Evidence Table 5. Epidemiology of Dysphagia in Parkinson's Disease

Study authorStudy designNumber of subjectsMean ageHow disease confirmedDisease severity, with measurement toolLength of illness
(mean)
Diagnosed symptomsDiagnostic methodIncludes LTC population?Diagnosed occurrenceMiscellaneous results
Coates and Bakheit, 1997 CS4869.9NR1.4 mean UPDRS6.7 yrsDysphagiaChicago Assessment Scale (BSE)NRNR81.1% scored <5 on at least 1 item on Chicago Assessment Scale. Mostly mild impairment.
Significant correlation btwn severity of disease and severity of dysphagia
Fuh, Lee, Wang et al., 1997 Random case series1968.4At least 2 of 3 cardinal symptoms + levodopa response1.9 mean Hoehn and Yahr3.2 yrsSwallowing problemsMBS with and without L-dopaNRNRWithout L-dopa:
Abnormal MBS:
63.2% (12/19)
Aspiration: 15.8% (3/19)
With L-dopa:
Abnormal MBS:
31.6% (6/19)
Aspiration:
5.3% (1/19)
Edwards, Quigley, Harned et al., 1994 Case-control20 (13, 7)66.6, 67.0NR22.2 mean UPDRS5.3 yrsDysphagiaGI survey; videoesophagramNRPD pts:
76.9% (10/13)
Controls:
14.3% (1/7)
On video:
Oral dysphagia 4
Pharyngeal dysphagia: 1
Esophageal dysphagia 8
No sign. Diffs from controls
Hartelius and Svensson, 1994 Survey, self-report258NRNot doneNRNRSwallowing problems25 questions, forced-choiceNRNRSwallowing problems often: 18%
Swallowing liquids often a problem: 15%
Choking often a problem: 21%
Wintzen, Badrising, Roos et al., 1994 PCS2262.7NR1.5-4 Hoehn and Yahr; 1.4 mean UPDRS6.7 yrsDysphagiaSwallowing Function Questionnaire; VFSSNRQuestionnaire:
72.7% (16/22)
VFSS:
81.1% (18/22)
No correlation between severity of disease and number of dysphagia symptoms
Singer, Weiner, and Sanchez-Ramos, 1992 Interview4865.9NR1-3 Hoehn and Yahr7.8 yrsDysphagiaQuestionnaireNR22.9% (11/48)Significantly higher incidence of dysphagia in PDs than in control group (6.3%), p<0.05
Bushmann, Dobmeyer, Leeker et al., 1989 CS2065.7NRNRNRDysphagiaQuestionnaire; MBS without L-dopa; MBS with L-dopaNRSubjective:
35% (7/20)
MBS w/o L-dopa:
Dysphagia:
75% (15/20)
Aspiration:
15% (3/20)
MBS w/ L-dopa: 5/15 dysphagics demonstrated mild to marked improvement

From: Evidence Tables

Cover of Diagnosis and Treatment of Swallowing Disorders (Dysphagia) in Acute-Care Stroke Patients
Diagnosis and Treatment of Swallowing Disorders (Dysphagia) in Acute-Care Stroke Patients.
Evidence Reports/Technology Assessments, No. 8.
ECRI Health Technology Assessment Group.

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