grey Literature (Unpublished Literature) Strategy
In addition to searching bibliographic, citation, and subject-specific databases, additional materials were sought by searching for regulatory information, clinical trial registries, and conference proceedings. Including the following databases and websites:
Table A-2Grey literature searched
| Name | Date Searched | Platform Provider |
|---|---|---|
| Clinical Trial Registries | ||
| Clinicaltrials.gov | Original Search 03/02/2011 Update Search 06/05/2012 | US National Institutes of Health |
| Regulatory Agencies | ||
| Drug Approval Package | Original Search 03/02/2011 Update Search 05/052012 | US Federal Drug Administration |
| European Public Assessment Reports | Original Search 03/02/2011 Update Search 04/06/2012 | European Medicines Agency |
| Summary Basis of Decision (SBD): Drugs | Original Search 03/02/2011 Update Search 06/05/2012 | Health Canada |
| Conference Proceedings | ||
| Scopus | 1960-April 11, 2011; Update Search 06/05/2012 | Elsevier |
Scientific Information Packets (SIPs)
The Effective Health Care Program Scientific Resource Center requested information about published and unpublished Phase II and above clinical studies, post-marketing studies, and observational studies from pharmaceutical companies. The SIP request deadline had not yet passed when this draft report was written, the final report will be updated with all relevant information derived from SIP submissions.
Hyperbaric Oxygenation Search Strategy
| 1 | Pressure Ulcer/dh, dt, nu, rt, rh, su, th, ae, co, in, mo, po, to | 4899 |
| 2 | pressure ulcer/ and (treatment or healing or management or therapy).hw. | 1892 |
| 3 | ((pressure ulcer$ or pressure sore$ or bed sore$ or bedsore$ or decubitus ulcer$) adj5 (treat$ or heal$ or manag$ or therap$)).ti,ab. | 2266 |
| 4 | 1 or 2 or 3 | 6087 |
| 5 | limit 4 to yr=“1985 -Current” | 4963 |
| 6 | remove duplicates from 5 | 4920 |
| 7 | hyperbaric$.ti,ab,hw. | 13131 |
| 8 | Hyperbaric Oxygenation/ | 9635 |
| 9 | 7 or 8 | 13131 |
| 10 | 6 and 9 | 24 |
- Medline
- EMBASE
- CINAHL
- EBM Reviews
- ClinicalTrials.gov
- Current Controlled Trials
- ClinicalStudyResults.org
- WHO ICTRP
- ProQuest CSA Conference Papers Index
- ProQuest Dissertations & Theses
- Details of the Search Process
- Search Strategy Development Notes
- List of Databases Searched
- Grey Literature (Unpublished Literature) Strategy
- Scientific Information Packets (SIPs)
- Hyperbaric Oxygenation Search Strategy
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- List of Devices - Methods for Insulin Delivery and Glucose Monitoring: Comparati...List of Devices - Methods for Insulin Delivery and Glucose Monitoring: Comparative Effectiveness
- Search Results - Social and Structural Determinants of Maternal Morbidity and Mo...Search Results - Social and Structural Determinants of Maternal Morbidity and Mortality: An Evidence Map
- Summary Table for Modifiers of Effectiveness - Treatment Strategies for Women Wi...Summary Table for Modifiers of Effectiveness - Treatment Strategies for Women With Coronary Artery Disease
- Detailed Electronic Database Search Strategies - Methods for Insulin Delivery an...Detailed Electronic Database Search Strategies - Methods for Insulin Delivery and Glucose Monitoring: Comparative Effectiveness
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