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Coulter I, Hardy M, Shekelle P, et al. Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cancer. Rockville (MD): Agency for Healthcare Research and Quality (US); 2003 Aug. (Evidence Reports/Technology Assessments, No. 75.)

  • This publication is provided for historical reference only and the information may be out of date.

This publication is provided for historical reference only and the information may be out of date.

Cover of Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cancer

Effect of the Supplemental Use of Antioxidants Vitamin C, Vitamin E, and Coenzyme Q10 for the Prevention and Treatment of Cancer.

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Appendix B. Search Methodologies

Coenzyme Q10 And Cancer Prevention/Treatment Search Methodology

SEARCH #1 (PERFORMED 11/16/01)

DATABASES SEARCHED/TIME PERIOD COVERED:

MEDLINE1966-2001/Dec W2
MANTIS1880-2001/Aug
Allied & Complementary Medicine1984-2001/Dec
CancerLit1975-2001/Oct
CAB HEALTH1983-2001/Oct
TGG Health&Wellness DB1976-2001/Nov W1
Biosis Previews1969-2001/Nov W2
EMBASE1974-2001/Nov W2
Social SciSearch1972-2001/Nov W3
SciSearch Cited Ref Sci1990-2001/Nov W3
SciSearch Cited Ref Sci1974-1989/Dec
ELSEVIER BIOBASE1994-2001/Nov W2

SEARCH STRATEGY:

ubiquinone OR ubidecarenone OR coenzyme q10 OR co-enzyme q10 OR coenzyme q 10 OR co-enzyme q 10 OR coenzyme q-10 OR co-enzyme q-10

AND

neoplasms(exploded) from Medline OR malignant neoplastic disease(exploded) from Embase OR cancer* in title or subject heading field from all other databases (exception - In CancerLit the terms for cancer were omitted and just the total of “coenzyme q-10” terms were used”)

AND

Human

TOTAL NUMBER OF ITEMS RETRIEVED: 176

Vitamin C And Cancer Prevention/Treatment Search Methodology

SEARCH #2a (PERFORMED 11/27/01)

DATABASES SEARCHED/TIME PERIOD COVERED:

MEDLINE1966-2001/Dec W4
MANTIS1880-2001/Aug
Allied & Complementary Medicine1984-2001/Dec
CancerLit1975-2001/Oct
CAB HEALTH1983-2001/Oct
TGG Health&Wellness DB1976-2001/Nov W2
Biosis Previews1969-2001/Nov W3
EMBASE1974-2001/Nov W3
Social SciSearch1972-2001/Nov W4
SciSearch Cited Ref Sci1990-2001/Nov W4
SciSearch Cited Ref Sci1974-1989/Dec
ELSEVIER BIOBASE1994-2001/Nov W4

SEARCH STRATEGY:

ascorbic acid(exp loded)from Medline, Embase OR ascorbic acid from all other databases OR dehydroascorbic acid* OR ascorbate OR vitamin c OR antiscorbutic vitamin* OR cevitamic acid*

AND

neoplasms(exploded) from Medline OR malignant neoplastic disease(exploded) from Embase OR (cancer OR neoplasm*) in subject heading field from BIOSIS OR cancer* in title or subject heading field from all other databases OR neoplasm* from all other databases (exception - in CancerLit the terms for cancer were omitted and just the total of the “vitamin c” terms were used)

AND

(prevention OR preventive OR therapy OR therapeutic OR treatment) in title,subject heading fields

AND

human

TOTAL NUMBER OF ITEMS RETRIEVED: 1987

SEARCH #2b (PERFORMED 11/7/01)

DATABASES SEARCHED:

Cochrane Library

SEARCH STRATEGY:

vitamin c OR ascorbic acid OR ascorbate OR antiscorbutic vitamin OR cevitamic acid OR dehydroascorbic acid

AND

neoplasms(exploded)

TOTAL NUMBER OF ITEMS RETRIEVED:

The Cochrane Controlled Trials Register (CENTRAL/CCTR) References - 92

Vitamin E And Cancer Prevention/Treatment Search Methodology

SEARCH #3a (PERFORMED 12/13/01)

DATABASES SEARCHED/TIME PERIOD COVERED:

MEDLINE1966-2001/Jan W1
MANTIS1880-2001/Oct
Allied & Complementary Medicine1984-2001/Jan
CancerLit1975-2001/Oct
CAB HEALTH1983-2001/Oct
TGG Health&Wellness DB1976-2001/Nov W4
Biosis Previews1969-2001/Dec W2
EMBASE1974-2001/Dec W2
Social SciSearch1972-2001/Dec W3
SciSearch Cited Ref Sci1990-2001/Dec W3
SciSearch Cited Ref Sci1974-1989/Dec
ELSEVIER BIOBASE1994-2001/Dec W2

SEARCH STRATEGY:

Vitamin e (exploded) from Medline OR vitamin e OR alpha tocopherol* OR D1 alpha tocopherol* OR d alpha tocopherol OR rrr alpha tocopherol* OR all rac alpha tocopherol*

AND

neoplasms(exploded) from Medline OR malignant neoplastic disease(exploded) from Embase OR (cancer OR neoplasm*) in subject heading field from BIOSIS OR cancer* in title or subject heading field from all other databases OR neoplasm* from all other databases (exception - in CancerLit the terms for cancer were omitted and just the total of the “vitamin e” terms were used)

AND

(prevention OR preventive OR therapy OR therapeutic OR treatment) in title,subject heading fields

AND

human

TOTAL NUMBER OF ITEMS RETRIEVED: 1990

SEARCH #3b (PERFORMED 12/19/01)

DATABASES SEARCHED/TIME PERIOD COVERED:

Cochrane Library 1922-2001

SEARCH STRATEGY:

vitamin-e

AND

neoplasms (exploded) OR cancer*

TOTAL NUMBER OF ITEMS RETRIEVED:

Database of Abstracts of Reviews of Effectiveness

Abstracts of quality assessed systematic reviews: 1

The Cochrane Controlled Trials Register (CENTRAL/CCTR) References: 112

Co Q10 Synonyms + Cancer Search Methodology

SEARCH #4 (PERFORMED 1/18/02)

DATABASES SEARCHED/TIME PERIOD COVERED:

MEDLINE1966-2002/JAN W3
MANTIS1880-2001/Oct
Allied & Complementary Medicine1984-2001/Feb
CancerLit1975-2001/Oct
CAB HEALTH1983-2001/Dec
TGG Health&Wellness DB1976-2002/Dec W5
Biosis Previews1969-2002/Jan W2
EMBASE1974-2002/Jan W2
Social SciSearch(R)1972-2002/Jan W3
SciSearch Cited Ref Sci1990-2002/Jan W3
SciSearch Cited Ref Sci1974-1989/Dec
ELSEVIER BIOBASE1994-2002/Jan W2

SEARCH STRATEGY:

ubidecarenon? OR isoprostane? OR f2(2w)isoprostane?

AND

neoplasms(exploded) from Medline, Embase OR cancer* in title or subject heading field OR neoplasm* from all other databases (exception - in CancerLit the terms for cancer were omitted)

AND

human

TOTAL NUMBER OF ITEMS RETRIEVED: 127

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