Regulatory Information

• FDA
  Source: http://www.fda.gov/default.htm
  Date searched: 5/15/2012
  Search strategy: key word “PCA3”
  Records: 219

Clinical trial registries

• NIH database
  Source: http://clinicaltrials.gov/
  Date searched: 5/15/2012
  Search strategy: PCA3 [ALL-FIELDS] AND “Completed” [OVERALL-STATUS]
  Records: 6
• BioMed central
  Source: http://www.controlled-trials.com/mrct/
  Date searched: 8/15/2011
  Search strategy: “PCA3” for completed trials
  Records: 0
• WHO International Clinical Trials Registry Platform Search Portal
  Source: http://apps.who.int/trialsearch/
  Date searched: 8/15/2011
  Search strategy: Search String = “PCA3” for ALL recruitment status trials
  Records: 0

Conference papers and abstracts

• American College of Medical Genetics (ACMG)
  Source: http://submissions.miracd.com/acmg/
  Date searched: 8/15/2011
  Search strategy: search string “PCA3 OR Prostate Cancer OR Prostate Cancer Screening”
  Records: 2
• American Society of Clinical Oncology (ASCO)
  Source: http://www.gucasym.org/PastSymposia.aspx
  Date searched: 8/15/2011
  Search strategy: search string “PCA3”
  Records: 6
• American Urological Association (AUA)
  Source: http://www.auanet.org/content/clinical-practice-guidelines/clinical-practice-guidelines.cfm
  Date searched: 8/15/2011
  Search strategy: search string “PCA3”
  Records: 26
• Association of Molecular Pathology (AMP)
  Source: http://www.amp.org/meetings/past_meetings.cfm
  Date searched: 8/15/2011
  Search strategy: not searchable without login
  Records: 0
• College of American Pathologists (CAP)
  Source: http://www.cap.org/apps/cap.portal?_nfpb=true&_pageLabel=reference
  Date searched: 8/15/2011
  Search strategy: search string “PCA3 OR Prostate Cancer OR Prostate Cancer Screening”
  Records: 240
• National Comprehensive Cancer Network (NCCN) Annual Congress
  Source: http://www.nccn.org/index.asp
  Date searched: 8/15/2011
  Search strategy: search string “PCA3”
  Records: 0
• Prostate Cancer Research Initiative (PCRI)
  Source: http://www.prostate-cancer.org/pcricms/
  Date searched: 8/15/2011
  Search strategy: search string “PCA3”
  Records: 0

Organizations publishing Guidance or Review Documents

• Agence d'évaluation des technologies et des modes d'intervention en santé (AETMIS)
  Source: http://www.aetmis.gouv.qc.ca/site/home.phtml
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 0
• Australia and New Zealand Horizon Scanning Network (ANZHSN)
  Source: http://www.horizonscanning.gov.au/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 0
• Canadian Agency for Drugs and Technologies in Health (CADTH)
  Source: http://cadth.ca/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 3 (all excluded; not relevant)
• The Cochrane Collaboration (Cochrane)
  Source: http://summaries.cochrane.org/
  Date searched: 8/15/2011
  Search strategy: search string string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR“differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 0
• European network for Health Technology Assessment (EUnetHTA)
  Source: http://www.eunethta.eu/Public/Search/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 0
• EuroGenTest
  Source: http://www.eurogentest.org/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 0
• National Guideline Clearinghouse (NGC)
  Source: http://www.guideline.gov/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”). – searches done in different combinations using the above combinations.
  Records: 4
• National Institute for Clinical Excellence (NICE)
  Source: http://www.nice.org.uk/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 1 (excluded; not relevant)
• United Kingdom Health Technology Assessment Programme (UK HTA)
  Source: http://www.hta.ac.uk/
  Date searched: 8/15/2011
  Search strategy: search string (“PCA3” OR “prostate cancer antigen 3” OR “DD3” OR “differential display code 3” OR “biomarkers”) AND (“prostate cancer” OR “prostatic cancer”).
  Records: 7

Government documents

• RePORTER
  Source: http://projectreporter.nih.gov/reporter.cfm
  Date searched: 8/15/2011
  Search strategy: key word “PCA3”
  Records: 26
• HSRPROJ
  Source: http://wwwcf.nlm.nih.gov/hsr_project/home_proj.cfm
  Date searched: 8/15/2011
  Search strategy: key word “PCA3”
  Records: 0
• AHRQ GOLD
  Source: http://gold.ahrq.gov/projectsearch/
  Date searched: 8/15/2011
  Search strategy: key word “PCA3”
  Records: 0

Manufacturer database

• Source: GenProbe Response to the Request for Scientific Information
  Date posted: 12/7/2011
  Date searched: Not applicable
  Search strategy: Not applicable
  Records: 27