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Structured Abstract
Objective:
To review and synthesize the state of research on a variety of meditation practices, including: the specific meditation practices examined; the research designs employed and the conditions and outcomes examined; the efficacy and effectiveness of different meditation practices for the three most studied conditions; the role of effect modifiers on outcomes; and the effects of meditation on physiological and neuropsychological outcomes.
Data Sources:
Comprehensive searches were conducted in 17 electronic databases of medical and psychological literature up to September 2005. Other sources of potentially relevant studies included hand searches, reference tracking, contact with experts, and gray literature searches.
Review Methods:
A Delphi method was used to develop a set of parameters to describe meditation practices. Included studies were comparative, on any meditation practice, had more than 10 adult participants, provided quantitative data on health-related outcomes, and published in English. Two independent reviewers assessed study relevance, extracted the data and assessed the methodological quality of the studies.
Results:
Five broad categories of meditation practices were identified (Mantra meditation, Mindfulness meditation, Yoga, Tai Chi, and Qi Gong). Characterization of the universal or supplemental components of meditation practices was precluded by the theoretical and terminological heterogeneity among practices. Evidence on the state of research in meditation practices was provided in 813 predominantly poor-quality studies. The three most studied conditions were hypertension, other cardiovascular diseases, and substance abuse. Sixty-five intervention studies examined the therapeutic effect of meditation practices for these conditions. Meta-analyses based on low-quality studies and small numbers of hypertensive participants showed that TM®, Qi Gong and Zen Buddhist meditation significantly reduced blood pressure. Yoga helped reduce stress. Yoga was no better than Mindfulness-based Stress Reduction at reducing anxiety in patients with cardiovascular diseases. No results from substance abuse studies could be combined. The role of effect modifiers in meditation practices has been neglected in the scientific literature. The physiological and neuropsychological effects of meditation practices have been evaluated in 312 poor-quality studies. Meta-analyses of results from 55 studies indicated that some meditation practices produced significant changes in healthy participants.
Conclusion:
Many uncertainties surround the practice of meditation. Scientific research on meditation practices does not appear to have a common theoretical perspective and is characterized by poor methodological quality. Firm conclusions on the effects of meditation practices in healthcare cannot be drawn based on the available evidence. Future research on meditation practices must be more rigorous in the design and execution of studies and in the analysis and reporting of results.
Contents
- Preface
- Acknowledgments
- Executive Summary
- 1. Introduction and Background
- 2. Methods
- 3. Results
- Topic I. The Practice of Meditation
- Mantra Meditation
- Mindfulness Meditation
- Yoga
- Tai Chi
- Qi Gong
- Characteristics of Meditation Practices
- Search Results for Topics II to V
- Topic II. State of Research on the Therapeutic Use of Meditation Practices in Healthcare
- Control Groups Used in Studies on Meditation Practices
- Topic III. Evidence on the Efficacy and Effectiveness of Meditation Practices
- Hypertension
- Cardiovascular Diseases
- Substance Abuse
- Methodological Quality of Included Studies
- Summary of the Results
- Topic IV. Evidence on the Role of Effect Modifiers for the Practice of Meditation
- Summary of the Results
- Topic V. Evidence on the Physiological and Neuropsychological Effects of Meditation Practices
- Summary of the Results
- 4. Discussion
- The Practice of Meditation
- State of Research on the Therapeutic Use of Meditation Practices in Healthcare
- Evidence on the Efficacy and Effectiveness of Meditation Practices
- Evidence on the Role of Effect Modifiers for the Practice of Meditation
- Evidence on the Physiological and Neuropsychological Effects of Meditation Practices
- Strengths and Limitations
- Future Research
- Conclusions
- Abbreviations
- Appendixes
- Appendix A. Technical Experts and Peer Reviewers
- Appendix B. Development of Consensus on a Set of Criteria for an Operational Definition of Meditation
- Appendix C. Exact Search Strings
- Appendix D. Review Forms
- Appendix E. Excluded Studies and Nonobtained Studies
- Appendix F. References of Multiple Publications (Topics II to V)
- Appendix G. Summary Tables for Topic II
- Appendix H. Characteristics of Clinical Trials of Meditation Practices for the Three Most Studied Conditions
- Appendix I. Characteristics of Studies Included in Topic V
- Appendix J. Characteristics of Studies on the Physiological and Neuropsychological Effects of Meditation Practices
- References and Included Studies
- List of Studies Potentially Relevant to the Review
Prepared for: Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services.1 Contract No. 290-02-0023. Prepared by: University of Alberta Evidence-based Practice Center Edmonton, Alberta, Canada.
Suggested citation:
Ospina MB, Bond TK, Karkhaneh M, Tjosvold L, Vandermeer B, Liang Y, Bialy L, Hooton N, Buscemi N, Dryden DM, Klassen TP. Meditation Practices for Health: State of the Research. Evidence Report/Technology Assessment No. 155. (Prepared by the University of Alberta Evidence-based Practice Center under Contract No. 290-02-0023.) AHRQ Publication No. 07-E010. Rockville, MD: Agency for Healthcare Research and Quality. June 2007.
This report is based on research conducted by the University of Alberta Evidence-based Practice Center (EPC) under contract to the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD (Contract No. 290-02-0023). The findings and conclusions in this document are those of the author(s), who are responsible for its contents, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.
The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.
This report may be used, in whole or in part, as the basis for development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.
The investigators have no relevant financial interests in the report. The investigators have no employment, consultancies, honoraria, or stock ownership or options, or royalties from any organization or entity with a financial interest or financial conflict with the subject matter discussed in the report.
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540 Gaither Road, Rockville, MD 20850. www
.ahrq.gov
- Review Clinical trials of meditation practices in health care: characteristics and quality.[J Altern Complement Med. 2008]Review Clinical trials of meditation practices in health care: characteristics and quality.Ospina MB, Bond K, Karkhaneh M, Buscemi N, Dryden DM, Barnes V, Carlson LE, Dusek JA, Shannahoff-Khalsa D. J Altern Complement Med. 2008 Dec; 14(10):1199-213.
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