Declarations of interest

National Guideline Centre (UK)

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National Guideline Centre (UK). Cirrhosis in Over 16s: Assessment and Management. London: National Institute for Health and Care Excellence (NICE); 2016 Jul. (NICE Guideline, No. 50.)

Cirrhosis in Over 16s: Assessment and Management.

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Appendix BDeclarations of interest

The May 2007 version (as updated October 2008) of the NICE code of practice for declaring and dealing with conflicts of interest policy was applied to this guideline.

Iain Brew

Date	Item declared	Classification	Action taken
10/04/2014	At recruitment: GP with special interest in hepatitis C.	Personal non-financial specific	Declare and participate
	At recruitment: Contributor to the APPHG Report on Liver Disease 2014.	Personal non-financial specific	Declare and participate
	At recruitment: Has received honoraria, travel and accommodation expenses from Janssen for attending, speaking at and chairing meetings about treatment of hepatitis C.	Personal financial non-specific	Declare and participate
	At recruitment: Has received honoraria, travel and accommodation expenses from AbbVie for attending, speaking at and chairing meetings about treatment of hepatitis C.	Personal financial non-specific	Declare and participate
	At recruitment: I have received payments (£200 × 2) for articles on liver health published in the British Journal of Primary Care Nursing.	Personal financial non-specific	Declare and participate
11/07/2014	GDG1: Apologies received.	Nil	Nil
04/09/2014	GDG2: Payment for attending and chairing advisory boards for Janssen and AbbVie.	Personal financial non-specific	Declare and participate
17/10/2014	GDG3: Janssen paid for attendance at BASL in Newcastle (October 2014)	Personal financial non-specific	Declare and participate
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: Delivered a lecture on hepatitis C treatment in prisons for Gilead: honorarium payable.	Personal financial non-specific	Declare and participate
18/02/2015	GDG6: Conference and travel costs covered by Janssen for a hepatitis C meeting.	Personal financial non-specific	Declare and participate
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: AbbVie paying honorarium and travel costs 10 July meeting about hepatitis C treatments.	Personal financial non-specific	Declare and participate
29/07/2015	GDG10: Apologies received.	Nil	Nil
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: No new DOI.	Nil	Nil

David Fitzmaurice (co-optee)

Date	Item declared	Classification	Action taken
15/01/2015	None.	Nil	Nil
21/01/2015	GDG6: No new DOI.	Nil	Nil

Andrew Fowell

Date	Item declared	Classification	Action taken
21/04/2014	Recruitment: none declared.	Nil	Declare and participate
11/07/2014	GDG1: No new DOI.	Nil	Declare and participate
04/09/2014	GDG2: Received travel expenses from Janssen to attend a conference.	Personal financial non-specific	Declare and participate
04/09/2014	Secretary of the Wessex Gut Club (Gastroenterological society). Has responsibility for organising twice yearly meetings. All money paid is directly to the Gut Club. Meetings took place on the following dates and pharma company funding is outlined: November 2013: Roche, Janssen, AbbVie, Gilead, Ferring, Falk, Novartis, Vifor, Pentax July 2014: Janssen, Gilead, Falk, Tillots, Vifor, Ferring November 2014: dealt with organising programme of speakers only.	Non-personal financial non-specific	Declare and participate
04/09/2014		Roche: Non-personal financial specific	Declare and participate
17/10/2014	GDG3: No new DOI.	Nil	Nil
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: Received travel and accommodation from Janssen to attend a conference in 2015.	Personal financial non-specific	Declare and participate
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: Organised speakers for the Wessex Gut Club meeting in July 2015.	Personal non-financial non-specific	Declare and participate
02/09/2015	GDG11: Organising speakers for the Wessex Gut Club meeting taking place in November 2015.	Personal non-financial non-specific	Declare and participate
14/03/2016	GDG12: Accepted sponsorship from Gilead to attend the EASL International Liver Conference, April 2016: economy class travel, hotel accommodation and meeting registration fee.	Personal financial non-specific	Nil

Lynda Greenslade

Date	Item declared	Classification	Action taken
11/07/2014	GDG1: Norgine Advisory Board Member: 2/3 December 2013: accommodation and subsistence 8 April 2014: accommodation and subsistence Advisory Board calls: 22 and 29 June 2014	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
	GDG1: Norgine Educational Meeting Committee Member: telephone call 14 and 26 November 2013, 16 December 2013, 7 and 12 May 2014. One-off payment for being part of the education committee and a talk.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
	GDG1: Norgine-sponsored liver nurses meeting 6 and 7 June 2014: accommodation and subsistence. Payment received for chairing one session and giving one talk.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
	GDG1: Payment received from speaking at the (Norgine-sponsored) Royal College of Nursing congress on 18 June 2014.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
	GDG1: Data on hepatic encephalopathy patients from Royal Free Foundation Trust given to advisory board meeting for real world data, for Norgine.	Personal non-financial specific	Withdraw from question relating to acute hepatic encephalopathy
	GDG1: Sponsored by Norgine to go to the European Association for the Study of the Liver conference.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
04/09/2014	GDG2: Janssen paid for standard travel expenses to attend BASL Liver meeting.	Personal financial non-specific	Declare and participate
17/10/2014	GDG3: No new DOI.	Nil	Nil
26/11/2014	GDG4: Attended Norgine-sponsored Liver Nurses Educational Meeting on 21 and 22 November 2014. On the education board, chaired some sessions and gave a talk; accommodation and subsistence provided.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: Funding for travel and accommodation received from Janssen to attend the European Association for the Study of the Liver conference 2015.	Personal financial non-specific	Declare and participate
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: Attended Norgine-sponsored liver nurses meeting 15 and 16 May 2015: accommodation and subsistence. Payment for chairing one session and giving one talk.	Personal financial non-specific	Declare and participate
29/07/2015	GDG10: No new DOI.	Nil	Nil
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: No new DOI.	Nil	Nil

Phillip Harrison (Chair)

Date	Item declared	Classification	Action taken
07/01/2014	None declared	Nil	Nil
11/07/2014	GDG1: No new DOI.	Nil	Nil
04/09/2014	GDG2: No new DOI.	Nil	Nil
17/10/2014	GDG3: No new DOI.	Nil	Nil
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: No new DOI.	Nil	Nil
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: No new DOI.	Nil	Nil

Brian Hogan

Date	Item declared	Classification	Action taken
11/07/2014	GDG1: A co-investigator on a National Multicentre UK Trial of Stents in the treatment of variceal haemorrhage (UKCRN 13392). This trial receives funding from the Stent Manufacturer (Ella-CS, Czech Republic) and from the NIHR (as an on-portfolio study the NHS support costs are met by NIHR).	Non-personal financial non-specific	Declare and participate
11/07/2014	Participated in research on biomarkers of portal hypertension.	Non-personal non-financial specific	Declare and participate

04/09/2014	GDG2: No new DOI.	Nil	Nil

17/10/2014	GDG3: No new DOI.	Nil	Nil

26/11/2014	GDG4: No new DOI.	Nil	Nil

21/01/2015	GDG5: No new DOI.	Nil	Nil

18/02/2015	GDG6: No new DOI.	Nil	Nil

26/03/2015	GDG7: No new DOI.	Nil	Nil

30/04/2015	GDG8: Apologies received.	Nil	Nil

25/06/2015	GDG9: No new DOI.	Nil	Nil

29/07/2015	GDG10: No new DOI.	Nil	Nil

02/09/2015	GDG11: No new DOI.	Nil	Nil

14/03/2016	GDG12: No new DOI.	Nil	Nil

15/04/2016	Post-GDG12: Received an educational grant from Gilead to attend a ‘HCV and Transplantation’ preceptorship (accommodation and travel expenses) in June 2015.	Personal non-financial non-specific	Nil

Mark Hudson

Date	Item declared	Classification	Action taken
07/07/2014	At recruitment: Has advised Astellas on immunosuppression within the last year.	Personal financial non-specific	Declare and participate
	At recruitment: Has advised Novartis on immunosuppression within the last year.	Personal financial non-specific	Declare and participate
	At recruitment: Has advised Norgine on rifaximin within the last year.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
07/07/2014	At recruitment: I am the Co-Chief Investigator on the impact of rifaximin-α on the NHS Hospital Resource use associated with the management of patients with Hepatic Encephalopathy: A retrospective observational study (IMPRESS). The IMPRESS study is a multicentre CLRN Portfolio study funded by Norgine. The trial has been in development since April 2014. Has received no payment or personal financial gain from the IMPRESS study.	Personal non-financial specific	Withdraw from question relating to acute hepatic encephalopathy
11/07/2014	GDG1: No new DOI.	Nil	Nil
04/09/2014	GDG2: No new DOI.	Nil	Nil
17/10/2014	GDG3: Attended a Norgine advisory board on rifaximin. Received a payment on 27 October 2014 for attending a Norgine advisory board to discuss the natural history of hepatic encephalopathy.	Personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: Speaker for Norgine at a meeting (2 June) on hepatic encephalopathy. Chaired a session for Abbvie on 23 June relating to viral hepatitis.	Personal financial specific Personal financial specific	Declare and participate Declare and participate
29/07/2015	GDG10: Novartis provided travel support to attend the International Liver Transplant Society meeting in Chicago from 7 to 11 July 2015.	Personal financial non-specific	Declare and participate
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: Apologies received.	Nil	Nil

Phillip Johnson (co-optee)

Date	Item declared	Classification	Action taken
16/01/2015	At recruitment: One-off advisory board meetings: Astellas (13 February 2014) Boehringer-Ingelheim (17 October 2014).	Personal financial non-specific	Declare and participate (as a co-optee)
16/01/2015	At recruitment: funding received from Bayer Healthcare for 1-year support of research nurse/data manager from September 2014 to August 2015.	Non-personal financial non-specific	Declare and participate (as a co-optee)
26/03/2015	GDG7: Travel expenses from Wako Life Sciences to attend an American Association for the Study of Liver Diseases meeting.	Personal financial specific	Declare and participate (as a co-optee)

Andrew Langford

Date	Item declared	Classification	Action taken
27/05/2014	At recruitment: In the last year, the British Liver Trust have received: funding from Roche for the development of case studies on “Confronting the silent epidemic: a critical review of hepatitis C management in the UK” a Hepatitis Awareness Leading Outcomes report (29 April 2013) funding from Astellas as support from 2013–2014 (15 May 2013) funding from Janssen for RCGP accreditation (2 August 2014) funding from Lundbeck for PR support funding from AbbVie as honoraria (panel) funding from Galderma as honoraria (NMSC) funding from Janssen as honoraria (EASL)	Non-personal financial non-specific	Declare and participate
11/07/2014	GDG1: Apologies received.	Nil	Nil
04/09/2014	GDG2: British Liver Trust press release regarding rifaximin for hepatic encephalopathy.	Non-personal non-financial specific	Declare and participate
17/10/2014	GDG3: No new DOI.	Nil	Nil
26/11/2014	GDG4: Apologies received.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: Apologies received.	Nil	Nil
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: The British Liver Trust was gifted a Fibroscan machine by Norgine.	Non-personal financial specific	Withdraw from question relating to acute hepatic encephalopathy
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: No new DOI.	Nil	Nil
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: No new DOI.	Nil	Nil

Susan McRae

Date	Item declared	Classification	Action taken
01/07/2014	At recruitment: Employed by the Hepatitis C Trust, the UK HCV patient charity.	Personal non-financial specific	Declare and participate
11/07/2014	GDG1: No new DOI.	Nil	Nil
04/09/2014	GDG2: No new DOI.	Nil	Nil
17/10/2014	GDG3: No new DOI.	Nil	Nil
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: Expenses paid for judging quality in care hepatitis C 2015 entries, organised by PMGroup with funding from Bristol-Myers Squibb and Gilead.	Personal financial non-specific	Declare and participate
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: Apologies received.	Nil	Nil

Marsha Morgan

Date	Item declared	Classification	Action taken
27/06/2014	At recruitment: Has taken part in symposia both in the UK and abroad on aspects of alcohol dependence, alcohol-related liver disease, nutrition in chronic liver disease and hepatic encephalopathy.	Personal financial non-specific	Declare and participate
27/06/2014	At recruitment: A member of the Advisory board of the Institute of Alcohol Studies. Receive an annual stipend used to support research activities.	Personal financial non-specific	Declare and participate
11/07/2014	GDG1: No new DOI.	Nil	Nil
04/09/2014	GDG2: No new DOI.	Nil	Nil
17/10/2014	GDG3: Author of Cochrane review currently in development on hepatic encephalopathy.	Personal non-financial specific	Declare and participate
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: Apologies received.	Nil	Nil
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: No new DOI.	Nil	Nil

Gerri Mortimore

Date	Item declared	Classification	Action taken
11/07/2014	GDG1: None declared.	Nil	Nil
04/09/2014	GDG2: Apologies received.	Nil	Nil
17/10/2014	GDG3: No new DOI.	Nil	Nil
26/11/2014	GDG4: Apologies received.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: No new DOI.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: No new DOI.	Nil	Nil
02/09/2015	GDG11: Apologies received.	Nil	Nil
14/03/2016	GDG12: Apologies received.	Nil	Nil

John O'Grady (co-optee)

Date	Item declared	Classification	Action taken
22/01/2015	At recruitment: None declared.	Nil	Nil
30/04/2015	GDG8: No new DOI.	Nil	Nil

Rachel Pryke (co-optee)

Date	Item declared	Classification	Action taken
19/01/2015	At recruitment: Speaker fee for attending RCGP Conference 2 October 2014 in order to man a stand on bariatric surgery in conjunction with RCGP Nutrition Group and BOMSS, funded by Ethicon. The stand focuses on bariatric surgery care and post-surgical follow up.	Personal financial non-specific	Declare and participate (as a co-optee)
21/01/2015	GDG5: No new DOI.	Nil	Nil

Valerie Ross

Date	Item declared	Classification	Action taken
03/07/2014	At recruitment: Has contributed to advisory boards for Janssen relating to the marketing of drugs for hepatitis C within the last 12 months.	Personal financial non-specific	Declare and participate
	At recruitment: Has contributed to advisory boards for Gilead relating to the marketing of drugs for hepatitis C within the last 12 months. Payment received including travel expenses.	Personal financial non-specific	Declare and participate
	At recruitment: Gave a presentation at a Bristol-Myers Squibb training day on 14 July 2014. Presented on background to the role and responsibilities of the pharmacist in the treatment of HCV and the managed entry of new therapies in this area.	Personal financial non-specific	Declare and participate
	At recruitment: Attended British Association for the Study of the Liver meeting in Newcastle on 15 to 17 September 2014. Janssen funded reduced conference attendance fee, travel, accommodation and subsistence.	Personal financial non-specific	Declare and participate
11/07/2014	GDG1: No new DOI.	Nil	Nil
04/09/2014	GDG2: No new DOI.	Nil	Nil
17/10/2014	GDG3: Apologies received.	Nil	Nil
26/11/2014	GDG4: No new DOI.	Nil	Nil
21/01/2015	GDG5: No new DOI.	Nil	Nil
18/02/2015	GDG6: No new DOI.	Nil	Nil
26/03/2015	GDG7: Funding for travel and accommodation received from Abbvie to attend European Association for the Study of the Liver conference in April 2015.	Personal financial non-specific	Declare and participate
26/03/2015	GDG7: Attended an advisory board for AbbVie.	Personal financial non-specific	Declare and participate
30/04/2015	GDG8: No new DOI.	Nil	Nil
25/06/2015	GDG9: No new DOI.	Nil	Nil
29/07/2015	GDG10: Was a QiC Hepatitis Projects Judging panel member, sponsored by Gilead and Bristol-Myers Squibb on 14 July 2015.	Personal financial non-specific	Declare and participate
29/07/2015	GDG10: Was a presenter/facilitator at a Bristol-Myers Squibb sponsored nurse training day on 31 July 2015.	Personal financial non-specific	Declare and participate
02/09/2015	GDG11: No new DOI.	Nil	Nil
14/03/2016	GDG12: Apologies received.	Nil	Nil

Roy Sherwood (co-optee)

Date	Item declared	Classification	Action taken
11/07/2014	At recruitment: None declared.	Nil	Nil
21/01/2015	GDG5: Receives a salary from the Pathology Department at King's College London which, as of 1 January 2015, is a private company (Viapath).	Personal financial specific	Declare and participate (as a co-optee)

NGC team

Date	Declaration of interest	Classification	Action taken
11/07/2014	GDG1: In receipt of commissions.	N/A	N/A
04/09/2014	GDG2: No change to existing declarations.	N/A	N/A
17/10/2014	GDG3: No change to existing declarations.	N/A	N/A
26/11/2014	GDG4: No change to existing declarations.	N/A	N/A
21/01/2015	GDG5: No change to existing declarations.	N/A	N/A
18/02/2015	GDG6: No change to existing declarations.	N/A	N/A
	GDG6: No change to existing declarations.	N/A	N/A
26/03/2015	GDG7: No change to existing declarations.	N/A	N/A
30/04/2015	GDG8: No change to existing declarations.	N/A	N/A
25/06/2015	GDG9: No change to existing declarations.	N/A	N/A
29/07/2015	GDG10: No change to existing declarations.	N/A	N/A
02/09/2015	GDG11: No change to existing declarations.	N/A	N/A
14/03/2016	GDG12: No change to existing declarations.	N/A	N/A

NIHR team

Date	Declaration of interest	Classification	Action taken
11/07/2014	GDG1: No change to existing declarations.	N/A	N/A
04/09/2014	GDG2: No change to existing declarations.	N/A	N/A
17/10/2014	GDG3: No change to existing declarations.	N/A	N/A
26/11/2014	GDG4: No change to existing declarations.	N/A	N/A
21/01/2015	GDG5: No change to existing declarations.	N/A	N/A
18/02/2015	GDG6: No change to existing declarations.	N/A	N/A
	GDG6: No change to existing declarations.	N/A	N/A
26/03/2015	GDG7: No change to existing declarations.	N/A	N/A
30/04/2015	GDG8: No change to existing declarations.	N/A	N/A
25/06/2015	GDG9: No change to existing declarations.	N/A	N/A
29/07/2015	GDG10: No change to existing declarations.	N/A	N/A
02/09/2015	GDG11: No change to existing declarations.	N/A	N/A
14/03/2016	GDG12: No change to existing declarations.	N/A	N/A

Bookshelf ID: NBK385210

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